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Comparison of Essential and Toxic Metals Levels in some Herbal Teas: a Systematic Review

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Abstract

In the present study, we reviewed the literature as a systematic review to investigate the concentration of some metals (essential, none essential, and toxic metals) in herbal teas and their health risks. The search extended the literature from the database, including Google Scholar, PubMed, and Scopus, using the terms “herbal teas” combined with “heavy metals, essential metals, thyme, rosemary, chamomile, and tea” also with “iron, zinc, aluminum, chromium, cobalt, nickel, manganese, arsenic, cadmium, and lead” in titles and abstracts. The search was limited to articles published from 2012 to 2023 years. Initially, 212 articles were found; by detailed consideration, only 49 papers fit the inclusion criteria and were selected for further study. The mean of metal concentration, standard deviation, data distribution, and sample size were applied to generate data from the articles. The results indicated that all commonly consumed herbal teas included metals. None of them meet the requirements of the WHO requirements. However, more than 70% of their health risks are acceptable. The risks of arsenic and lead in tea and cadmium in black tea were considerably higher than in others. According to the review results, it is important to prevent heavy metal contamination of herbal teas by modifying cultivation patterns and also to prevent to consumption of low-quality herbal teas.

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References

  1. Sofowora A, Ogunbodede E, Onayade A (2013) The role and place of medicinal plants in the strategies for disease prevention. Afr J Tradit Complement Alternat Med : AJTCAM 10(5):210–229

    Google Scholar 

  2. Doğanli B (2019) Ensuring branding in rural tourism via medical aromatic herbs and an empirical study. Econ Bus Issues Retrospect Prospect 10: 355–70

  3. Ranđelović SS, Kostić DA, Zarubica AR, Mitić SS, Mitić MN (2013) The correlation of metal content in medicinal plants and their water extracts. Hemijska Industrija 67(4):585–591

    Google Scholar 

  4. Boltman-Binkowski H (2016) A systematic review: are herbal and homeopathic remedies used during pregnancy safe? Curationis 39(1):1–8

    Google Scholar 

  5. Mousavi S, Balali-Mood M, Riahi-Zanjani B, Yousefzadeh H, Sadeghi M (2013) Concentrations of mercury, lead, chromium, cadmium, arsenic and aluminum in irrigation water wells and wastewaters used for agriculture in Mashhad, northeastern Iran. Int J Occup Environ Med 4(2):60–68

    Google Scholar 

  6. Sardari S, Mobaiend A, Ghassemifard L, Kamali K, Khavasi N (2021) Therapeutic effect of thyme (Thymus vulgaris) essential oil on patients with COVID19: a randomized clinical trial. J Adv Med Biomed Res 29(133):83–91

    Google Scholar 

  7. BozdoganSert E, Turkmen M, Cetin M (2019) Heavy metal accumulation in rosemary leaves and stems exposed to traffic-related pollution near Adana-İskenderun Highway (Hatay, Turkey). Environ Monit Assess 191(9):1–12

    Google Scholar 

  8. Koshkaki MR (2020) Herbal medicines and their effects on the psyche from the Islamic teachings perspective. Arch Pharm Pract 1:40

    Google Scholar 

  9. Nieto G (2020) A review on applications and uses of thymus in the food industry. Plants 9(8):961

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Cheung S, Tai J (2007) Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis. Oncol Rep 17(6):1525–1531

    PubMed  Google Scholar 

  11. Naveed M, BiBi J, Kamboh AA, Suheryani I, Kakar I, Fazlani SA et al (2018) Pharmacological values and therapeutic properties of black tea (Camellia sinensis): a comprehensive overview. Biomed Pharmacother 100:521–531

    CAS  PubMed  Google Scholar 

  12. Gupta RC, Lall R, Srivastava A (2021) Nutraceuticals: efficacy, safety and toxicity. Academic Press

  13. Jurowski K, Krośniak M, Fołta M, Tatar B, Cole M, Piekoszewski W (2019) Safety assessment of the trace element impurities Ni and Cr in pharmaceutical herbal products for teething from polish pharmacies. Biol Trace Elem Res 191(2):517–521

    CAS  PubMed  Google Scholar 

  14. Khattak MI, Khattak MI (2011) Study of heavy trace metals in some medicinal–herbal plants of Pakistan. Pak J Bot 43(4):2003–2009

    CAS  Google Scholar 

  15. Tercan HS, Ayanoglu F, Bahadirli NP (2016) Determination of heavy metal contents and some basic aspects of widely used herbal teas in Turkey. Rev Chim 67(5):1019–1022

  16. Salahinejad M, Aflaki F (2010) Toxic and essential mineral elements content of black tea leaves and their tea infusions consumed in Iran. Biol Trace Elem Res 134(1):109–117

    CAS  PubMed  Google Scholar 

  17. Gunturu KS, Nagarajan P, McPhedran P, Goodman TR, Hodsdon ME, Strout MP (2011) Ayurvedic herbal medicine and lead poisoning. J Hematol Oncol 4(1):1–6

    Google Scholar 

  18. Chambial S, Bhardwaj P, Mahdi AA, Sharma P (2017) Lead poisoning due to herbal medications. Indian J Clin Biochem 32(2):246–247

    CAS  PubMed  Google Scholar 

  19. Karimi G, Hasanzadeh M, Nili A, Khashayarmanesh Z, Samiei Z, Nazari F et al (2008) Concentrations and health risk of heavy metals in tea samples marketed in Iran. Pharmacology 3:164–174

    Google Scholar 

  20. Zaynab M, Al-Yahyai R, Ameen A, Sharif Y, Ali L, Fatima M et al (2022) Health and environmental effects of heavy metals. J King Saud Univ-Sci 34(1):101653

    Google Scholar 

  21. Jaishankar M, Tseten T, Anbalagan N, Mathew BB, Beeregowda KN (2014) Toxicity, mechanism and health effects of some heavy metals. Interdiscip Toxicol 7(2):60

    PubMed  PubMed Central  Google Scholar 

  22. Yim JH, Kim KW, Kim SD (2006) Effect of hardness on acute toxicity of metal mixtures using Daphnia magna: prediction of acid mine drainage toxicity. J Hazard Mater 138(1):16–21

    CAS  PubMed  Google Scholar 

  23. Muhammad S, Shah MT, Khan S (2011) Health risk assessment of heavy metals and their source apportionment in drinking water of Kohistan region, northern Pakistan. Microchem J 98(2):334–343

    CAS  Google Scholar 

  24. Obón C, Rivera D, Fonollá E, Alcaraz F, Attieh L (2021) A comparison study on traditional mixtures of herbal teas used in eastern Mediterranean area. Front Pharmacol 12:6923

    Google Scholar 

  25. García-Galdeano JM, Villalón-Mir M, Medina-Martínez J, Vázquez-Foronda LM, Zamora-Bustillos JG, Agil A et al (2020) Zn, Cu, and Fe concentrations in dehydrated herbs (thyme, rosemary, cloves, oregano, and basil) and the correlation with the microbial counts of listeria monocytogenes and other foodborne pathogens. Foods 9(11):1658

    PubMed  PubMed Central  Google Scholar 

  26. Potortì AG, Bua GD, Turco VL, Tekaya AB, Beltifa A, Mansour HB et al (2020) Major, minor and trace element concentrations in spices and aromatic herbs from Sicily (Italy) and Mahdia (Tunisia) by ICP-MS and multivariate analysis. Food Chem 313:126094

    PubMed  Google Scholar 

  27. Bua DG, Annuario G, Albergamo A, Cicero N, Dugo G (2016) Heavy metals in aromatic spices by inductively coupled plasma-mass spectrometry. Food Addit Contam: Part B 9(3):210–216

    CAS  Google Scholar 

  28. Krstić M, Stupar M, Đukić-Ćosić D, Baralić K, Mračević SĐ (2021) Health risk assessment of toxic metals and toxigenic fungi in commercial herbal tea samples from Belgrade, Serbia. J Food Compos Anal 104:104159

    Google Scholar 

  29. Zazouli MA, Bandpei AM, Maleki A, Saberian M, Izanloo H (2010) Determination of cadmium and lead contents in black tea and tea liquor from Iran. Asian J Chem 22(2):1387

    CAS  Google Scholar 

  30. Maghrabi IA (2014) Determination of some mineral and heavy metals in Saudi Arabia popular herbal drugs using modern techniques. Afr J Pharm Pharmacol 8(36):893–898

    Google Scholar 

  31. Shim J, Cho T, Leem D, Cho Y, Lee C (2019) Heavy metals in spices commonly consumed in Republic of Korea. Food Addit Contam: Part B 12(1):52–58

    CAS  Google Scholar 

  32. Softić N, Makić H, Trumić E, Keran H, Ahmetović M (2021) Risk assessment of heavy metal Fe, Mn, Zn and Cu intake by consuming herbal tea thyme. Int J Res Appl Sci Biotechnol 8(2):259–261

    Google Scholar 

  33. Karimi M, Tayebi L, Sobhanardakani S (2016) Pb and Cd in medicinal plants (case study: Shirazi thyme, sweet violet, pennyroyal and jujube). J Kermanshah Univ Med Sci 20(3):6–111

    Google Scholar 

  34. Nodushan SKH, Emtiazy M, Salmani MH, Lotfi MH, Zadeh ME (2020) Monitoring of essential and toxic elements in leaves, branches, and stem of Prosopis cineraria (as anti-inflammatory) growing in Iran. Biol Trace Elem Res 198(2):714–720

    CAS  PubMed  Google Scholar 

  35. Pourramezani F, AkramiMohajeri F, Salmani MH, DehghaniTafti A, Khalili SE (2019) Evaluation of heavy metal concentration in imported black tea in Iran and consumer risk assessments. Food Sci Nutr 7(12):4021–4026

    CAS  PubMed  PubMed Central  Google Scholar 

  36. Hashemi PRM, Rahimi A, Ghiasvand AR, Hosseini F (2017) A study of the pollution of ten popular medicinal plants by heavy metals in Khoramabad (Iran). Zanko J Med Sci 15:17–25

    Google Scholar 

  37. Abdi S, Shams K, Kobraee S (2017) Measurement of heavy metals, lead and cadmium, in ten major medicinal plants in Kermanshah. Appl Biol 6(24):43–50

    Google Scholar 

  38. Karimi MTL, Sobhanardakani S (2017) Levels and health risk assessment of As and Zn in Shirazi thyme, sweet violet, pennyroyal and jujube marketed in Hamedan City. J Food Hyg 6(24):43–52

    Google Scholar 

  39. Jurowski K, Krośniak M (2023) Cadmium impurities in traditional herbal medicinal products with Thymi herba available in Polish pharmacies–short communication: the level of Cd impurities and comprehensive toxicological risk assessment. Nat Prod Res 37(5):840–846

    CAS  PubMed  Google Scholar 

  40. Kanrar B, Kundu S, Khan P (2022) Elemental profiling of north-east Indian tea (Camellia sinensis) by ICP-MS and assessment of associated health risk. Biol Trace Elem Res. https://doi.org/10.1007/s12011-022-03457-3

  41. Kowalska G (2021) The safety assessment of toxic metals in commonly used herbs, spices, tea, and coffee in Poland. Int J Environ Res Public health 18(11):5779

    CAS  PubMed  PubMed Central  Google Scholar 

  42. Zuo T-T, Jin H-Y, Zhang L, Liu Y-L, Nie J, Chen B-I et al (2020) Innovative health risk assessment of heavy metals in Chinese herbal medicines based on extensive data. Pharmacol Res 159:104

    Google Scholar 

  43. Cy P, Zhu Xh, Ry H, Gf Ge, Rm H, Xc W et al (2018) Aluminum and heavy metal accumulation in tea leaves: an interplay of environmental and plant factors and an assessment of exposure risks to consumers. J Food Sci 83(4):1165–1172

    Google Scholar 

  44. Ozyigit II, Yalcin B, Turan S, Saracoglu IA, Karadeniz S, Yalcin IE et al (2018) Investigation of heavy metal level and mineral nutrient status in widely used medicinal plants’ leaves in Turkey: insights into health implications. Biol Trace Elem Res 182(2):387–406

    CAS  PubMed  Google Scholar 

  45. Schunk PFT, Kalil IC, Pimentel-Schmitt EF, Lenz D, de Andrade TU, Ribeiro JS et al (2016) ICP-OES and micronucleus test to evaluate heavy metal contamination in commercially available Brazilian herbal teas. Biol Trace Elem Res 172(1):258–265

    CAS  PubMed  Google Scholar 

  46. Dghaim R, Al Khatib S, Rasool H, Ali KM (2015) Determination of heavy metals concentration in traditional herbs commonly consumed in the United Arab Emirates. J Environ Public Health 2015:973878

    PubMed  PubMed Central  Google Scholar 

  47. Baye H, Hymete A (2013) Levels of heavy metals in common medicinal plants collected from environmentally different sites. Middle-East J Sci Res 13(7):938–943

    CAS  Google Scholar 

  48. Mandiwana KL, Panichev N, Panicheva S (2011) Determination of chromium (VI) in black, green and herbal teas. Food Chem 129(4):1839–1843

    CAS  Google Scholar 

  49. Naithani V, Kakkar P (2005) Evaluation of heavy metals in Indian herbal teas. Bull Environ Contam Toxicol 75(1):197–203

    CAS  PubMed  Google Scholar 

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MHS contributed to the conception and design of the study. MJR and FM performed searching articles. MHS and MG wrote the main manuscript text. All authors read and approved the final manuscript.

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Correspondence to Mohammad Hossein Salmani.

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Salmani, M.H., Gholami, M., Ranjbar, M.J. et al. Comparison of Essential and Toxic Metals Levels in some Herbal Teas: a Systematic Review. Biol Trace Elem Res 202, 615–623 (2024). https://doi.org/10.1007/s12011-023-03698-w

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