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Sensitive and Reliable Ascorbic Acid Sensing by Lanthanum Oxide/Reduced Graphene Oxide Nanocomposite

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Abstract

A simple strategy for the detection and estimation of ascorbic acid (AA), using lanthanum oxide–reduced graphene oxide nanocomposite (LO/RGO) on indium tin oxide (ITO) substrate, is reported. LO/RGO displays high catalytic activity toward the oxidation of AA, and the synergism between lanthanum oxide and reduced graphene oxide was attributed to the successful and efficient detection. Detection mechanism and sensing efficacy of LO/RGO nanocomposite are investigated by electrochemical techniques. Chronoamperometric results under optimal conditions show a linear response range from 14 to 100 μM for AA detection. Commercially available vitamin C tablets were also analyzed using the proposed LO/RGO sensor, and the remarkable recovery percentage (97.64–99.7) shows the potential application in AA detection.

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Acknowledgments

We greatly acknowledge Department of Science and Technology (SERB), India for funding through the project no-SR/FT/CS-123/2010 dated 08/02/2012. We are also Thankful to the CSIR (Council of Scientific & Industrial Research) FOR Senior research fellowship to VS.

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Authors and Affiliations

  1. Department of Chemistry, University of Delhi, Delhi, 110007, India

    Navin Kumar Mogha, Vikrant Sahu, Raj Kishore Sharma & Dhanraj T. Masram

  2. Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, 110007, India

    Meenakshi Sharma

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  1. Navin Kumar Mogha
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  2. Vikrant Sahu
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  3. Meenakshi Sharma
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  4. Raj Kishore Sharma
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Correspondence to Raj Kishore Sharma or Dhanraj T. Masram.

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Mogha, N.K., Sahu, V., Sharma, M. et al. Sensitive and Reliable Ascorbic Acid Sensing by Lanthanum Oxide/Reduced Graphene Oxide Nanocomposite. Appl Biochem Biotechnol 174, 1010–1020 (2014). https://doi.org/10.1007/s12010-014-0986-z

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  • DOI: https://doi.org/10.1007/s12010-014-0986-z

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