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Infrapatellar Saphenous Neuralgia After TKA Can Be Improved With Ultrasound-guided Local Treatments

  • Symposium: 2014 Knee Society Proceedings
  • Published:
Clinical Orthopaedics and Related Research®

Abstract

Background

Current opinion suggests that in some patients, chronic pain after total knee arthroplasty (TKA) has a neuropathic origin. Injury to the infrapatellar branch of the saphenous nerve (IPSN) has been implicated as a cause of medial knee pain; however, local treatments for this condition remain controversial.

Questions/purposes

We sought to explore the efficacy of local treatment to the IPSN in patients with persistent medial knee pain after TKA.

Methods

In this retrospective series, 16 consecutive patients with persistent medial knee pain after primary or revision TKA were identified after other potential etiologies of knee pain were excluded. Using advanced ultrasound imaging to identify the IPSN, hydrodissection of the nerve from the adjacent interfascial planes was performed followed by corticosteroid injection (local treatment). In two patients, radiofrequency ablation of the IPSN was subsequently performed for recurrent symptoms. The outcome measure of this study was patient-reported relief of medial knee pain based on a visual analog scale (VAS) score of 0 to 10 either at rest or with activity, whichever resulted in more pain for the patient. Followup was at a minimum of 6 months (median, 9 months; range, 6–12 months). Before the procedure, the median highest VAS pain score, either at rest or with activity, was 8 of 10 (range, 6–10).

Results

Local injections to the infrapatellar saphenous nerve (one or two injections) improved medial pain after TKA to a VAS score of 0 or 1 in nine of our 16 patients. Three patients reported pain improvement to VAS levels of 3 to 4. Of the remaining four patients, two did not have improvement with VAS scores of 8, and two underwent subsequent radiofrequency ablation of the IPSN with resolution of pain in one patient.

Conclusions

In summary, we believe injury to the IPSN may be an underappreciated cause of persistent medial pain after TKA. We report favorable preliminary results with local treatment to the nerve in nine of our 16 patients, suggesting that the neuritis is a reversible process in some patients; however, because of the possibility of a placebo effect, we believe this treatment modality should be tested in a randomized, placebo-controlled trial.

Level of Evidence

Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

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Acknowledgments

We thank Ms. Kelly Viola ELS, for her assistance in manuscript preparation.

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Correspondence to Steven Clendenen MD.

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Each author certifies that he or she, or a member of his or her immediate family, has no funding or commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.

All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research ® editors and board members are on file with the publication and can be viewed on request.

Clinical Orthopaedics and Related Research ® neither advocates nor endorses the use of any treatment, drug, or device. Readers are encouraged to always seek additional information, including FDA-approval status, of any drug or device prior to clinical use.

Each author certifies that his or her institution approved the human protocol for this investigation, that all investigations were conducted in conformity with ethical principles of research, and that informed consent for participation in the study was obtained.

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Clendenen, S., Greengrass, R., Whalen, J. et al. Infrapatellar Saphenous Neuralgia After TKA Can Be Improved With Ultrasound-guided Local Treatments. Clin Orthop Relat Res 473, 119–125 (2015). https://doi.org/10.1007/s11999-014-3812-6

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  • DOI: https://doi.org/10.1007/s11999-014-3812-6

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