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Management of Pancreatic Cystic Lesions: Making Sense of All the Guidelines

  • Pancreas (C Forsmark, Section Editor)
  • Published:
Current Treatment Options in Gastroenterology Aims and scope Submit manuscript

Abstract

Purpose of review

Pancreatic cystic lesions are now being identified in increasing frequency, providing an opportunity for early detection of advanced neoplasia. Multiple guidelines have been developed to help risk-stratify pancreatic cystic lesions. However, differences between guidelines provide a source of confusion for most practitioners. In this review, we attempt to highlight the similarities and differences between the guidelines, specifically evaluating their target populations and variations in surveillance/management strategies for pancreatic cystic lesions.

Recent findings

The most commonly used guidelines provide varying strategies for the management and surveillance of pancreatic cystic lesions. By providing a consolidated and updated review of the literature, we find no one guideline performs better than the others.

Summary

Despite existing guidelines, the most optimal risk stratification strategy for pancreatic cystic lesions remains unclear. However, advances in enhanced imaging modalities, cyst fluid analysis, and other biomarkers may offer effective options in the future.

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Authors and Affiliations

  1. Division of Gastroenterology and Hepataology, Baylor College of Medicine, Houston, TX, USA

    Salmaan Jawaid MD

  2. Division of Gastroenterology and Hepatology, University of Florida Health, Gainesville, FL, USA

    Peter V. Draganov MD & Dennis Yang MD

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  1. Salmaan Jawaid MD
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Conception and design: Salmaan Jawaid and Dennis Yang. Final approval of manuscripts: all authors

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Correspondence to Salmaan Jawaid MD.

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Salmaan Jawaid declares that he has no conflict of interest.

Peter Draganov is a consultant for Boston Scientific Corp, Olympus.

Dennis Yang is a consultant for Boston Scientific.

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Jawaid, S., Draganov, P.V. & Yang, D. Management of Pancreatic Cystic Lesions: Making Sense of All the Guidelines. Curr Treat Options Gastro 18, 682–698 (2020). https://doi.org/10.1007/s11938-020-00321-y

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