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Lymph Node Staging in Prostate Cancer

  • New Imaging Techniques (A Rastinehad and S Rais-Bahrami, Section Editors)
  • Published:
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Abstract

Nodal staging is important in prostate cancer treatment. While surgical lymph node dissection is the classic method of determining whether lymph nodes harbor malignancy, this is a very invasive technique. Current noninvasive approaches to identifying malignant lymph nodes are limited. Conventional imaging methods rely on size and morphology of lymph nodes and have notoriously low sensitivity for detecting malignant nodes. New imaging techniques such as targeted positron emission tomography (PET) imaging and magnetic resonance lymphography (MRL) with iron oxide particles are promising for nodal staging of prostate cancer. In this review, the strengths and limitations of imaging techniques for lymph node staging of prostate cancer are discussed.

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Dr. Sandeep Sankineni, Dr. Anna M. Brown, Dr. Michele Fascelli, Dr. Yan Mee Law, Dr. Peter A. Pinto, Dr. Peter L. Choyke, and Dr. Baris Turkbey each declare no potential conflicts of interest.

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Authors and Affiliations

  1. Molecular Imaging Program, National Cancer Institute, National Institutes of Health, 10 Center Drive, Building 10, Room B3B85, Bethesda, MD, USA

    Sandeep Sankineni, Anna M. Brown, Peter L. Choyke & Baris Turkbey

  2. Duke University School of Medicine, Durham, NC, USA

    Anna M. Brown

  3. Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

    Michele Fascelli & Peter A. Pinto

  4. Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA

    Michele Fascelli

  5. Department of Diagnostic Radiology, Singapore General Hospital, Singapore, Singapore

    Yan Mee Law

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Sankineni, S., Brown, A.M., Fascelli, M. et al. Lymph Node Staging in Prostate Cancer. Curr Urol Rep 16, 30 (2015). https://doi.org/10.1007/s11934-015-0505-y

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