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Contemporary Gender-Specific Outcomes in Germany After Radical Cystectomy for Bladder Cancer

  • Urothelial Cancer (A Sagalowsky, Section Editor)
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Abstract

In 2008, urothelial carcinoma of the bladder (UCB) was the 8th most common cause of death in Germany. An increasing body of evidence suggests differences in the presentation and prognosis of UCB between genders. Large population-based and multi-institutional studies have found a higher incidence of UCB in men, while women treated with radical cystectomy (RC) have shown unfavorable outcomes compared to their male counterparts. Indeed, it is important to note that UCB incidence and outcomes have regional and country-specific variability. These distinct country and gender-specific differences must be considered in patient counseling, treatment decisions, and UCB management. This review summarizes the contemporary literature regarding the impact of gender on UCB outcomes, focusing on patients treated with RC in Germany. We evaluated the most current literature regarding gender-specific differences in UCB incidence, treatment patterns, and oncological outcomes, including pathological stage distribution and survival.

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Conflict of Interest

Dr. Marianne Schmid, Dr. Shahrokh F. Shariat, Dr. Armin Soave, Dr. Oliver Engel, and Dr. Margit Fisch each declare no potential conflicts of interest.

Dr. Michael Rink receives the GEROK research grant of the University of Hamburg.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Department of Urology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany

    Marianne Schmid, Armin Soave, Oliver Engel, Margit Fisch & Michael Rink

  2. Department of Urology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria

    Shahrokh F. Shariat

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  1. Marianne Schmid
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  2. Shahrokh F. Shariat
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Correspondence to Michael Rink.

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This article is part of the Topical Collection on Urothelial Cancer

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Schmid, M., Shariat, S.F., Soave, A. et al. Contemporary Gender-Specific Outcomes in Germany After Radical Cystectomy for Bladder Cancer. Curr Urol Rep 15, 409 (2014). https://doi.org/10.1007/s11934-014-0409-2

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