Abstract
Purpose of Review
To evaluate the medical literature regarding the effects of cannabis use on female sexual function in order to provide healthcare professionals with a summary of the most recent data.
Recent Findings
Limited data has shown that there is a correlation between cannabis use and an improvement in female sexual function in some settings at moderate doses. Cannabis use at moderate doses may positively affect several domains of sexual function, such as orgasm, libido, and arousal, dissimilarly. Cannabis use at high doses may have negative effects on female sexual function.
Summary
Small studies of poor quality have determined that the use of moderate amounts of cannabis during the sexual experience may improve female sexual function. However, further research is needed, specifically randomized, placebo-controlled trials, to determine the effects of cannabis on different domains of sexual experiences as well as the sexual experience as a whole. Current data has shown that cannabis may have both positive and negative effects depending on the dosage, frequency of use, and domain of sexual experience in question. Nonetheless, with cannabis becoming legalized and used frequently in more states, it is imperative that we understand its effects on female sexuality.
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References
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Lynn BK, López JD, Miller C, Thompson J, Campian EC. The relationship between marijuana use prior to sex and sexual function in women. Sex Med. 2019;7(2):192–7. https://doi.org/10.1016/j.esxm.2019.01.003. When this research was published, it was the largest study to date evaluating women’s perceptions of the sexual experience when using cannabis. This study found an association between marijuana use and orgasm satisfaction, as well as an improvement in other domains of sexual function. The findings of this research paved the way for further studies looking at cannabis use and sexual function.
Gaoni Y, Mechoulam R. Isolation, structure, and partial synthesis of an active constituent of Hashish. J Am Chem Soc. 1964;86(8):1646–7. https://doi.org/10.1021/ja01062a046.
Lowe H, Toyang N, Steele B, Bryant J, Ngwa W. The endocannabinoid system: a potential target for the treatment of various diseases. Int J Mol Sci. 2021;22(17):9472. https://doi.org/10.3390/ijms22179472.
Lynn B, Gee A, Zhang L, Pfaus JG. Effects of cannabinoids on female sexual function. Sex Med Rev. 2020;8(1):18–27. https://doi.org/10.1016/j.sxmr.2019.07.004.
Pertwee RG. Cannabinoid receptors and pain. Prog Neurobiol. 2001;63(5):569–611. https://doi.org/10.1016/s0301-0082(00)00031-9.
Brents LK. Marijuana, the Endocannabinoid system and the female reproductive system. Yale J Biol Med. 2016;89(2):175–91.
Ryan KL, Arbuckle-Bernstein V, Smith G, Phillips J. Let’s talk about sex: a survey of patients’ preferences when addressing sexual health concerns in a family medicine residency program office. PRiMER. 2018;11(2):23. https://doi.org/10.22454/PRiMER.2018.728252.
Shifren JL, Monz BU, Russo PA, Segreti A, Johannes CB. Sexual problems and distress in United States women: prevalence and correlates. Obstet Gynecol. 2008;112(5):970–8. https://doi.org/10.1097/AOG.0b013e3181898cdb.
McCabe MP, Sharlip ID, Lewis R, Atalla E, Balon R, Fisher AD, Laumann E, Lee SW, Segraves RT. Incidence and prevalence of sexual dysfunction in women and men: a consensus statement from the Fourth International Consultation on Sexual Medicine 2015. J Sex Med. 2016;13(2):144–52. https://doi.org/10.1016/j.jsxm.2015.12.034.
Nahas GG, Greenwood A. The first report of the National Commission on marihuana (1972): signal of misunderstanding or exercise in ambiguity. Bull N Y Acad Med 1974. 1972;50(1):55–75.
Koff WC. Marijuana and sexual activity. J Sex Res. 1974;10(3):194–204. https://doi.org/10.1080/00224497409550850.
Halikas J, Weller R, Morse C. Effects of regular marijuana use on sexual performance. J Psychoactive Drugs. 1982;14(1–2):59–70. https://doi.org/10.1080/02791072.1982.10471911.
Palamar JJ, Acosta P, Ompad DC, Friedman SR. A qualitative investigation comparing psychosocial and physical sexual experiences related to alcohol and marijuana use among adults. Arch Sex Behav. 2018;47(3):757–70. https://doi.org/10.1007/s10508-016-0782-7.
Sun AJ, Eisenberg ML. Association between marijuana use and sexual frequency in the United States: a population-based study. J Sex Med. 2017;14:1342–7. https://doi.org/10.1016/j.jsxm.2017.09.005.
Wiegel M, Meston C, Rosen R. The female sexual function index (FSFI): cross-validation and development of clinical cutoff scores. J Sex Marital Ther. 2005;31(1):1–20. https://doi.org/10.1080/00926230590475206.
Kasman AM, Bhambhvani HP, Wilson-King G, Eisenberg ML. Assessment of the association of cannabis on female sexual function with the Female Sexual Function Index. Sex Med. 2020;8(4):699–708. https://doi.org/10.1016/j.esxm.2020.06.009. This research used the validated Female Sexual Function Index (FSFI) questionnaire and is the largest FSFI questionnaire study to date. The study found a direct correlation between cannabis users and an improvement in FSFI score, meaning better overall sexual function. This study also noted that the method of consumption did not alter the FSFI score; these were the first results of this nature regarding method of consumption and sexual function.
Wiebe E, Just A. How Cannabis Alters Sexual Experience: A Survey of Men and Women. J Sex Med. 2019;16(11):1758–62. https://doi.org/10.1016/j.jsxm.2019.07.023.
Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: results from the 2020 National Survey on Drug Use and Health (HHS Publication No. PEP21–07–01–003, NSDUH Series H-56). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. 2021: Retrieved from https://www.samhsa.gov/data/. Accessed 20 July 2022.
Roman P, Ortiz-Rodriguez A, Romero-Lopez A, Rodriguez-Arrastia M, Ropero-Padilla C, Sanchez-Labraca N, Rueda-Ruzafa L. The influence of cannabis and alcohol use on sexuality: an observational study in young people (18–30 years). Healthcare (Basel). 2021;10(1):71. https://doi.org/10.3390/healthcare10010071.
Ashton CH. Pharmacology and effects of cannabis: a brief review. Br J Psychiatry. 2001;178:101–6. https://doi.org/10.1192/bjp.178.2.101.
Sumnall HR, Beynon CM, Conchie SM, Riley SC, Cole JC. An investigation of the subjective experiences of sex after alcohol or drug intoxication. J Psychopharmacol. 2007;21(5):525–37. https://doi.org/10.1177/0269881106075590.
Halikas J, Weller R, Morse C. Effects of regular marijuana use on sexual performance. J Psychoactive Drugs. 1982;14(1–2):59–70. https://doi.org/10.1080/02791072.1982.10471911.
Tinklenberg JR, Roth WT, Kopell BS. Marijuana and ethanol: differential effects on time perception, heart rate, and subjective response. Psychopharmacol (Berl). 1976;49(3):275–9. https://doi.org/10.1007/BF00426830.
Sewell RA, Schnakenberg A, Elander J, Radhakrishnan R, Williams A, Skosnik PD, Pittman B, Ranganathan M, D’Souza DC. Acute effects of THC on time perception in frequent and infrequent cannabis users. Psychopharmacology. 2013;26(2):401–13. https://doi.org/10.1007/s00213-012-2915-6.
Tart CT. Marijuana intoxication common experiences. Nature. 1970;226(5247):701–4. https://doi.org/10.1038/226701a0.
Pfaus JG. Pathways of sexual desire. J Sex Med. 2009;6(6):1506–33. https://doi.org/10.1111/j.1743-6109.2009.01309.x.
Stahl SM. Circuits of sexual desire in hypoactive sexual desire disorder. J Clin Psychiatry. 2010;71(5):518–9. https://doi.org/10.4088/JCP.10bs06115whi.
Mulvehill S, Tishler J. Four theories support a hypothesis that cannabis may be a treatment for female orgasmic disorder. J Sex Med. 2022;19:209–10. https://doi.org/10.1016/j.jsxm.2022.03.476. This study was the first of any research to specifically discuss orgasms. It also contained a novel description of the framework for each of the four theories explaining how cannabis use might improve an orgasm.
Ladha KS, Ajrawat P, Yang Y, Clarke H. Understanding the Medical Chemistry of the Cannabis Plant is Critical to Guiding Real World Clinical Evidence. Molecules. 2020;25(18):4042. https://doi.org/10.3390/molecules25184042.
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Kipping, A., Lynn, B. Effects of Cannabis Use on Sexual Function in Women: a Review. Curr Sex Health Rep 14, 200–206 (2022). https://doi.org/10.1007/s11930-022-00339-6
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DOI: https://doi.org/10.1007/s11930-022-00339-6