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Epidemiology of Psoriasis and Psoriatic Arthritis in Italy—a Systematic Review

  • Psoriatic Arthritis (J Scher, Section Editor)
  • Published:
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Abstract

Purpose of Review

Understanding prevalence of diseases within specific regions of a country is important for optimal allocation of healthcare resources/funds. We performed a systematic review to obtain a clearer picture of the epidemiology of psoriasis and psoriatic arthritis across and within specific regions of Italy.

Recent Findings

Prevalence of psoriasis in specific regions showed more variability (0.8–4.5%) than that in the total population (1.8–3.1%). Prevalence of psoriatic arthritis in the general population was reported for only two regions, Chiavari (0.09%) and Marche (0.42%). All other studies reported prevalence of psoriatic arthritis in patients with psoriasis in single centres and Italy-wide (4.7–47.1%). Prevalence of psoriatic arthritis was highest in patients with nail and/or scalp psoriasis and/or intergluteal/perianal region involvement.

Summary

Based on current available data, these conditions appear to affect a substantial number of people and will likely have an important impact on the Italian healthcare system.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. •• World Health Organization. Global report on psoriasis. 2016. Available at http://apps.who.int/iris/bitstream/10665/204417/1/9789241565189_eng.pdf. Accessed 09 Aug 2017. This report provides an extensive global overview of psoriasis and the burden and impact on quality of life of psoriasis.

  2. Cimmino MA. Epidemiology of psoriasis and psoriatic arthritis. Reumatismo. 2007;59(Suppl 1):19–24.

    PubMed  Google Scholar 

  3. Lebwohl MG, Bachelez H, Barker J, Girolomoni G, Kavanaugh A, Langley RG, et al. Patient perspectives in the management of psoriasis: results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis Survey. J Am Acad Dermatol. 2014;70(5):871–81.e1–30.

    Article  PubMed  Google Scholar 

  4. Armstrong AW, Schupp C, Wu J, Bebo B. Quality of life and work productivity impairment among psoriasis patients: findings from the National Psoriasis Foundation survey data 2003-2011. PLoS One. 2012;7:e52935.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Christophers E, Barker JN, Griffiths CE, Daudén E, Milligan G, Molta C, et al. The risk of psoriatic arthritis remains constant following initial diagnosis of psoriasis among patients seen in European dermatology clinics. J Eur Acad Dermatol Venereol. 2010;24(5):548–54.

    Article  PubMed  CAS  Google Scholar 

  6. Patrizi A, Venturi M, Scorzoni R, Pazzaglia M, Malavolta N, Bardazzi F. Nail dystrophies, scalp and intergluteal/perianal psoriatic lesions: risk factors for psoriatic arthritis in mild skin psoriasis? G Ital Dermatol Venereol. 2014;149(2):177–84.

    PubMed  CAS  Google Scholar 

  7. Bonifati C, Elia F, Francesconi F, Ceralli F, Izzi S, Solivetti FM, et al. The diagnosis of early psoriatic arthritis in an outpatient dermatological centre for psoriasis. J Eur Acad Dermatol Venereol. 2012;26(5):627–33.

    Article  PubMed  CAS  Google Scholar 

  8. Gisondi P, Girolomoni G, Sampogna F, Tabolli S, Abeni D. Prevalence of psoriatic arthritis and joint complaints in a large population of Italian patients hospitalised for psoriasis. Eur J Dermatol. 2005;15(4):279–83.

    PubMed  Google Scholar 

  9. Vena GA, Altomare G, Ayala F, Berardesca E, Calzavara-Pinton P, Chimenti S, et al. Incidence of psoriasis and association with comorbidities in Italy: a 5-year observational study from a national primary care database. Eur J Dermatol. 2010;20(5):593–8.

    PubMed  Google Scholar 

  10. Hanova P, Pavelka K, Holcatova I, Pikhart H. Incidence and prevalence of psoriatic arthritis, ankylosing spondylitis, and reactive arthritis in the first descriptive population-based study in the Czech Republic. Scand J Rheumatol. 2010;39:310–7.

    Article  PubMed  CAS  Google Scholar 

  11. Gelfand JM, Stern RS, Nijsten T, Feldman SR, Thomas J, Kist J, et al. The prevalence of psoriasis in African Americans: results from a population-based study. J Am Acad Dermatol. 2005;52:23–6.

    Article  PubMed  Google Scholar 

  12. Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535.

    Article  PubMed  PubMed Central  Google Scholar 

  13. De Angelis R, Salaffi F, Grassi W. Prevalence of spondyloarthropathies in an Italian population sample: a regional community-based study. Scand J Rheumatol. 2007;36(1):14–21.

    Article  PubMed  Google Scholar 

  14. Salaffi F, De Angelis R, Grassi W, MArche Pain Prevalence; INvestigation Group (MAPPING) study. Prevalence of musculoskeletal conditions in an Italian population sample: results of a regional community-based study. I. The MAPPING study. Clin Exp Rheumatol. 2005;23(6):819–28.

    PubMed  CAS  Google Scholar 

  15. Sardu C, Cocco E, Mereu A, Massa R, Cuccu A, Marrosu MG, et al. Population based study of 12 autoimmune diseases in Sardinia, Italy: prevalence and comorbidity. PLoS One. 2012;7(3):e32487.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  16. Saraceno R, Mannheimer R, Chimenti S. Regional distribution of psoriasis in Italy. J Eur Acad Dermatol Venereol. 2008;22(3):324–9.

    Article  PubMed  CAS  Google Scholar 

  17. Naldi L, Colombo P, Placchesi EB, Piccitto R, Chatenoud L, La Vecchia C, et al. Study design and preliminary results from the pilot phase of the PraKtis study: self-reported diagnoses of selected skin diseases in a representative sample of the Italian population. Dermatology. 2004;208(1):38–42.

    Article  PubMed  Google Scholar 

  18. Cimmino MA, Zampogna A, Murroni S, Baruffi S, Alessio G, Maio T, et al. Methodology of an epidemiologic prevalence study in rheumatology: the Chiavari study [in Italian]. Reumatismo. 2002;54(1):40–7.

    PubMed  CAS  Google Scholar 

  19. • Dini V, Martini P, Bellini M, Bagnoni G, Marsili F, Lancia U. Psoriatic arthritis prevalence in the clinical practice of dermatologists in North-West Tuscany centres of excellence for psoriasis: a screening experience. G Ital Dermatol Venereol. 2017;152:24–7. This study provides insights into the presentation of arthritis in patients with psoriasis and differences between patients with psoriasis with and without arthritis in a clinical setting.

    PubMed  Google Scholar 

  20. • Piaserico S, Gisondi P, Amerio P, Amoruso G, Campanati A, Conti A, et al. Validation and field performance of the Italian version of the Psoriatic Arthritis Screening and Evaluation (PASE) questionnaire. Acta Derm Venereol. 2016;96(217):96–101. This study validates the Italian version of the Psoriatic Arthritis Screening and Evaluation questionnaire in a real-world setting across multiple dermatology clinics in Italy.

    PubMed  Google Scholar 

  21. De Marco G, Cattaneo A, Battafarano N, Lubrano E, Carrera CG, Marchesoni A. Not simply a matter of psoriatic arthritis: epidemiology of rheumatic diseases in psoriatic patients. Arch Dermatol Res. 2012;304(9):719–26.

    Article  PubMed  Google Scholar 

  22. Altobelli E, Maccarone M, Petrocelli R, Marziliano C, Giannetti A, Peris K, et al. Analysis of health care and actual needs of patients with psoriasis: a survey on the Italian population. BMC Public Health. 2007;7:59.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Finzi AF, Benelli C. A clinical survey of psoriasis in Italy: 1st AISP report. Interdisciplinary Association for the Study of Psoriasis. J Eur Acad Dermatol Venereol. 1998;10(2):125–9.

    Article  PubMed  CAS  Google Scholar 

  24. Salvarani C, Lo Scocco G, Macchioni P, Cremonesi T, Rossi F, Mantovani W, et al. Prevalence of psoriatic arthritis in Italian psoriatic patients. J Rheumatol. 1995;22(8):1499–503.

    PubMed  CAS  Google Scholar 

  25. De Marco G, Cattaneo A, Carrera CG, Gibertini P, Battafarano N, Marchesoni A. The EPIPSOFIRE project: a preliminary report. Drug Dev Res. 2014;75(Suppl 1):S85–7.

    Article  PubMed  CAS  Google Scholar 

  26. Tinazzi I, Adami S, Zanolin EM, Caimmi C, Confente S, Girolomoni G, et al. The early psoriatic arthritis screening questionnaire: a simple and fast method for the identification of arthritis in patients with psoriasis. Rheumatology (Oxford). 2012;51(11):2058–63.

    Article  Google Scholar 

  27. Cervini C, Leardini G, Mathieu A, Punzi L, Scarpa R. Psoriatic arthritis: epidemiological and clinical aspects in a cohort of 1.306 Italian patients [in Italian]. Reumatismo. 2005;57(4):283–90.

    PubMed  CAS  Google Scholar 

  28. Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2197–223.

    Article  PubMed  Google Scholar 

  29. Parisi R, Symmons DP, Griffiths CE, Ashcroft DM, Identification and Management of Psoriasis and Associated ComorbidiTy (IMPACT) project team. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol. 2013;133(2):377–85.

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

The authors would like to acknowledge Caroline Spencer and Dr Sue Chambers (Rx Communications, Mold, UK) for medical writing assistance with the preparation of this manuscript, funded by Eli Lilly and Company.

Funding

This work was funded by Eli Lilly and Company.

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Correspondence to Elisabetta Cavallucci.

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Conflict of Interest

Veronica Rogai, Elisabetta Cavallucci and Alessandro Bitossi are employees and shareholders of Eli Lilly and Company. Volker Hammen is a former employee of Eli Lilly and Company. Fabrizio Cantini is a member of advisory boards for Eli Lilly. Francesca Prignano is a member of advisory boards and/or speaker for Eli Lilly, Abiogen Pharma, Abbvie, Novartis, Pfizer and Leo Pharma.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Psoriatic Arthritis

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Prignano, F., Rogai, V., Cavallucci, E. et al. Epidemiology of Psoriasis and Psoriatic Arthritis in Italy—a Systematic Review. Curr Rheumatol Rep 20, 43 (2018). https://doi.org/10.1007/s11926-018-0753-1

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  • DOI: https://doi.org/10.1007/s11926-018-0753-1

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