Abstract
Purpose of Review
Lumbar facet pain is generally considered to be one of the major causes of chronic low back pain. Each lumbar facet joint is innervated by the medial branch of the posterior spinal nerve from its own level and above. Radiofrequency (RF) of the medial branch of the posterior branch of the spinal nerve is an effective method for the treatment of lumbar facet pain. RF technology is diverse, including traditional radiofrequency (TRF), pulsed radiofrequency (PRF), cooled radiofrequency (CRF), low-temperature plasma radiofrequency ablation (CA), and other treatment methods. The purpose of this paper is to compare the efficacy of different radiofrequency techniques and to analyze the reasons for this in the context of anatomy.
Recent Findings
There have been studies confirming the differences in efficacy of different RF techniques. However, most of the studies only compared two RF techniques, not four techniques, TRF, CRF, PRF, and CA, and did not analyze the reasons for the differences in efficacy.
Summary
This article reviews the differences in the efficacy of the above four RF techniques, clarifies that the differences are mainly due to the inability to precisely localize the medial branch of the posterior branch of the spinal nerve, analyzes the reasons for the inability to precisely localize the posterior branch of the spinal nerve in conjunction with anatomy, and proposes that the development of RF technology for lumbar facet pain requires more in-depth anatomical, imaging, and clinical studies.
Similar content being viewed by others
Data Availability
No datasets were generated or analysed during the current study.
References
Vekaria R, et al. Intra-articular facet joint injections for low back pain: a systematic review. Eur Spine J. 2016;25(4):1266–81. https://doi.org/10.1007/s00586-016-4455-y.
Freburger JK, et al. The rising prevalence of chronic low back pain. Arch Intern Med. 2009;169(3):251–8. https://doi.org/10.1001/archinternmed.2008.543.
Gofeld M, Faclier G. Radiofrequency denervation of the lumbar zygapophysial joints–targeting the best practice. Pain Med. 2008;9(2):204–11. https://doi.org/10.1111/j.1526-4637.2007.00345.x.
Van Zundert J, et al. Evidence-based interventional pain medicine according to clinical diagnoses. Pain Pract. 2011;11(5):423–9. https://doi.org/10.1111/j.1533-2500.2011.00490.x.
Bogduk Pulsed radiofrequency. Pain Med. 2006;7(5):396–407. https://doi.org/10.1111/j.1526-4637.2006.00210.x.
Shuang F, et al. Clinical anatomy and measurement of the medial branch of the spinal dorsal ramus. Medicine (Baltimore). 2015;94(52): e2367. https://doi.org/10.1097/MD.0000000000002367.
Watanabe I, et al. Cooled-tip ablation results in increased radiofrequency power delivery and lesion size in the canine heart: importance of catheter-tip temperature monitoring for prevention of popping and impedance rise. J Interv Card Electrophysiol. 2002;6(1):9–16. https://doi.org/10.1023/a:1014140104777.
Trial C, et al. Coblation technology for surgical wound debridement: principle, experimental data, and technical data[J]. Int J Low Extrem Wounds. 2012;11(4):286–92.
Li SJ, Zhang SL, Feng D. A comparison of pulsed radiofrequency and radiofrequency denervation for lumbar facet joint pain. J Orthop Surg Res. 2023;18(1):331. https://doi.org/10.1186/s13018-023-03814-5.
McCormick ZL, et al. Randomized prospective trial of cooled versus traditional radiofrequency ablation of the medial branch nerves for the treatment of lumbar facet joint pain. Reg Anesth Pain Med. 2019;44(3):389–97. https://doi.org/10.1136/rapm-2018-000035.
Abra N, et al. Comparison of the clinical efficacy and safety of low-temperature plasma ablation and radiofrequency thermocoagulation in the treatment of low back pain of posterior spinal nerve branch origin [J]. Chin Med J. 2021;27(04):275–81.
Shih CL, et al. A comparison of efficacy among different radiofrequency ablation techniques for the treatment of lumbar facet joint and sacroiliac joint pain: a systematic review and meta-analysis. Clin Neurol Neurosurg. 2020;195: 105854. https://doi.org/10.1016/j.clineuro.2020.105854.
Tekin I, et al. A comparison of conventional and pulsed radiofrequency denervation in the treatment of chronic facet joint pain. Clin J Pain. 2007;23(6):524–9. https://doi.org/10.1097/AJP.0b013e318074c99c.
Candan B, Gungor S. Cooled-radiofrequency neurotomy for the treatment of chronic lumbar facet (zygapophyseal) joint pain: a retrospective study. Medicine (Baltimore). 2021;100(52): e28459. https://doi.org/10.1097/MD.0000000000028459.
Bogduk N, Wilson AS, Tynan W. The human lumbar dorsal rami. J Anat. 1982;134(Pt 2):383–97.
Pedersen HE, Blunck CF, Gardner E. The anatomy of lumbosacral posterior rami and meningeal branches of spinal nerve (sinu-vertebral nerves); with an experimental study of their functions. J Bone Joint Surg Am. 1956;38-A (2):377–91.
Suseki K, et al. Innervation of the lumbar facet joints. Origins and functions. Spine (Phila Pa 1976). 1997 ;22(5):477–85. https://doi.org/10.1097/00007632-199703010-00003.
Tessitore E, et al. Clinical evaluation and surgical decision making for patients with lumbar discogenic pain and facet syndrome. Eur J Radiol. 2015;84(5):765–70. https://doi.org/10.1016/j.ejrad.2014.03.016.
Chua NH, Vissers KC, Sluijter ME. Pulsed radiofrequency treatment in interventional pain management: mechanisms and potential indications-a review. Acta Neurochir (Wien). 2011;153(4):763–71. https://doi.org/10.1007/s00701-010-0881-5.
Cohen SP, Raja SN. Pathogenesis, diagnosis, and treatment of lumbar zygapophysial (facet) joint pain. Anesthesiology. 2007;106(3):591–614. https://doi.org/10.1097/00000542-200703000-00024.
Proietti L, et al. The impact of sagittal balance on low back pain in patients treated with zygoapophysial facet joint injection. Eur Spine J. 2014;23(Suppl 6):628–33. https://doi.org/10.1007/s00586-014-3559-5.
Kapetanakis S, Gkantsinikoudis N. Anatomy of lumbar facet joint: a comprehensive review. Folia Morphol (Warsz). 2021;80(4):799–805. https://doi.org/10.5603/FM.a2020.0122.
Kozera K, Ciszek B. Posterior branches of lumbar spinal nerves - part I: anatomy and functional importance. Ortop Traumatol Rehabil. 2016;18(1):1–10. https://doi.org/10.5604/15093492.1198827.
Demondion X, et al. The posterior lumbar ramus: CT-anatomic correlation and propositions of new sites of infiltration. AJNR Am J Neuroradiol. 2005;26(4):706–10.
Streetman D, et al. Endoscopic rhizotomy for facetogenic back pain: a review of the history, financial considerations, patient selection criteria, and clinical outcomes. World Neurosurg. 2023;169:36–41. https://doi.org/10.1016/j.wneu.2022.10.020.
Xue Y, et al. Endoscopic rhizotomy for chronic lumbar zygapophysial joint pain. J Orthop Surg Res. 2020;15(1):4. https://doi.org/10.1186/s13018-019-1533-y.
Moussa WM, Khedr W. Percutaneous radiofrequency facet capsule denervation as an alternative target in lumbar facet syndrome. Clin Neurol Neurosurg. 2016;150:96–104. https://doi.org/10.1016/j.clineuro.2016.09.004.
van Wijk RM, et al. Radiofrequency denervation of lumbar facet joints in the treatment of chronic low back pain: a randomized, double-blind, sham lesion-controlled trial. Clin J Pain. 2005;21(4):335–44. https://doi.org/10.1097/01.ajp.0000120792.69705.c9.
Cohen SP, et al. Effectiveness of lumbar facet joint blocks and predictive value before radiofrequency denervation: the Facet Treatment Study (FACTS), a randomized, controlled clinical trial. Anesthesiology. 2018;129(3):517–35. https://doi.org/10.1097/ALN.0000000000002274.
Jackson RP, Jacobs RR, Montesano PX. 1988 Volvo award in clinical sciences. Facet joint injection in low-back pain. A prospective statistical study. Spine (Phila Pa 1976). 1988;13(9):966–71. https://doi.org/10.1097/00007632-198809000-00002.
Schwarzer AC, et al. Clinical features of patients with pain stemming from the lumbar zygapophysial joints. Is the lumbar facet syndrome a clinical entity? Spine (Phila Pa 1976). 1994;19(10):1132–7. https://doi.org/10.1097/00007632-199405001-00006.
Bogduk N. International Spinal Injection Society guidelines for the performance of spinal injection procedures. Part 1: Zygapophysial joint blocks. Clin J Pain. 1997;13(4):285–302. https://doi.org/10.1097/00002508-199712000-00003.
Kvistad KA, Espeland A. Bildediagnostikk ved nakke- og ryggsmerter [Diagnostic imaging in neck and low back pain]. Tidsskr Nor Laegeforen. 2010;130(22):2256–9. Norwegian. https://doi.org/10.4045/tidsskr.09.1032.
Cohen SP, et al. Multicenter, randomized, comparative cost-effectiveness study comparing 0, 1, and 2 diagnostic medial branch (facet joint nerve) block treatment paradigms before lumbar facet radiofrequency denervation. Anesthesiology. 2010;113(2):395–405. https://doi.org/10.1097/ALN.0b013e3181e33ae5.
Schwarzer AC, et al. The false-positive rate of uncontrolled diagnostic blocks of the lumbar zygapophysial joints. Pain. 1994;58(2):195–200. https://doi.org/10.1016/0304-3959(94)90199-6.
Revel M, et al. Capacity of the clinical picture to characterize low back pain relieved by facet joint anesthesia. Proposed criteria to identify patients with painful facet joints. Spine (Phila Pa 1976). 1998;23(18):1972–6; discussion 1977. https://doi.org/10.1097/00007632-199809150-00011.
Manchikanti L, et al. The diagnostic validity and therapeutic value of lumbar facet joint nerve blocks with or without adjuvant agents. Curr Rev Pain. 2000;4(5):337–44. https://doi.org/10.1007/s11916-000-0016-4.
Hogan QH, Abram SE. Neural blockade for diagnosis and prognosis. A review Anesthesiology. 1997;86(1):216–41. https://doi.org/10.1097/00000542-199701000-00026.
Park KD, et al. Ultrasound versus fluoroscopy-guided cervical medial branch block for the treatment of chronic cervical facet joint pain: a retrospective comparative study. Skeletal Radiol. 2017;46(1):81–91. https://doi.org/10.1007/s00256-016-2516-2.
Wolter T, et al. Cryoneurolysis for zygapophyseal joint pain: a retrospective analysis of 117 interventions. Acta Neurochir (Wien). 2011;153(5):1011–9. https://doi.org/10.1007/s00701-011-0966-9.
Sehgal A, Valentine JM. Lumbar radiculopathy after zygapophyseal joint injection. Br J Anaesth. 2007;99(3):412–4. https://doi.org/10.1093/bja/aem178.
Cosman ER Jr, Dolensky JR, Hoffman RA. Factors that affect radiofrequency heat lesion size. Pain Med. 2014;15(12):2020–36. https://doi.org/10.1111/pme.12566.
Moon JY, et al. An alternative distal approach for the lumbar medial branch radiofrequency denervation: a prospective randomized comparative study. Anesth Analg. 2013;116(5):1133–40. https://doi.org/10.1213/ANE.0b013e31828b35fe.
Arıcı T, Kılıç E. Distal approach for percutaneous radiofrequency thermocoagulation of lumbar medial branches in patients with lumbar facet arthropathy: A retrospective analysis. Agri. 2020;32(1):31–37. English. https://doi.org/10.14744/agri.2019.15921.
Saito T, et al. Analysis of the posterior ramus of the lumbar spinal nerve: the structure of the posterior ramus of the spinal nerve. Anesthesiology. 2013;118(1):88–94. https://doi.org/10.1097/ALN.0b013e318272f40a.
Saito T, et al. Third primary branch of the posterior ramus of the spinal nerve at the thoracolumbar region: a cadaveric study. Surg Radiol Anat. 2019;41(8):951–61. https://doi.org/10.1007/s00276-019-02258-z.
Bogduk N, editor. Practice guidelines for spinal diagnostic and treatment procedures. Lumbar Medial Branch Blocks: International Spine Intervention Society; 2013. p. 559–99.
Cedeno DL, et al. Comparisons of lesion volumes and shapes produced by a radiofrequency system with a cooled, a protruding, or a monopolar probe. Pain Physician. 2017;20(6):E915–22.
Yin, et al. Factors influencing the efficacy of radiofrequency ablation of the medial branch of the spinal nerve in the treatment of lower back pain [J]. J Vasc Interv Radiol. 2022;31(03):263–266.
Ballantyne JC, Mao J. Opioid therapy for chronic pain. N Engl J Med. 2003;349(20):1943–53. https://doi.org/10.1056/NEJMra025411.
Stelzer W, et al. Influence of BMI, gender, and sports on pain decrease and medication usage after facet-medial branch neurotomy or SI joint lateral branch cooled RF-neurotomy in case of low back pain: original research in the Austrian population. J Pain Res. 2017;10:183–90. https://doi.org/10.2147/JPR.S121897.
Çetin A, Yektaş A. Evaluation of the short- and long-term effectiveness of pulsed radiofrequency and conventional radiofrequency performed for medical branch block in patients with lumbar facet joint pain. Pain Res Manag. 2018;2018:7492753. https://doi.org/10.1155/2018/7492753.
Kroll HR, et al. A randomized, double-blind, prospective study comparing the efficacy of continuous versus pulsed radiofrequency in the treatment of lumbar facet syndrome. J Clin Anesth. 2008;20(7):534–7. https://doi.org/10.1016/j.jclinane.2008.05.021.
Chen YS, et al. Radiofrequency denervation on lumbar facet joint pain in the elderly: a randomized controlled prospective trial. Pain Physician. 2022;25(8):569–76.
Conger A, et al. The effectiveness of radiofrequency ablation of medial branch nerves for chronic lumbar facet joint syndrome in patients selected by guideline-concordant dual comparative medial branch blocks. Pain Med. 2020;21(5):902–9. https://doi.org/10.1093/pm/pnz248.
Sansone P, et al. Pulsed radiofrequency for lumbar facet joint pain: a viable therapeutic option. A retrospective observational study. Pain Ther. 2020;9(2):573–82. https://doi.org/10.1007/s40122-020-00187-z.
Medina-Pérez JJ, et al. Cooled radiofrequency treatment for radicular pain related to lumbar disc herniation. Cureus. 2023;15(9): e46255. https://doi.org/10.7759/cureus.46255.
Xue, et al. Low-temperature plasma radiofrequency ablation for low back pain of posterior spinal nerve branch origin [J]. Chin J Orthop. 2019;27(09):850–852.
Funding
This study was supported by the Jilin Provincial Subject Fund (No. YDZJ202201ZYTS208).
Author information
Authors and Affiliations
Contributions
Y.T.S. prepared the images, L.N.Q., J.H.Y. and Y.R.Y. contributed to the concept and design of the study. The original manuscript was written by L.N.Q., and X.Z.Q. and Y.S. commented on previous versions of the original manuscript. All authors read and approved the final draft.
Corresponding author
Ethics declarations
Conflict of Interest
The authors declare no conflict of interests.
Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Research Involving Human Participants and/or Animals
This article does not contain any studies with human or animal subjects performed by any of the authors.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Qi, L.N., Sun, Y., Shi, Y.T. et al. Comparison of the Efficacy of Different Radiofrequency Techniques for the Treatment of Lumbar Facet Joint Pain: Combined with Anatomy. Curr Pain Headache Rep (2024). https://doi.org/10.1007/s11916-024-01241-7
Accepted:
Published:
DOI: https://doi.org/10.1007/s11916-024-01241-7