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Interventional Therapies for Pain in Cancer Patients: a Narrative Review

  • Alternative Treatments for Pain Medicine (M Jones, section Editor)
  • Published:
Current Pain and Headache Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Pain is a prevalent symptom in the lives of patients with cancer. In light of the ongoing opioid epidemic and increasing awareness of the potential for opioid abuse and addiction, clinicians are progressively turning to interventional therapies. This article reviews the interventional techniques available to mitigate the debilitating effects that untreated or poorly treated pain have in this population.

Recent Findings

A range of interventional therapies and technical approaches are available for the treatment of cancer-related pain. Many of the techniques described may offer effective analgesia with less systemic toxicity and dependency than first- and second-line oral and parenteral agents. Neuromodulatory techniques including dorsal root ganglion stimulation and peripheral nerve stimulation are increasingly finding roles in the management of oncologic pain.

Summary

The goal of this pragmatic narrative review is to discuss interventional approaches to cancer-related pain and the potential of such therapies to improve the quality of life of cancer patients.

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Authors and Affiliations

  1. Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    David Hao & Juan Cotte

  2. Department of Neurology, Northwell Health – North Shore University Hospital/LIJ, Hofstra School of Medicine, Manhasset, NY, USA

    Shawn Sidharthan

  3. Harvard Medical School, Boston, MA, USA

    Mary Decker

  4. Division of Pain Medicine, Department of Anesthesia, University of Pittsburgh Medical Center, Susquehanna, Williamsport, PA, USA

    Mariam Salisu-Orhurhu & Vwaire Orhurhu

  5. Department of Anesthesiology and Perioperative Medicine, Division of Pain Medicine, Mayo Clinic, Rochester, MN, USA

    Dare Olatoye

  6. Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX, USA

    Jay Karri & Jonathan M. Hagedorn

  7. Department of Anesthesia, Critical Care and Pain Medicine, Division of Pain Medicine, Johns Hopkins Hospital, Baltimore, MD, USA

    Peju Adekoya

  8. Department of Orthopaedics and Rehabilitation, Division of Physiatry, Yale School of Medicine, Yale New Haven Hospital, New, Haven, CT, USA

    Charles Odonkor

  9. Division of Pain Medicine, Department of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York City, NY, USA

    Amitabh Gulati

Authors
  1. David Hao
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  2. Shawn Sidharthan
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  3. Juan Cotte
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  4. Mary Decker
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  5. Mariam Salisu-Orhurhu
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  6. Dare Olatoye
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  7. Jay Karri
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  8. Jonathan M. Hagedorn
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  9. Peju Adekoya
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  10. Charles Odonkor
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  11. Amitabh Gulati
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  12. Vwaire Orhurhu
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Corresponding author

Correspondence to David Hao.

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This article is part of the Topical Collection on Alternative Treatments for Pain Medicine

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Hao, D., Sidharthan, S., Cotte, J. et al. Interventional Therapies for Pain in Cancer Patients: a Narrative Review. Curr Pain Headache Rep 25, 44 (2021). https://doi.org/10.1007/s11916-021-00963-2

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