Skip to main content

Advertisement

Log in

Migraine Management in Children

  • Headache (RB Halker, Section Editor)
  • Published:
Current Neurology and Neuroscience Reports Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

Migraine management in children relies on understanding the difference between adult and childhood migraine, being able to identify childhood migraine variants and knowledge of both the pediatric and adult literature regarding treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Levin M. The international classification of headache disorders, 3rd edition (ICHD III)—changes and challenges. Headache: J Head Face Pain. 2013;53:1383–95. doi:10.1111/head.12189.

    Article  Google Scholar 

  2. Cologno D, Torelli P, Manzoni GC. Migraine with aura: a review of 81 patients at 10–20 years’ follow-up. Cephalalgia. 1998;18:690–6.

    Article  CAS  PubMed  Google Scholar 

  3. Lewis D, Ashwal S, Hershey A, Hirtz D, Yonker M, Silberstein S. Practice parameter: pharmacological treatment of migraine headache in children and adolescents. Neurology. 2004;63:2215–24.

    Article  CAS  PubMed  Google Scholar 

  4. Hershey AD, Powers SW, Bentti AL, et al. Standard dosing of amitriptyline is highly effective in a pediatric headache center population. Headache. 1999;39:357–8.

    Google Scholar 

  5. Winner P, Pearlman EM, et al. Topiramate for migraine prevention in children: a randomized, double-blind, placebo-controlled trial. Headache. 2005;45(10):1304–12.

    Article  PubMed  Google Scholar 

  6. Lewis D, Winner P, et al. Randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of topiramate for migraine prevention in pediatric subjects 12 to 17 years of age. Pediatrics. 2009;123(3):924–34.

    Article  PubMed  Google Scholar 

  7. Bakola E, Skapinakis P, Tzoufi M, Damigos D, Mavreas V. Anticonvulsant drugs for pediatric migraine prevention: an evidence-based review. Eur J Pain. 2009;13(9):893–901.

    Article  CAS  PubMed  Google Scholar 

  8. Caruso JM, Brown WD, et al. The efficacy of divalproex sodium in the prophylactic treatment of children with migraine. Headache. 2000;40(8):672–6.

    Article  CAS  PubMed  Google Scholar 

  9. Serdaroglu G, Erhan E, et al. Sodium valproate prophylaxis in childhood migraine. Headache. 2002;42(8):819–22.

    Article  PubMed  Google Scholar 

  10. Apostol G, Cady RK, et al. Divalproex extended-release in adolescent migraine prophylaxis: results of a randomized, double-blind, placebo-controlled study. Headache. 2008;48(7):1012–25.

    Article  PubMed  Google Scholar 

  11. Mulleners WM, McCrory DC, Linde M. Antiepileptics in migraine prophylaxis: An updated Cochrane review. Cephalalgia. 2014. Evaluated the efficacy of anticonvulsants used in the migraine population and the evidence supporting their use.

  12. Buse D, Manack A, Fanning K, Serrano D, Reed M, Turkel C, et al. Chronic migraine prevalence, disability, and socioeconomic factors: results from the American Migraine Prevalence and Prevention Study. Headache. 2012;52:1456–70. Demonstrates the difficulties this condition places on each individual patient. Children missing school are also missing social experiences as well as learning opportunies.

    Article  PubMed  Google Scholar 

  13. Diener HC, Dodick DW, Aurora SK, et al. OnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 2 trial. Cephalalgia. 2010;30(7):804–14.

    Article  CAS  PubMed  Google Scholar 

  14. Bigal M, Rapoport A, Sheftell F, et al. The International Classification of Headache Disorders revised criteria for chronic migraine – field testing in a headache specialty clinic. Cephalalgia 2007;230–234.

  15. Chan V, Mccabe J, MacGregor D. Botox treatment for migraine and chronic daily headache in adolescents. J Neurosc Nurs. 2009;41(5):235–43.

    Article  Google Scholar 

  16. Ahmed K, Oas K, Mack K, Garza I. Experience with botulinum toxin type A in medically intractable pediatric chronic daily headache. Pediatr Neurol. 2010;43:316–9.

    Article  PubMed  Google Scholar 

  17. Bernhard MK, Bertsche A, Syrbe S, Weise S, Merkenschlager A. Botulinum toxin injections for chronic migraine in adolescents—an early therapeutic option in the transition from neuropaediatrics to neurology. Fortschr Neurol Psychiatr. 2014;82(1):39–42. This is a promising treatment for the pediatric population with chronic migraine. It has been approved in adults and is now being also included in the pediatric population.

    Article  CAS  PubMed  Google Scholar 

  18. Kabbouche M, O’Brien H, Hershey AD. Onabotulinum toxin A in pediatric chronic daily headache. Curr Neurol Neurosci Rep. 2012;12:114–7.

    Article  CAS  PubMed  Google Scholar 

  19. Arruda MA, Guidetti V, Galli F, et al. Primary headaches in childhood—a population-based study. Cephalalgia. 2010;30:1056–64.

    Article  PubMed  Google Scholar 

  20. Fleisher DR. Cyclic vomiting syndrome and migraine. J Pediatr. 1999;134:533–5.

    Article  CAS  PubMed  Google Scholar 

  21. Moses J, Keilman A, Worley S, Radhakrishnan K, Rothner AD, Parikh S. Approach to the diagnosis and treatment of cyclic vomiting syndrome: a large single-center experience with 106 patients. Pediatr Neurol. 2014;50(6):569–73. Improved understanding of timing of onset and details abnormal lab values that suggest related abnormalities that these patients have which may lead to better understanding and therefore improve treatment.

    Article  PubMed  Google Scholar 

  22. Farquar HA. Abdominal migraine in children. BMJ. 1956;i:1082–5.

    Article  Google Scholar 

  23. Russell G et al. Abdominal migraine: evidence for existence and treatment options. Pediatr Drugs. 2002;4:1–8.

    Article  Google Scholar 

  24. Drigo P, Carli G, Laverda AM. Benign paroxysmal vertigo of childhood. Brain Dev (Netherlands). 2001;23:38–41.

    Article  CAS  Google Scholar 

  25. Worawattanakul M et al. Abdominal migraine: prophylactic treatment and follow-up. J Pediatr Gastroenerol Nutr. 1999;28:37–49.

    Article  CAS  Google Scholar 

  26. Drigo P, Carli G, Laverda AM. Benign paroxysmal torticollis of infancy. Brain Dev. 2000;22:169–72.

    Article  CAS  PubMed  Google Scholar 

  27. Herman MJ. Torticollis in infants and children: common and unusual causes. Instr Course Lect. 2006;55:647–53.

    PubMed  Google Scholar 

Download references

Compliance with Ethics Guidelines

Conflict of Interest

Tara Mangum declares that she has no conflict of interest. Marcy Yonker has received consultancy fees from Amgen and grants from NINDS, Allergan, and Astra-Zeneca.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Marcy Yonker.

Additional information

This article is part of the Topical Collection on Headache

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yonker, M., Mangum, T. Migraine Management in Children. Curr Neurol Neurosci Rep 15, 20 (2015). https://doi.org/10.1007/s11910-015-0540-6

Download citation

  • Published:

  • DOI: https://doi.org/10.1007/s11910-015-0540-6

Keywords

Navigation