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Secondary Sclerosing Cholangitis: a Review of Recent Literature

  • Pancreas and Biliary Tract (S Haluszka, Section Editor)
  • Published:
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Abstract

Purpose of Review

Secondary sclerosing cholangitis is an emerging entity. Yet, because of the low incidence and varying etiologies of this disease, the literature is not robust. There are mainly case reports and small studies evaluating the disease. Our aim in this review is to bring the reader up to date with recent literature on secondary sclerosing cholangitis including the disease presentation, course, prognosis, and treatment options.

Recent Findings

Numerous case reports have been published the last 5 years on secondary sclerosing cholangitis. We have divided them into infectious, drug-induced, ischemic, obstructive, and autoimmune etiologies. The bulk of the literature describes secondary sclerosing cholangitis in the critically ill patient.

Summary

Secondary sclerosing cholangitis due to drugs or autoimmune causes seem to have the best prognosis. However, causes such as critical illness seem to have worse outcomes.

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References

Papers of particular interest, published recently, have been highlighted as: • Of mportance

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Authors and Affiliations

  1. Division of Gastroenterology, University of Arizona, Tucson, AZ, USA

    John Brooling

  2. Division of Gastroenterology, Southern Arizona VA Hospital, 3601 S 6th Ave, Tucson, AZ, 85723, USA

    Rolando Leal

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  1. John Brooling
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  2. Rolando Leal
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Correspondence to Rolando Leal.

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Rolando Leal and John Brooling declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Pancreas and Biliary Tract

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Brooling, J., Leal, R. Secondary Sclerosing Cholangitis: a Review of Recent Literature. Curr Gastroenterol Rep 19, 44 (2017). https://doi.org/10.1007/s11894-017-0583-8

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  • DOI: https://doi.org/10.1007/s11894-017-0583-8

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