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The PASCAL Device—Early Experience with a Leaflet Approximation Device: What Are the Benefits/Limitations Compared with the MitraClip?

  • Structural Heart Disease (RJ Siegel and NC Wunderlich, Section Editors)
  • Published:
Current Cardiology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

This review article describes the technical features of the novel Edwards PASCAL transcatheter valve repair system as well as the evidence accumulated so far.

Recent Findings

Transcatheter mitral and tricuspid valve leaflet approximation enable treatment of patients with mitral and tricuspid regurgitation who are not eligible for surgery. The PASCAL device offers an alternative that may allow to overcome some of the limitations of previous systems and open the path for an approach adapted to individual patient’s anatomy. Early data show similar safety and efficacy compared with the Abbott MitraClip system.

Summary

The PASCAL system is a valuable addition to the armamentarium of transcatheter mitral and tricuspid valve repair devices. Randomized head-to-head comparisons and long-term data are needed to confirm the promising results observed so far.

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Authors and Affiliations

  1. Department of Cardiology, Bern University Hospital, University of Bern, 3010, Bern, Switzerland

    Noé Corpataux, Mirjam Gauri Winkel, Mohammad Kassar, Nicolas Brugger, Stephan Windecker & Fabien Praz

Authors
  1. Noé Corpataux
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  2. Mirjam Gauri Winkel
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  3. Mohammad Kassar
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  4. Nicolas Brugger
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  5. Stephan Windecker
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  6. Fabien Praz
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Corresponding author

Correspondence to Fabien Praz.

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Conflict of Interest

Stephan Windecker reports Institutional research and education grants from Amgen, Abbott, Bayer, BMS, CSL Behring, Boston Scientific, Biotronik, Medtronic, Edwards Lifesciences, Polares, and Sinomed.

Noé Corpataux, Mirjam Gauri Winkel, Mohammad Kassar, Nicolas Brugger, and Fabien Praz declare that they have no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Structural Heart Disease

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Corpataux, N., Winkel, M.G., Kassar, M. et al. The PASCAL Device—Early Experience with a Leaflet Approximation Device: What Are the Benefits/Limitations Compared with the MitraClip?. Curr Cardiol Rep 22, 74 (2020). https://doi.org/10.1007/s11886-020-01305-1

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  • DOI: https://doi.org/10.1007/s11886-020-01305-1

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