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Outcomes for Intermittent Neuromodulation as a Treatment for Overactive Bladder

  • Overactive Bladder (U Lee, Section Editor)
  • Published:
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Abstract

Purpose of Review

In this review, we describe the history and basic science behind intermittent neuromodulation, specifically of the tibial nerve and its neuroanatomic suitability for this approach, as well as the logistics, efficacy, and advantages of peripheral tibial nerve stimulation (PTNS) in both idiopathic and neurogenic overactive bladder (OAB) populations. We also discuss the less commonly used sacral, pudendal, and genital nerves as a means of intermittent neuromodulation for the management of OAB.

Recent Findings

Intermittent neuromodulation in the form of PTNS is approved as a third-line treatment of OAB, which affects upwards of 16% of the population of the USA.

Summary

Several studies and clinical trials have demonstrated the effectiveness of PTNS in treating OAB, with the benefit of decreased cost and invasiveness compared to chronic, implantable neurostimulators. This has been explored in various patient populations including patients with idiopathic and neurogenic detrusor overactivity.

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Papers of particular interest, published recently, have been highlighted as: • Of importance

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Authors and Affiliations

  1. Department of Urology, Beaumont Health Systems, 31157 Woodward Avenue, Royal Oak, MI, 48073, USA

    Laura N. Nguyen & Jason P. Gilleran

  2. Department of Urology, Detroit Medical Center, Detroit, MI, 48201, USA

    M. Lira Chowdhury

  3. Oakland University William Beaumont School of Medicine, Rochester, MI, 48309, USA

    Jason P. Gilleran

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  1. Laura N. Nguyen
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  2. M. Lira Chowdhury
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  3. Jason P. Gilleran
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Correspondence to Jason P. Gilleran.

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Drs. Nguyen, Chowdhury, and Gilleran declare no conflicts of interest.

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This article is part of the Topical Collection on Overactive Bladder

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Nguyen, L.N., Chowdhury, M.L. & Gilleran, J.P. Outcomes for Intermittent Neuromodulation as a Treatment for Overactive Bladder. Curr Bladder Dysfunct Rep 12, 66–73 (2017). https://doi.org/10.1007/s11884-017-0411-x

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