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How to Assess, Control, and Manage Uncontrolled CRS/Nasal Polyp Patients

  • Rhinosinusitis (J Mullol, Section Editor)
  • Published:
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Abstract

Purpose of Review

Chronic rhinosinusitis (CRS) is a multidimensional inflammatory disorder of the nose and paranasal sinuses. We reviewed the recent literature to identify improved methods to assess, control, and manage these difficult to control patients.

Recent Findings

The role of endotyping in CRS has offered a better understanding of the underlying pathophysiology and allows for more targeted treatment. The understanding of systemic disorders and their role in CRS and the importance of topical treatment reaching the sinuses has also allowed for better control of these patients.

Summary

We have provided some of the commonly identified causes for uncontrolled CRS and a sensible approach to assessing these patients. We have also focused on common areas of pitfalls in the surgery and choice of patients and the role for ongoing systemic treatment. The future of managing this difficult condition includes endotyping using inflammatory markers and individualizing the treatment to the patient by using specific monoclonal antibodies.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Rhinology and Skull Base, Macquarie University, Sydney, Australia

    Rahuram Sivasubramaniam & Richard J. Harvey

  2. Sydney ENT Clinic, 67 Burton Street, Darlinghurst, NSW, 2010, Australia

    Richard J. Harvey

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  1. Rahuram Sivasubramaniam
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Correspondence to Richard J. Harvey.

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Conflict of Interest

Dr. Harvey reports personal fees from Medtronic, Olympus, Neilmed, Seqiris, Teva, and Astrazeneca. Dr. Sivasubramaniam declares no conflicts of interest relevant to this manuscript.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Rhinosinusitis

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Sivasubramaniam, R., Harvey, R.J. How to Assess, Control, and Manage Uncontrolled CRS/Nasal Polyp Patients. Curr Allergy Asthma Rep 17, 58 (2017). https://doi.org/10.1007/s11882-017-0728-8

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