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The prevalence of depression in patients living with implantable cardioverter defibrillator: a systematic review and meta-analysis

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Abstract

Abstract

Depression is a common disorder in patients with implantable cardioverter defibrillator (ICD). There are a variety of studies estimated the prevalence of depression in these patients. The present study aimed to investigate the prevalence of depression in patients with ICD.

Methods

In the present study, we conducted a systematic review of studies published in PubMed, Scopus, Web of Science (WoS), Medline, and EMBASE without any time filtration to obtain studies investigated the prevalence of depression in patients with ICD. Search terms consisted of “Implantable Cardioverter Defibrillator(s)” in combination with “depression,” “depressive,” “prevalence,” “implanted cardioverter,” “implantable,” and “implantable defibrillator.”

Results

We identified 15 relevant studies, comprising data from 10,182 patients with ICD from whom 2400 (23.58%) (95% CI, 15.36–31.79) had depression. The results of the subgroup analysis showed that the prevalence of depression among middle-aged patients (28.58% with confidence interval of 95%, 21.51–35.65) was higher than elderly patients (22.23% with confidence interval of 95%, 11.21–33.24) and it was not significantly correlated with the mean age of samples (P = 0.255), sample size (P = 0.686), and the publication date (P = 0.784), although there was a significant correlation between the prevalence of depression and the quality of articles so that the prevalence was decreasing with an increase in the quality (P = 0.046).

Conclusion

Around 1 in 4 patients with ICD (23.58%) experiences depression progression after an ICD placement. This prevalence is comparable to that in the general population, and close to that of the patients with common chronic diseases.

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Authors and Affiliations

  1. Mother and Child Care Research Center, Nursing and Midwifery School, Hamadan University of Medical Sciences, Hamadan, Iran

    Khodayar Oshvandi, Mahnaz Khatiban & Mohammadreza Razavi

  2. Department of Nursing, School of Nursing and Midwifery, Kurdistan University of Medical Sciences, Sanandaj, Iran

    Reza Ghanei Gheshlagh

  3. Clinical Care Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran

    Reza Ghanei Gheshlagh

  4. Nursing and Midwifery School, Hamadan University of Medical Sciences, Blvd. Shahid Fahmideh, Hamadan, Iran

    Mohammadreza Razavi

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  1. Khodayar Oshvandi
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Substantial contributions to the conception or design of the work: Mohammadreza Razavi, Khodayar Oshvandi, and Mahnaz Khatiban. Acquisition, analysis, or interpretation of data for the work: Mohammadreza Razavi and Reza Ghanei Gheshlagh. Drafting the work or revising it critically for important intellectual content: Mohammadreza Razavi, Khodayar Oshvandi, and Mahnaz Khatiban. Final approval of the version to be published: Mohammadreza Razavi, Khodayar Oshvandi, and Mahnaz Khatiban. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: Mohammadreza Razavi, Khodayar Oshvandi, Mahnaz Khatiban, and Reza Ghanei Gheshlagh.

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Oshvandi, K., Khatiban, M., Ghanei Gheshlagh, R. et al. The prevalence of depression in patients living with implantable cardioverter defibrillator: a systematic review and meta-analysis. Ir J Med Sci 189, 1243–1252 (2020). https://doi.org/10.1007/s11845-020-02208-4

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