Skip to main content

Advertisement

Log in

Patients referred for arteriovenous fistula construction: a retrospective outcome analysis

  • Original Article
  • Published:
Irish Journal of Medical Science (1971 -) Aims and scope Submit manuscript

Abstract

Objectives

With lower rates of sepsis and re-interventions, arteriovenous fistula (AVF) is the preferred vascular access modality. The aim of this study is to evaluate the outcomes of patients referred for AVF construction at a single center in Cork, Ireland.

Methods

The current study is a single-center retrospective review of all patients who underwent AVF creation between 2015 and 2017. Additionally, the kidney disease clinical patient management system was used to provide statistics on AVF use in Ireland.

Results

39.3% of hemodialysis patients in Ireland use an AVF for vascular access. Regional use ranged from 50 to 20% across Irish hemodialysis centers. At Cork University Hospital, 192 AVFs were created. The population was 69.3% male (n = 133), 30.7% female (n = 59) with a mean (±SEM) age of 58.8 ± 1.03 years. 69.5% of females received a brachiocephalic AVF (BCAVF) while 13.6% had a radiocephalic AVF (RCAVF) constructed. Significance was seen when comparing gender and AVF type (p < 0.001). Fifty-four percent of the fistulae were brachiocephalic (n = 103), 33% were radiocephalic (n = 63), and 4% were brachiobasilic (n = 8). BCAVF patients (62.7 ± 1.2 years) were significantly older than patients receiving a RCAVF (54.5 ± 1.9 years, p < 0.001). A post-operative thrill or continuous flow on Doppler was present in 99% of patients (n = 190) with maturation and complication rates of 82.7% (n = 153) and 5.7% (n = 11) respectively. 69.9% of AVFs were needled for hemodialysis (n = 114).

Conclusions

AVF outcomes at this center are consistent with reported statistics in the literature. Patient age, sex, and diabetic status may influence the use of proximal AVF. AVF creation rates in Ireland are below international reported recommendations.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

Abbreviations

AVF:

Arteriovenous fistula

AVG:

Arteriovenous graft

BCAVF:

Brachiocephalic AVF

CKD:

Chronic kidney disease

CVC:

Central venous catheter

HD:

Hemodialysis

KDOQI:

Kidney Disease Outcomes Quality Initiative

RCAVF:

Radiocephalic AVF

RRT:

Renal replacement therapy

References

  1. Kimball TA, Barz K, Dimond KR, Edwards JM, Nehler MR (2011) Efficiency of the kidney disease outcomes quality initiative guidelines for preemptive vascular access in an academic setting. J Vasc Surg 54:760–765. https://doi.org/10.1016/j.jvs.2011.03.006

    Article  PubMed  Google Scholar 

  2. Arora P, Vasa P, Brenner D, Iglar K, McFarlane P, Morrison H, Badawi A (2013) Prevalence estimates of chronic kidney disease in Canada: results of a nationally representative survey. CMAJ 185:E417–E423. https://doi.org/10.1503/cmaj.120833

    Article  PubMed  PubMed Central  Google Scholar 

  3. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, van Lente F, Levey AS (2007) Prevalence of chronic kidney disease in the United States. JAMA 298:2038–2047. https://doi.org/10.1001/jama.298.17.2038

    Article  CAS  PubMed  Google Scholar 

  4. Stack AG, Casserly LF, Cronin CJ, Chernenko T, Cullen W, Hannigan A, Saran R, Johnson H, Browne G, Ferguson JP (2014) Prevalence and variation of chronic kidney disease in the Irish health system: initial findings from the National Kidney Disease Surveillance Programme. BMC Nephrol 15:2038–2012. https://doi.org/10.1186/1471-2369-15-185

    Article  Google Scholar 

  5. International Society of Nephrology (2014) Kidney Health for Life report maps: CKD multinational inventory, 2014. Int Soc Nephrol 76–83

  6. Sinnakirouchenan R, Holley JL (2011) Peritoneal dialysis versus hemodialysis: risks, benefits, and access issues. Adv Chronic Kidney Dis 18:428–432. https://doi.org/10.1053/j.ackd.2011.09.001

    Article  PubMed  Google Scholar 

  7. Irish Kidney Association (2018) Irish Kidney Association: support magazine, spring 2018. Irish Kidney Association Support Magazine 10–12

  8. Perl J, Nessim SJ, Moist LM, Wald R, Na Y, Tennankore KK, Chan CT (2016) Vascular access type and patient and technique survival in home hemodialysis patients: the Canadian Organ Replacement Register. Am J Kidney Dis 67:251–259. https://doi.org/10.1053/j.ajkd.2015.07.032

    Article  PubMed  Google Scholar 

  9. Vascular Access 2006 Work Group (2006) Clinical practice guidelines for vascular access. Am J Kidney Dis 48(Suppl 1):S176–S247. https://doi.org/10.1053/j.ajkd.2006.04.029

    Article  Google Scholar 

  10. Ravani P, Palmer SC, Oliver MJ, Quinn RR, MacRae JM, Tai DJ, Pannu NI, Thomas C, Hemmelgarn BR, Craig JC, Manns B, Tonelli M, Strippoli GFM, James MT (2013) Associations between hemodialysis access type and clinical outcomes: a systematic review. J Am Soc Nephrol 24:465–473. https://doi.org/10.1681/ASN.2012070643

    Article  PubMed  PubMed Central  Google Scholar 

  11. (2001) III. NKF-K/DOQI clinical practice guidelines for vascular sccess: update 2000. Am J Kidney Dis 37:S137–81. https://doi.org/10.1016/S0272-6386(01)70007-8

  12. Ethier J, Mendelssohn DC, Elder SJ, Hasegawa T, Akizawa T, Akiba T, Canaud BJ, Pisoni RL (2008) Vascular access use and outcomes: an international perspective from the Dialysis Outcomes and Practice Patterns Study. Nephrol Dial Transplant 23:3219–3226. https://doi.org/10.1093/ndt/gfn261

    Article  PubMed  PubMed Central  Google Scholar 

  13. Lee T, Barker J, Allon M (2005) Tunneled catheters in hemodialysis patients: reasons and subsequent outcomes. Am J Kidney Dis 46:501–508. https://doi.org/10.1053/j.ajkd.2005.05.024

    Article  PubMed  Google Scholar 

  14. Floege J, Gillespie IA, Kronenberg F, Anker SD, Gioni I, Richards S, Pisoni RL, Robinson BM, Marcelli D, Froissart M, Eckardt KU (2015) Development and validation of a predictive mortality risk score from a European hemodialysis cohort. Kidney Int 87:996–1008. https://doi.org/10.1038/ki.2014.419

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Allon M, Daugirdas J, Depner TA, Greene T, Ornt D, Schwab SJ (2006) Effect of change in vascular access on patient mortality in hemodialysis patients. Am J Kidney Dis 47:469–477. https://doi.org/10.1053/j.ajkd.2005.11.023

    Article  PubMed  Google Scholar 

  16. Hussein WF, Mohammed H, Browne L, Plant L, Stack AG (2018) Prevalence and correlates of central venous catheter use among haemodialysis patients in the Irish health system - a national study. BMC Nephrol 19:76. https://doi.org/10.1186/s12882-018-0873-x

    Article  PubMed  PubMed Central  Google Scholar 

  17. Leake AE, Yuo TH, Wu T, Fish L, Dillavou ED, Chaer RA, Leers SA, Makaroun MS (2015) Arteriovenous grafts are associated with earlier catheter removal and fewer catheter days in the United States Renal Data System population. J Vasc Surg 62:123–127. https://doi.org/10.1016/j.jvs.2015.02.018

    Article  PubMed  Google Scholar 

  18. de Leur K, Öztürk Ç, Zeeland MLPV et al (2013) Vascular access outcome in the elderly dialysis patient in combination with the quality of life. Vasc Endovasc Surg 47:444–448. https://doi.org/10.1177/1538574413495464

    Article  Google Scholar 

  19. Korepta LM, Watson JJ, Elder EA, Davis AT, Mansour MA, Chambers CM, Cuff RF, Wong PY (2016) Outcomes for forearm and upper arm arteriovenous fistula creation with the transposition technique. J Vasc Surg 63:764–771. https://doi.org/10.1016/j.jvs.2015.09.049

    Article  PubMed  Google Scholar 

  20. Dember LM, Beck GJ, Allon M, Delmez JA, Dixon BS, Greenberg A, Himmelfarb J, Vazquez MA, Gassman JJ, Greene T, Radeva MK, Braden GL, Ikizler TA, Rocco MV, Davidson IJ, Kaufman JS, Meyers CM, Kusek JW, Feldman HI, Dialysis Access Consortium Study Group (2008) Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis. A randomized controlled trial. JAMA 299:2164–2171. https://doi.org/10.1001/jama.299.18.2164

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Al-Jaishi AA, Oliver MJ, Thomas SM et al (2014) Patency rates of the arteriovenous fistula for hemodialysis: a systematic review and meta-analysis. Am J Kidney Dis 63:464–478. https://doi.org/10.1053/j.ajkd.2013.08.023

    Article  PubMed  Google Scholar 

  22. Wilmink T, Hollingworth L, Powers S, Allen C, Dasgupta I (2016) Natural history of common autologous arteriovenous fistulae: consequences for planning of dialysis access. Eur J Vasc Endovasc Surg 51:134–140. https://doi.org/10.1016/j.ejvs.2015.10.005

    Article  CAS  PubMed  Google Scholar 

  23. Biuckians A, Scott EC, Meier GH, Panneton JM, Glickman MH (2008) The natural history of autologous fistulas as first-time dialysis access in the KDOQI era. J Vasc Surg 47:415–421. https://doi.org/10.1016/j.jvs.2007.10.041

    Article  PubMed  Google Scholar 

  24. Motulsky H (1999) Analyzing data with GraphPad prism. GraphPad Software Incorporated, San Diego, CA

  25. Hakaim AG, Nalbandian M, Scott T (1998) Superior maturation and patency of primary brachiocephalic and transposed basilic vein arteriovenous fistulae in patients with diabetes. YMVA 27:154–157

    CAS  Google Scholar 

  26. McGrogan D, Shakarchi Al J, Khawaja A et al (2015) Arteriovenous fistula outcomes in the elderly. J Vasc Surg 62:1652–1657. https://doi.org/10.1016/j.jvs.2015.07.067

    Article  PubMed  Google Scholar 

  27. Masengu A, McDaid J, Maxwell AP, Hanko JB (2016) Preoperative radial artery volume flow is predictive of arteriovenous fistula outcomes. J Vasc Surg 63:429–435. https://doi.org/10.1016/j.jvs.2015.08.106

    Article  PubMed  Google Scholar 

  28. Lee JH, Won JH, Oh CK, Jung HA (2012) Clinical significance of upper-arm cephalic vein patency in autogenous radial-cephalic wrist fistulas for hemodialysis. Eur J Vasc Endovasc Surg 44:514–520. https://doi.org/10.1016/j.ejvs.2012.08.017

    Article  CAS  PubMed  Google Scholar 

  29. Weale AR, Bevis P, Neary WD, Boyes S, Morgan JD, Lear PA, Mitchell DC (2008) Radiocephalic and brachiocephalic arteriovenous fistula outcomes in the elderly. J Vasc Surg 47:144–150. https://doi.org/10.1016/j.jvs.2007.09.046

    Article  PubMed  Google Scholar 

  30. Schinstock CA, Albright RC, Williams AW, Dillon JJ, Bergstralh EJ, Jenson BM, McCarthy JT, Nath KA (2011) Outcomes of arteriovenous fistula creation after the fistula first initiative. Clin J Am Soc Nephrol 6:1996–2002. https://doi.org/10.2215/CJN.11251210

    Article  PubMed  PubMed Central  Google Scholar 

  31. Dageforde LA, Harms KA, Feurer ID, Shaffer D (2015) Increased minimum vein diameter on preoperative mapping with duplex ultrasound is associated with arteriovenous fistula maturation and secondary patency. J Vasc Surg 61:170–176. https://doi.org/10.1016/j.jvs.2014.06.092

    Article  PubMed  Google Scholar 

  32. Fokou M, Teyang A, Ashuntantang G, Kaze F, Eyenga VC, Chichom Mefire A, Angwafo F III (2012) Complications of arteriovenous fistula for hemodialysis: an 8-year study. Ann Vasc Surg 26:680–684. https://doi.org/10.1016/j.avsg.2011.09.014

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andrew S. Kucey.

Ethics declarations

The Clinical Research Ethics Committee at University College Cork approved the methods of the current study.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kucey, A.S., Joyce, D.P., O’Neill, T. et al. Patients referred for arteriovenous fistula construction: a retrospective outcome analysis. Ir J Med Sci 189, 685–691 (2020). https://doi.org/10.1007/s11845-019-02090-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11845-019-02090-9

Keywords

Navigation