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First case report of a curative wedge resection in epithelial–myoepithelial carcinoma of the lung

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Abstract

Epithelial–myoepithelial carcinoma is a well differentiated malignant neoplasm, which originates from the salivary glands. The primary pulmonary manifestation is rare—about 30 cases have been reported worldwide. In the literature, anatomical resection has been described as the standard surgical approach. In the presented case, a wedge resection was performed, with no evidence for tumor relapse in the follow-up reevaluation after 24 months. This is the first case report of a primary pulmonary epithelial–myoepithelial carcinoma that has been treated with a non-anatomical wedge resection and lymph node dissection as a curative approach.

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Abbreviations

CK-7:

Cytokeratin 7

H&E:

Hematoxylin and eosin

Ki67:

Ki-67 protein, name is derived from the city of origin (Kiel, Germany)

p63:

Tumor protein p63

PCR:

Polymerase chain reaction

S-100:

S-100-protein

SMA:

Alpha-smooth muscle actin

TTF-1:

Thyroid transcription factor-1

References

  1. Donath K, Seifert G, Schmitz R. Diagnosis and ultrastructure of the tubular carcinoma of salivary gland ducts. Epithelial–myoepithelial carcinoma of the intercalated ducts. Virchows Arch A Pathol Pathol Anat. 1972;356(1):16–31.

    Article  CAS  PubMed  Google Scholar 

  2. Arif F, Wu S, Andaz S, Fox S. Primary epithelial myoepithelial carcinoma of lung, reporting of a rare entity, its molecular histogenesis and review of the literature. Case Rep Pathol. 2012;2012:319434.

    PubMed  PubMed Central  Google Scholar 

  3. Cho SH, Park SD, Ko TY, Lee HY, Kim JI. Primary epithelial myoepithelial lung carcinoma. Korean J Thorac Cardiovasc Surg. 2014;47(1):59–62.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Nguyen CV, Suster S, Moran CA. Pulmonary epithelial–myoepithelial carcinoma: a clinicopathologic and immunohistochemical study of 5 cases. Hum Pathol. 2009;40(3):366–73.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

Data material from computed tomography with permission of Radprax Institute Solingen.

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Author notes

  1. Lars Hagmeyer and L. Tharun contributed equally to the work.

Authors and Affiliations

  1. Clinic for Pneumology and Allergology, Center for Sleep Medicine and Respiratory Care, Hospital Bethanien Solingen, Aufderhöher Straße 169-175, 42699, Solingen, Germany

    Lars Hagmeyer & W. Randerath

  2. Institute for Pathology, University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany

    L. Tharun, S. C. Schäfer & R. Büttner

  3. Clinic for Cardiac and Thoracic Surgery, University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany

    K. Hekmat

Authors
  1. Lars Hagmeyer
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  2. L. Tharun
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  3. S. C. Schäfer
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  4. K. Hekmat
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  5. R. Büttner
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  6. W. Randerath
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Corresponding author

Correspondence to Lars Hagmeyer.

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Conflict of interest

The authors declare, that there is no conflict of interest according to the guidelines of the International Committee of Medical Journal Editors.

Joint first authorship

Lars Hagmeyer (Solingen, Germany) and Lars Tharun (Cologne, Germany) contributed equally to the work. The patient was admitted to the Hospital in Solingen for the diagnosis of suspected lung cancer. All the preoperative clinical diagnostic procedures and the postoperative follow-up visits were performed in Solingen under the guidance of Lars Hagmeyer. The pathological analysis of the resected tumor was performed at the pathological Institute in Cologne by Lars Tharun. Both authors, Lars Hagmeyer and Lars Tharun, contributed equally to the analysis and interpretation of the data as well as to the writing of the manuscript.

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Hagmeyer, L., Tharun, L., Schäfer, S.C. et al. First case report of a curative wedge resection in epithelial–myoepithelial carcinoma of the lung. Gen Thorac Cardiovasc Surg 65, 535–538 (2017). https://doi.org/10.1007/s11748-017-0796-7

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  • DOI: https://doi.org/10.1007/s11748-017-0796-7

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