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Impact on Dyslipidemia After Laparoscopic Sleeve Gastrectomy

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Abstract

Background

Improvement of dyslipidemia is an important benefit of bariatric surgery. The benefits of laparoscopic sleeve gastrectomy (LSG) among dyslipidemia are still a matter of debate.

Methods

We conducted a retrospective descriptive study between 2010 and 2013. Obese patients undergoing LSG, with recorded dyslipidemia at admission and a follow-up for at least 1 year, were included for analysis. Demographic characteristics, medication in use, and a complete lipid profile were collected before surgery. After surgery, weight was controlled at 1, 3, 6, and 12 months. Lipid profile was re-evaluated 1 year after surgery. Patients were divided according to weight loss into two groups: (A) adequate weight loss and (B) inadequate weight loss. Lipid profile evolution was then compared between groups.

Results

One hundred seven patients met the inclusion criteria. Pre-op mean BMI was 45.13 ± 7.5 kg/m2. One year after LSG, mean BMI was 30.6 ± 7.1 kg/m2 with a change in BMI of 11.5 ± 6.6 kg/m2, a %TWL of 26.9 ± 13.5%, and a %EWL of 60.3 ± 36.6%. Hypercholesterolemia and hypertriglyceridemia remission was achieved in 45 and 86% of the patients and improved in another 19 and 4% respectively. Seventy-four percent improved HDL levels. LDL levels improved in 39% and remitted in 37%. Medication was discontinued in 43.7%. HDL increase and LDL, TG, and non-HDL-C decrease were significantly greater in group A.

Conclusions

LSG produces an improvement in lipid profile, with a significant increase in HDL and a decrease in LDL, triglycerides, and non-HDL-C.

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Authors and Affiliations

  1. General Surgery Department, Bariatric Surgery Program, Hospital Privado Universitario de Córdoba, Naciones Unidas 346, 5016, Córdoba, Argentina

    Agustina Vigilante, Franco Signorini, Marcos Marani, Virginia Paganini, Germán Viscido, Luciano Navarro, Lucio Obeide & Federico Moser

Authors
  1. Agustina Vigilante
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  2. Franco Signorini
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  3. Marcos Marani
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  4. Virginia Paganini
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  5. Germán Viscido
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  6. Luciano Navarro
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  7. Lucio Obeide
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  8. Federico Moser
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Correspondence to Franco Signorini.

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The authors declare that they have no competing interests.

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Vigilante, A., Signorini, F., Marani, M. et al. Impact on Dyslipidemia After Laparoscopic Sleeve Gastrectomy. OBES SURG 28, 3111–3115 (2018). https://doi.org/10.1007/s11695-018-3343-4

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  • DOI: https://doi.org/10.1007/s11695-018-3343-4

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