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Displacement of the Intragastric Balloon from the Fundus to the Antrum Results in Enhanced Weight Loss

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Abstract

Background

The BioEnterics Intragastric Balloon [BIB] is a reliable, non-invasive technique to manage obesity for subjects who refuse or are unsuitable for bariatric surgery. In a prior study, BIB placed in the antrum [A] was found to have significantly better results on weight loss in relation to that in fundus [F], but many balloons initially placed in the F were eventually found in the A. The aim of the present analysis was to evaluate whether the balloon position [firmly in F, firmly in A, or transient from F to A [FA]] influences the 3- and 6-month weight loss.

Material

Six hundred sixty-eight patients that underwent successful BIB treatment were assigned into three groups: group F [n = 354], group A [n = 159], and group AF [n = 155]. Weight loss parameters were recorded and analyzed at 3 and 6 months.

Results

In all three groups, there was a significant, progressive reduction of BMI at 3 and 6 months. At 6 months, BMI reduction between groups F and A, and F and FA [p = 0.001] and groups A and FA [p = 0.018] was prominent.

Conclusion

The position of the BIB affects its effectiveness: better results when antrum is involved. This observation seems to give a great perspective to newly established gastric space-occupying devices, which aim to have a compartment constantly present in the antrum. However, further studies have to be performed in order to validate the results and more importantly to clarify the mechanisms implied.

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Authors and Affiliations

  1. Department of Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece

    Theodosios S Papavramidis, George Stavrou, Pyrros Papakostas, Vasilis Grosomanidis, Smaro Kokkota, Antonios Michalopoulos, George Kolios & Katerina Kotzampassi

Authors
  1. Theodosios S Papavramidis
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  2. George Stavrou
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  3. Pyrros Papakostas
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  4. Vasilis Grosomanidis
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  5. Smaro Kokkota
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  6. Antonios Michalopoulos
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  7. George Kolios
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  8. Katerina Kotzampassi
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Corresponding author

Correspondence to Katerina Kotzampassi.

Ethics declarations

The study was approved by the Ethics Committee of our University Hospital.

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from all individual participants included in the study, as it also stated in the text.

Ethical Approval

For this type of study, formal consent is not required.

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Papavramidis, T.S., Stavrou, G., Papakostas, P. et al. Displacement of the Intragastric Balloon from the Fundus to the Antrum Results in Enhanced Weight Loss. OBES SURG 28, 2374–2378 (2018). https://doi.org/10.1007/s11695-018-3168-1

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  • DOI: https://doi.org/10.1007/s11695-018-3168-1

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