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High Vitamin D Deficiency Rate in Metabolic Inpatients: Is Bariatric Surgery Planning Found Guilty?

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Abstract

Background

High rates of vitamin D insufficiency are usually found in obese patients, even before any malabsorptive bariatric surgery. It is not clear whether they lack vitamin D because of different food intake, different solar exposure, or different storage pathways or bioavailability in adipose tissue. To better understand vitamin D deficiency, we studied different categories of inpatients.

Methods

We collected clinical and biological data from 457 consecutive inpatients during a year: 217 nonobese diabetic patients, 159 obese nonsurgical diabetic patients, 46 obese surgical nondiabetic patients, and 35 obese surgical diabetic patients. Statistically significant differences between two mean 25-hydroxyvitamin D (25(OH)D) levels were defined at the 5 % level using a Z-test.

Results

Vitamin D deficiency was found in 69 % of the patients, while 24 % had a normal level and 7 % an optimal level. A significant difference was found between obese (25(OH)D = 40.3 nmol/l) and nonobese patients (25(OH)D = 46.8 nmol/l). Patients undergoing bariatric surgery were not different from the other obese patients.

Conclusion

No significant difference in 25(OH) vitamin D level could be demonstrated between obese patients before bariatric surgery and obese patients with no obesity surgery project. No difference was found between our Parisian obese population and a Spanish obese population, which benefits from a better solar exposure. Both findings suggest that obesity itself is the link with vitamin D deficiency, independently from behavioral differences.

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Acknowledgements

This research did not receive any specific grant from any funding agency in the public, commercial, or not-for-profit sector.

Conflict of Interest

All the authors declare that there is no actual or potential conflict of interest including any financial, personal, or other relationships with other people or organizations that could inappropriately influence, or be perceived to influence, their work.

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Authors and Affiliations

  1. Department of Diabetes-Endocrinology-Nutrition, Georges Pompidou European Hospital, 20 rue Leblanc, 75015, Paris, France

    Roxane Ducloux, Cécile Janin, Hervé Ducloux & Jean-Jacques Altman

  2. Paris V—Descartes University, Paris, France

    Roxane Ducloux, Cécile Janin, Hervé Ducloux & Jean-Jacques Altman

Authors
  1. Roxane Ducloux
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  2. Cécile Janin
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Correspondence to Roxane Ducloux.

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Ducloux, R., Janin, C., Ducloux, H. et al. High Vitamin D Deficiency Rate in Metabolic Inpatients: Is Bariatric Surgery Planning Found Guilty?. OBES SURG 24, 1947–1953 (2014). https://doi.org/10.1007/s11695-014-1274-2

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  • DOI: https://doi.org/10.1007/s11695-014-1274-2

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