Skip to main content
SpringerLink
Log in

Primary malignant melanoma of esophagus: Report of four cases and review of the literatures

  • Case Report
  • Published:
Chinese Journal of Cancer Research

Abstract

Objective: To investigate the clinical features and prognosis of the primary malignant melanoma of esophagus, to try to find out a rational therapy and to evaluate the value of surgical resection. Methods: Retrospective study was conducted for four cases with Primary malignant melanoma of esophagus hospitalized from May 1975 to April 1999. The relevant literatures of primary malignant melanoma of esophagus in recent years were also reviewed. Results: Four patients received multimodality therapy including surgical resection. The survival time is 16 years, 53 months, 5 months and 6 months, respectively. Conclusion: Primary malignant melanoma of the esophagus has a poor prognosis. Surgical resection plays an important role and is indispensable. The patterns of combination treatment modality need further investigation. Preoperative therapy combined with surgical resection and post-operative therapy may be a better management.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Suzuki H, Nagoyo T. Primary tumor of the esophagus other than squamous cell carcinoma: histologic classification and statistics in the surgical and autopsied materials in Japan. Int Adv Surg Oncol 1980; 3: 73.

    PubMed  CAS  Google Scholar 

  2. Sabanathan S, Eng J, Pradhan GN. Primary malignant melanoma of the esophagus. Am J Gastroenterol 1989; 84: 475.

    Google Scholar 

  3. Baur EH. Ein fall von primaerem melanom des oesophagus. Arb Geb Pathol Anato Inst Tuebingen 1906; 5: 343.

    Google Scholar 

  4. Garfinkle JM, Cahan WG. Primary melanocarcinoma of the esophagus. Cancer 1952; 5: 921.

    Article  PubMed  CAS  Google Scholar 

  5. De Le Pava S, Nigogosyan G, Pickren JW, et al. Melanosis of the esophagus. Cancer 1963; 16: 48.

    Article  Google Scholar 

  6. Lam KY, Law S, Wong J. Malignant melanoma of the oesophagus: clinicopathological features, lack of p53 expression and steroid receptors and a review of the literature. Eur J Surg Oncol 1999; 25: 168.

    Article  PubMed  CAS  Google Scholar 

  7. Basque GJ, Boline JE, Holyoke JB. Malignant melanoma of the esophagus: frist reported case in a child. Am J Clin Pathol 1970; 53: 609.

    PubMed  CAS  Google Scholar 

  8. DiCostanzo DP, Urmacher C. Primary malignant melanoma of the esophagus. Am J Surg Pathol 1987; 11: 46.

    Article  PubMed  CAS  Google Scholar 

  9. Chalkiadakis G, wihlm JM, Morand G, et al. Primary malignant melanoma of the esophagus. Ann Thorac Surg 1985; 39: 472.

    Article  PubMed  CAS  Google Scholar 

  10. Syrigos KN, Konstadoulakis MM, Ricaniades N Leandros M, et al. Primary malignant melanoma of the esophagus: report of two cases and review of the literature. In vivo 1999; 13: 421.

    PubMed  CAS  Google Scholar 

  11. Yoo CC, Levine MS, McLarney JK, et al. Primary malignant melanoma of the esophagus: radiographic findings in seven patients. Radiology 1998; 209: 455.

    PubMed  CAS  Google Scholar 

  12. Joob AW, Haines GK 3rd, Kies MS, et al. Primary malignant melanomao of the esophagus. Ann Thorac Surg 1995; 60: 217.

    PubMed  CAS  Google Scholar 

  13. Naomoto Y, Perdomo JA, Kamikawa Y, et al. Primary malignant melanoma of the esophagus: report of a case successfully treated with pre- and post-operative adjuvant hormone-chemotherapy. Jpn J Clin Oncol 1998; 28: 758.

    Article  PubMed  CAS  Google Scholar 

  14. Sato T, Mukai M, Ando N, et al. Small cell carcinoma (non-oat cell type) of the esophagus concomitant with invasive squamous cell carcinoma and carcinoma in site. Cancer 1986;57: 328.

    Article  PubMed  CAS  Google Scholar 

  15. Caldwell CB, Bains MS, Burt M. Unusual malignant neoplasms of the esophagus. Oat cell carcinoma, melanoma, and sarcoma. J Thorac Cardiovasc Surg 1991; 101: 100.

    PubMed  CAS  Google Scholar 

  16. Taniyama K, Suzuki H, Sakuramachi S, et al. Amelanotic malignant melanoma of the esophagus: case report and review of the literature. Jpn J Clin Oncol 1990; 20: 286.

    PubMed  CAS  Google Scholar 

  17. Sabanathan S, Eng J, Pradhan GN. Primary malignant melanoma of the esophagus. Am J Gastroenterol 1990; 85: 901.

    Google Scholar 

  18. Hamdy FC, Smith JH, Kennedy A, et al. Long survival after excision of a primary malignant malanoma of the oesophagus. Thorax 1991; 46: 397.

    Article  PubMed  CAS  Google Scholar 

  19. Adili F, Monig SP. Surgical therapy of primary malignant melanoma of the esophagus. Ann Thorac Surg 1997; 63: 1461.

    Article  PubMed  CAS  Google Scholar 

  20. Turnbull AD, Rsoen P, Goodner JT, et al. primary malignant tumors of the esophagus other than typical epidermoid carcinoma. Ann Thorac Surg 1973; 15: 463.

    Article  PubMed  CAS  Google Scholar 

  21. MaCormack P, Nascimento A, Bains M, et al. Primary melanocarcinoma of the esophagus. Memorial Slaon-Kettering Cancer Bull 1979; 9: 162.

    Google Scholar 

  22. Uthoff K, Jähne J, Meyer HJ, et al. Chirurgische therapie des primären malignen Melanoms des Oesophagus. Chirurg 1996; 67: 86.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Thoracic Surgery, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, 100021, Beijing

    Zhang Hui, Wang Liang-jun & Zhao Jun

Authors
  1. Zhang Hui
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wang Liang-jun
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zhao Jun
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Wang Liang-jun.

Additional information

Biography: Zhang Hui(1968–), male, attending physician, master of medicine, Department of Surgical Oncology, the Fourth Hospital of Xuzhou,, majors in surgical oncology.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zhang, H., Wang, Lj. & Zhao, J. Primary malignant melanoma of esophagus: Report of four cases and review of the literatures. Chin. J. Cancer Res. 14, 149–153 (2002). https://doi.org/10.1007/s11670-002-0033-4

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11670-002-0033-4

Key words

CLC number

Search

Navigation