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Not only muscle mass but also muscle quality is associated with knee extension muscle strength in patients with hip fractures

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Abstract

Summary

Our results revealed that the decrease in isometric knee extension muscle strength on the operated and nonoperated sides in patients with hip fractures was associated with not only a decrease in skeletal muscle mass but also a decrease in muscle quality, characterized by a decreased PhA.

Purpose

This study aimed to assess the relationship between isometric knee extension muscle strength on the operated or nonoperated sides and PhA in patients with hip fractures at approximately 6 months postoperatively.

Methods

This study was a cross-sectional study. Skeletal muscle index (SMI), PhA, knee extension muscle strength on the operated and nonoperated sides, and other physical function variables were assessed at approximately 6 months postoperatively. To identify predictors of knee extension muscle strength on the operated and nonoperated sides, hierarchical multiple regression analysis was performed.

Results

A total of 90 patients with hip fractures were included (mean age, 80.1 ± 6.9 years). SMI (0.45) and PhA on the operated side (0.27) were the significant associated factors extracted for isometric knee extension muscle strength on the operated side (standardized partial regression coefficients), independent of age, sex, and body mass index (BMI). Movement control during one-leg standing on the nonoperated side (0.26), SMI (0.32), and PhA on the nonoperated side (0.40) were the significant associated factors extracted for isometric knee extension muscle strength on the nonoperated side, independent of age, sex and BMI.

Conclusions

Our results revealed that the decrease in isometric knee extension muscle strength on the operated and nonoperated sides in patients with hip fractures at approximately 6 months postoperatively was associated with not only a decrease in skeletal muscle mass but also a decrease in muscle quality, characterized by a decreased PhA.

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Acknowledgements

We would like to thank the members of the Osteoporosis Team, Department of Rehabilitation, Kure Kyosai Hospital and Saiseikai Kure Hospital, for their support in data collection.

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Authors and Affiliations

  1. Department of Rehabilitation, Faculty of Rehabilitation, Hiroshima International University, Kurose-Gakuendai 555-36, Higashi-Hiroshima, Hiroshima, Japan

    Takuya Umehara, Akinori Kaneguchi & Nobuhiro Kito

  2. Department of Rehabilitation, Kure Kyosai Hospital, Nishichuo 2-3-28, Kure, Hiroshima, Japan

    Keita Watanabe & Nobuhisa Katayama

  3. Department of Orthopaedic Surgery, Kure Kyosai Hospital, Nishichuo 2-3-28, Hiroshima, Kure, Japan

    Hidefumi Teramoto

  4. Department of Rehabilitation, Saiseikai Kure Hospital, Sanjo 2-1-13, Kure, Hiroshima, Japan

    Daisuke Kuwahara & Ryo Kaneyashiki

  5. Department of Orthopaedic Surgery, Saiseikai Kure Hospital, Sanjo 2-1-13, Hiroshima, Kure, Japan

    Toshiyuki Mizuno

  6. Department of Health Informatics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-Ku, Hiroshima, Hiroshima, Japan

    Masayuki Kakehashi

Authors
  1. Takuya Umehara
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  2. Akinori Kaneguchi
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  3. Keita Watanabe
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  4. Nobuhisa Katayama
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  5. Hidefumi Teramoto
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  6. Daisuke Kuwahara
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  7. Ryo Kaneyashiki
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  8. Toshiyuki Mizuno
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  9. Nobuhiro Kito
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  10. Masayuki Kakehashi
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Corresponding author

Correspondence to Takuya Umehara.

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Ethics approval

This study had been approved by the Kure Kyosai Hospital (approval number: 21–23) and Hiroshima International University (approval number: 21–043).

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All patients provided written informed consent.

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All patients provided written informed consent.

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Umehara, T., Kaneguchi, A., Watanabe, K. et al. Not only muscle mass but also muscle quality is associated with knee extension muscle strength in patients with hip fractures. Arch Osteoporos 18, 54 (2023). https://doi.org/10.1007/s11657-023-01251-9

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  • DOI: https://doi.org/10.1007/s11657-023-01251-9

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