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Factors associated with pain-related disorders and gait disturbance scores from the Japanese orthopedic association back pain evaluation questionnaire and Oswestry Disability Index in patients with osteoporosis

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Abstract

Summary

In the current study, multivariate analyses were performed to determine factors associated with low back pain (LBP) in patients with osteoporosis. Aging, high bone turnover, obesity, low trunk muscle mass, spinal global sagittal malalignment, and a high number of previous vertebral fractures were potential independent risk factors of pain-related disorders, gait disturbance, or ADL deficit due to LBP.

Purpose

Patients with osteoporosis often experience low back pain (LBP) even in the absence of acute fractures. This study identifies factors that may affect questionnaires about LBP.

Methods

The data of 491 patients with osteoporosis were retrospectively reviewed. Data included patient age, sex, body mass index (BMI), bone mineral density of the lumbar spine, tartrate-resistant acid phosphatase 5b level (TRACP5b), trunk muscle mass, sagittal vertical axis (SVA), previous vertebral fractures, secondary osteoporosis, controlling nutritional status score, pain-related disorders and gait disturbance scores from the Japanese Orthopedic Association Back Pain Evaluation questionnaire (JOABPEQ), and Oswestry disability index (ODI) scores for activities of daily living (ADL) deficit. Patients with scores of 100 for each subsection of the JOABPEQ, or an ODI scores < 12 were considered to not have dysfunction (dysfunction (-) group). Multivariate analyses were used to determine variables associated with dysfunction.

Results

Pain-related disorders score of JOABPEQ was associated with aging, high BMI, and high SVA. Aging, high TRACP5b, high BMI, low TM, high SVA, and more previous vertebral fractures were associated with gait disturbance score of JOABPEQ. ODI scores were associated with high BMI, low TM, high SVA, and more previous vertebral fractures.

Conclusions

Aging, high bone turnover, obesity, a low TM, spinal global sagittal malalignment, and a high number of previous VFs were potential independent risk factors of pain-related disorders or gait disturbance according to the JOABPEQ or ODI score in patients with osteoporosis.

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Availability of data and material

The datasets during and/or analyzed during the current study are available from the corresponding author on reasonable request.

Code availability

Not applicable.

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Acknowledgements

We thank Motoki Makabe, Yukie Arai, Kazue Takakura, and Ikumi Sekihara for their assistance with this study.

Funding

This investigation was supported in part by JOA-Subsidized Science Project Research 2018–2.

Author information

Authors and Affiliations

  1. Department of Orthopedic Surgery, School of Medicine, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0375, Japan

    Masayuki Miyagi, Gen Inoue, Kosuke Murata, Tomohisa Koyama, Akiyoshi Kuroda, Ayumu Kawakubo, Yuji Yokozeki, Yusuke Mimura, Kentaro Uchida & Masashi Takaso

  2. Department of Rehabilitation, Kitasato University Hospital, Sagamihara, Japan

    Yuta Nanri

  3. Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan

    Kazuhide Inage & Seiji Ohtori

  4. Department of Orthopaedic Surgery, St. Marianna University School of Medicine, Kawasaki, Japan

    Tsutomu Akazawa

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  1. Masayuki Miyagi
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Contributions

MM drafted the manuscript, participated in the design of the study, and conceived this study. KM, TK, AKu, AKa, YY, and YN participated in its design and collecting data. KI, TA, and SO revised the manuscript. KU carried out the statistical analysis. GI and MT conceived the study and participated in its design and coordination. All authors have read and approved the final manuscript.

Corresponding author

Correspondence to Masayuki Miyagi.

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Ethics approval

Ethical approval from our Institutional Review Board (IRB) was obtained for this study, and it has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. Approval code is #B17-197.

Consent to participate

Written informed consent was obtained from the patients for participation in this study.

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Written informed consent was obtained from the patients for the publication of this study.

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None.

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Miyagi, M., Inoue, G., Murata, K. et al. Factors associated with pain-related disorders and gait disturbance scores from the Japanese orthopedic association back pain evaluation questionnaire and Oswestry Disability Index in patients with osteoporosis. Arch Osteoporos 17, 1 (2022). https://doi.org/10.1007/s11657-021-01045-x

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