INTRODUCTION

Experiences of discrimination are an important type of psychosocial stressor that has adverse effects on both mental and physical health1. Systematic reviews reveal the strongest associations for harmful health effects are across a range of mental health outcomes including psychological distress, mental illness such as depression and anxiety, and suicidal ideation1, 2, with poor mental health as a consequence of discrimination seen among Black3, 4, Latino5, 6, Asian/Pacific Islander7, 8, American Indian9, Middle Eastern/Arab10, and White communities11. Factors influencing mental health impacts include coping style, sex, socioeconomic class, educational attainment, and racial/ethnic group affiliation1, 5, 12. One potential mechanism underlying the perceived discrimination-health relationship is allostatic load developed by heighted stress responses and negative emotional states from experiences of discrimination. Consequently, studies have suggested a dose-dependent relationship, with higher impacts of discrimination among older minority adults and/or cumulative reported experiences of discrimination13, 14.

Another contextual difference between racial/ethnic groups that may influence the experience of discrimination is immigration status and acculturation. Acculturation refers to the process by which immigrants acquire the language, customs, behaviors, and attitudes of the host culture consequent to contact with a host culture involving culturally dissimilar people and social influences15. There are both positive and negative theories of acculturation and how acculturation influences health. Positive theories include potential for upward social mobility, increased socioeconomic status or employment opportunities, increased social cohesion and community, increased understanding of the American healthcare system and preventive health practices, and development of an “American” identity16. Negative theories include adopting negative American behaviors such as change in diet or decreased physical activity, and increasing psychosocial stressors associated with acculturation (“acculturative stress”) such as a change in self-worth or self-image due to changing roles from native to host country, the pressure of acquiring a new language, balancing differing cultural values, and increased exposure to, and recognition of, discrimination17,18,19. However, the pathways by which discrimination and acculturation affect mental health are not clear18, including whether or not there exists a dose-dependent relationship with older adults being disproportionately impacted.

The present study therefore aims to examine the pathways by which discrimination and acculturation affect mental health. We examine (1) the relationship between self-perceived discrimination and mental illness across racial/ethnic groups, (2) whether acculturation mediates the effect of discrimination and mental illness, and (3) whether the perceived discrimination and mental illness relationship differ for different levels of acculturation and age.

METHODS

Study Sample

This study is a secondary analysis of a publicly available dataset, the 2015–2016 adult California Health Interview Survey (CHIS), which is the largest state health survey in the USA and the most recent complete 2-year cycle of the CHIS. The CHIS is a cross-sectional, population-based telephone survey administered biannually and is approved by the Institutional Review Board of the University of California, Los Angeles (UCLA). It is conducted in six languages: English, Spanish, Chinese (Mandarin and Cantonese dialects), Vietnamese, Korean, and Tagalog. Participants in the CHIS are chosen at random. The adult response rate after screening the household was 47.2% in 2015 and 44.6% in 201620. The sample includes both households with landlines and those with cell phones only. It collects information for all age groups on health status, health conditions, health-related behaviors, health insurance coverage, access to healthcare services, and other health-related issues for California’s non-institutionalized population. Our study subsample included only the 42,089 adults (ages 18–85) living in households in California who completed the 2015–2016 CHIS. A total of 274 adults were excluded from our study due to nonresponses for one of our main dependent variables (self-perceived discrimination).

Measures

The Kessler 6-item Psychological Distress Scale (K6) measured symptoms of psychological distress. The K6 measures psychological distress with six questions (e.g., “How often did you feel nervous?” “How often did you feel hopeless?”), scored on a 5-point Likert scale ranging from none of the time to all of the time21. Items are summed to obtain a total score ranging from 0 to 24 with each question scored from 0 (“none of the time”) to 4 (“all of the item”). The K6 scale is a widely used indicator of nonspecific psychological distress, highly correlated with mental illness, and allows ranking of respondents on a distress scale continuum for research purposes21. Since a score of 13 or greater on the K6 has been shown to be a strong indicator of the presence of a diagnosable mental illness with considerable disability22, we created a categorical variable (K6 ≥ 13, K6 < 13).

Self-perceived discrimination was measured using one question in the CHIS 2015–2016 dataset—“How often were you treated unfairly when getting medical care over your lifetime?” Response categories ranged from 1 for “never” to 4 for “often.” A follow-up question, asking the main reason for being treated unfairly, was used for descriptive statistics to contextualize the discrimination measure further, such as how often attributes associated with racial discrimination were cited (person’s race/skin color, ancestry/national origin, and/or English speaking ability). Multiple forms of discrimination, often overlapping among racially diverse samples, have been linked to poor mental health outcomes8, 11.

The level of acculturation was assessed using three measures: place of birth (US born vs foreign born), duration of US residency (5 years, 5–9 years, and 10 or more years), and language spoken at home (speaks English only, speaks English and another language, and speaks a non-English language only), adapted from Erinosho et al.23 The duration of US residency cutoffs is based on the fact that it typically takes a minimum of 5 years to obtain US citizenship and research shows that after 10 years, the health of foreign-born immigrants tend to become similar to the US-born. A citizenship variable was not included directly into the index since this is more of a policy measure, with immigrants acculturating whether or not they obtain citizenship. Previous studies assessing optimal ways to measure acculturation have also indicated that multiple indicators of acculturation are useful, particularly when measures involve both language and duration/length of stay measures17.

Adults were assigned a score of 0–3 based on their place of birth and duration of US residency: 0 = foreign born, resided in the USA for < 5 years; 1 = foreign born, resided in the USA for 5–9 years; 2 = foreign born, resided in the USA for ≥ 10 years; and 3 = US born. Language at home was assigned scores of 0–2: 0 = speaks a non-English language only, 1 = speaks English and another language, and 2 = speaks English only. Scores assigned were assumed to create an acculturation score ranging from 0 (least acculturated) to 5 (most acculturation). Given skew towards more-acculturated individuals in the sample, the acculturation variable was dichotomized (0 = less acculturated, acculturation index score 0–3; 1 = more acculturated, acculturation index score 4–5).

Sociodemographic Control Variables

We accounted for age (continuous), sex (male/female), education level (no high school diploma/high school graduate/some college/college and above), employment status (yes/no), insurance status (yes/no), federal poverty level (0–99% of FPL/100–199% FPL/200–299% FPL/300% FPL and above), and race/ethnicity. We used the California Department of Finance race/ethnicity classification, which tabulates Latino/Hispanic as a mutually exclusive racial/ethnic category from the non-Latino/Hispanic major race categories specified by the federal Office of Management and Budget. We decided to keep White adults in the model because experiences of discrimination affect both White individuals and Middle Eastern/Arab individuals who are classified as White by the US Census and subject to discrimination11, 24.

Statistical Analysis

Analyses began with descriptive statistics and bivariate associations between study measures. To assess the relationship between self-perceived discrimination (K6 < 13 vs K6 ≥ 13) and mental illness and acculturation across racial/ethnic groups, we used logistic regression and adjusted for covariates. We ran the same model stratified by racial/ethnic group to evaluate subgroup differences. To assess whether acculturation mediates the effect of discrimination and mental illness, we ran mediational analysis using the Karlson-Holm-Breen method25, which decomposes the total effect of a variable into direct and indirect effects for a logistic regression model. Lastly, to best communicate and quantify whether the perceived discrimination and mental illness relationship differs for different levels of acculturation, we estimated marginal effects to express how the predicted probability of the outcome changes as acculturation level changes and across different age categories26. Survey-supplied weights were used to produce population estimates27. All analyses were conducted by using Stata version 15.0 (StataCorp LP, College Station, TX).

RESULTS

Table 1 displays characteristics of the study sample, stratified by race/ethnicity. Whites were significantly older than the other racial/ethnic subgroups (p value < 0.001, weighted sample mean 44.00, SE 0.032). White and Asian subgroups were the most college educated, with the Hispanic population having the highest percentage of individuals without a high school diploma. The sample was predominantly insured (> 85% across all groups), with Whites most likely to be insured and the largest difference with the Hispanic population. Similarly, there was significant stratification by poverty and race, with White income levels highest and the largest difference seen with the Hispanic population. White and Black populations had no significant difference in acculturation index scores (mostly acculturated, with > 85% US born and speaking English only at home) when compared with Hispanic, Asian, and other racial/ethnic populations. The largest acculturation gap was noted between Whites and Hispanics.

Table 1 Population Characteristics of California Adults

Among the total sample, 30.33% reported discrimination. Average reports of discrimination varied by race/ethnicity, with reports of discrimination lowest in the Asian group and highest in the Black and other racial/ethnic subgroups (p < 0.001, respectively). Attributes associated with racial/ethnic discrimination (person’s race/skin color, ancestry/national origin, and/or English speaking ability) made up the plurality of responses at 30% of the domains for self-perceived discrimination. Among Whites, dissatisfaction with the healthcare system, gender/sex, and age were the three most common reasons cited for being discriminated against in the healthcare context.

In terms of psychological distress, the sample reported, on average, low K6 scale scores with a weighted mean K6 scale score of 4.44 (SE = 0.056). Weighted mean scores were lower for Asians (4.08, SE = 0.19; p value < 0.0001).

Table 2 shows both the adjusted and unadjusted models. Supplementary Tables 3, 4, 5, 6, 7, and 8 show our sensitivity analyses examining our model with the three measures of the acculturation index independently, and across racial/ethnic groups. In the unadjusted and adjusted logistic regression models, increased discrimination and acculturation were independently associated with increased odds of mental illness (K6 ≤ 13) (p < 0.001 and p = 0.001 in adjusted model, respectively). Increased exposure to discrimination illustrates a gradient in the discrimination-mental illness association, such that those who reported higher frequencies of discrimination conferred increased odds of having mental illness. For example, reporting being treated unfairly “rarely” conferred a 1.91 increased odds of having mental illness whereas reporting unfair treatment “often” conferred a 3.85 increased odds of having mental illness, relative to those “never” reporting unfair treatment in the healthcare context (Table 2). Higher acculturation led to a 1.72 increased odds in mental illness relative to those with less acculturation (p value = 0.001). The same relationship was observed when stratified across each racial/ethnic group. A goodness of fit test indicated that our model with its set of covariates fits the data well (Prob >F = 0.71). There was no interaction between acculturation and racial/ethnic group or between discrimination and racial/ethnic group (data not shown). Mediational analysis did not show evidence of acculturation mediating self-perceived discrimination’s effect on mental illness (Fig. 1).

Table 2 The Association of Discrimination and Acculturation on Mental Illness (K6 ≥ 13) Among California Adults
Figure 1
figure 1

Mediational analysis of effect of self-perceived discrimination and mental illness, California adults. Source: California Health Interview Survey 2015–2016.Adjusted for age, sex, race/ethnicity, education, employment, poverty level, and insurance status

Different levels of acculturation led to significant change in rates of mental illness among those reporting self-perceived discrimination (Fig. 2). For example, among those reporting discrimination exposure “sometimes,” higher acculturation predicted a 19.5% rate of mental illness relative to 9.5% for those less acculturated (p value < 0.0001). Among those reporting discrimination exposure “frequently,” higher acculturation predicted a 20.0% rate of mental illness relative to 17.2% for those less acculturated (p value < 0.0001). Across four different age categories (age 18–39, 40–54, 55–69, and 70–85), there was a higher probability of mental illness in younger age groups than in older age groups, including among those with higher acculturation (Fig. 2). That is, among those reporting discrimination exposure “sometimes,” being less acculturated and in the 18–39 age category conferred a risk of mental illness at 13% relative to those who were more acculturated and in the same age category who had a predicted risk of mental illness of 26.5% (p value < 0.0001). Conversely, among those reporting the same discrimination exposure (“sometimes”) but in the 70–85 age category, the predicted risk of mental illness for those who were less acculturated was 4.6% and, for those who were more acculturated, was 10.6% (p value < 0.0001).

Figure 2
figure 2

Predicted risk of mental illness across age and acculturation levels. Source: California Health Interview Survey 2015––2016.

DISCUSSION

Our analysis yielded three major findings: (1) more frequent self-perceived discrimination was associated with increased odds of mental illness, across racial/ethnic groups; (2) acculturation did not mediate the effect of discrimination and mental illness; and (3) the perceived discrimination and mental illness relationship was more profound among those with higher acculturation and younger age.

Our results bolster previous studies supporting the relationship between discrimination and mental health1, 2, including that increased exposure to discrimination results in poorer mental health outcomes. This study adds to the literature by including analysis of multiple ethnic minority groups, including White and other racial/ethnic subgroups often excluded due to a focus on sizeable minority communities in the USA. This focus comes at the expense of Middle Eastern populations, categorized as White in the US Census, who experience discrimination and consequent negative mental health outcomes10, as well as mixed-race individuals also experiencing discrimination28. Both racial/ethnic and non-racial/ethnic discrimination can be associated with worse mental health14. Further, even White individuals themselves experience discrimination and can have poor mental health as a result—these discriminatory experiences can relate to other aspects of one’s identity such as income, weight, or gender. Future studies elucidating the differential impact of different domains of discrimination experience, beyond racial/ethnic discrimination, would be informative.

The findings of this study build upon research that has examined the relationship of discrimination to negative mental health outcomes as influenced by acculturation. Specifically, we did not observe a mediating relationship between acculturation and discrimination’s impact on mental illness, rather suggesting that higher levels of acculturation play a deleterious effect on discrimination’s impact on mental health. This complements some prior studies showing that more-acculturated Mexican immigrants reported higher rates of discrimination that less-acculturated immigrants29. Reasons for this include increased assimilation in US society resulting in increased perception of American racial dynamics, alongside emergence of a racial identity and increased perception of different or unfair treatment. In one study focusing on Latino and Black individuals, the association of healthcare discrimination with poorer mental health was weaker for recent immigrants6. The authors suggested that new immigrants might be able to protect against the mental health effects of discrimination by perceiving their negative experiences as stemming from unfamiliarity with US culture rather than their race/ethnicity or other personal identity factors.

Increased acculturation may also lead to more intermingling with individuals from other racial/ethnic groups, and thus increased exposure to interactions that may be discriminatory, or development of a racial identity better attuned to complex racial dynamics in the US16. In fact, these increased exposures may come even as someone gains social mobility on the one hand, via improved English proficiency, educational attainment, and/or employment opportunities; on the other hand, increasing social contacts may increase the odds of encountering discrimination and subsequent negative health consequences.

Increased social mobility may also lead to comparisons with reference groups (i.e., individuals with similar level of English proficiency and/or higher levels of education either in their home countries or in the US), called the relative deprivation theory30. Other studies point to shifting and eroding family bonds with greater time in the US, diminishing the protective effect of familial social networks31. There have also been studies revealing acculturative stress associated with maintaining dual or multiple identities and/or languages32.

The relationship between acculturation and discrimination’s impact on mental health may also not be unidirectional. That is, perceived discrimination may influence one’s level of acculturative stress just as acculturative stress heightens impact of discrimination on mental health. We understand these as overlapping but distinct etiologies with impacts on mental health, which further studies can continue to clarify.

Lastly, our study found that the negative impact of higher acculturation on the mental health consequences of discrimination is concentrated among younger adults rather than older adults, which suggests that this is not just an exposure issue as identified in previous studies14. This penalty on younger adults may be explained by different coping skills between younger and older adults33, differences in social networks between those age groups34, and the experience of discrimination being more proximal or salient for younger adults, thereby increasing its impact on their mental health. There is also some evidence to suggest that younger, more-acculturated individuals could experience higher psychological distress in family situations where there is an acculturation gap or acculturation dissonance between the parent (less acculturated) and the young adult child (more acculturated)35.

There are limitations to our study. First, causal conclusions cannot be determined given the cross-sectional design that does not examine temporal effects. Second, we do not explore within-group heterogeneity, which may influence experiences of discrimination and acculturation, such as among different Hispanic or Asian groups8. Third, our proxy measure for acculturation assumes a linear process, when the process of acculturation is more complex and multidimensional. For example, segmented assimilation posits a path of acculturation characterized by rapid economic and educational advancement while intentionally maintaining ethnic values16. Biculturalism suggests that individuals can be oriented toward both their cultures of origin and host culture simultaneously17. These individuals who have high levels of orientation to both mainstream US and traditional cultures may experience decreased acculturative stress and healthier outcomes because of their fluency in both cultures18. A more comprehensive evaluation of social networks and/or cultural values may outline specific cultural features that are associated with mental health, and how mainstream versus original culture orientation differently impacts perceived discrimination. Fourth, using a self-reported, single-item discrimination measure may introduce response and measurement biases, not completely capturing the full range of discrimination experiences36, 37. Further, severe events are better recalled than less severe ones, so a single-item measure may not accurately capture the effect of everyday discriminatory incidents that may have a differential impact on mental health than major lifetime discrimination37. This is not even considering multiple levels of discrimination that operate simultaneously, such as institutional discrimination that should be acknowledged alongside our study focus on self-reported, individual-level discrimination8.

With these caveats in mind, our findings from a large, representative dataset have important public health implications. The current findings suggest that the mental health needs of immigrants who may seem more integrated into US society should not be overlooked and that individuals need not have a long, lifetime experience to discrimination for it to negatively impact their mental health.