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The New Frontier: the Intestinal Microbiome and Surgery

  • Review Article
  • Published:
Journal of Gastrointestinal Surgery Aims and scope

Abstract

The microbiome exerts a remarkable effect on human physiology. The study of the human-microbiome relationship is a burgeoning field with great potential to improve our understanding of health and disease. In this review, we address common surgical problems influenced by the human microbiome and explore what is thus far known about this relationship. These include inflammatory bowel disease, colorectal neoplasms, and diverticular disease. We will also discuss the effect of the microbiome on surgical complications, specifically anastomotic leak. We hope that further research in this field will enlighten our management of these and other surgical problems.

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Authors and Affiliations

  1. Department of Surgery, University of Chicago Medicine, 5841 S. Maryland Avenue, MC 5095, Chicago, IL, 60637, USA

    Kinga B. Skowron, Benjamin D. Shogan & Neil H. Hyman

  2. Department of Medicine, Section of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, Chicago, IL, USA

    David T. Rubin

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  1. Kinga B. Skowron
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  2. Benjamin D. Shogan
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  3. David T. Rubin
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  4. Neil H. Hyman
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Correspondence to Benjamin D. Shogan.

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Skowron, K.B., Shogan, B.D., Rubin, D.T. et al. The New Frontier: the Intestinal Microbiome and Surgery. J Gastrointest Surg 22, 1277–1285 (2018). https://doi.org/10.1007/s11605-018-3744-7

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