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Prevalence of extracardiac findings in patients undergoing coronary computed tomography and additional low-dose whole-body computed tomography

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Abstract

Purpose

In patients with suspected coronary artery disease (CAD), coexisting extracardiac abnormalities have a major impact on the patient management. This study aimed to evaluate the image quality of whole-body computed tomography (CT) immediately after the coronary computed tomography angiography (CTA) and investigate the incidence of extracardiac findings in patients with suspected CAD.

Materials and methods

We enrolled 450 patients undergoing whole-body CT at 100 kVp and model-based iterative reconstruction immediately after the coronary CTA (Group A) and retrospectively reviewed 144 control patients who underwent conventional contrast-enhanced CT (120 kVp) with filtered back projection (Group B). We compared the signal-to-noise ratio (SNR) of the aorta and liver and radiation dose between the two groups. Then, we evaluated the prevalence of extracardiac findings in Group A.

Results

Compared with Group B, Group A demonstrated significantly higher aorta and liver SNR and lower radiation dose. In Group A, whole-body CT revealed 229 coexisting lesions in 165 patients, including 32 and 106 cases of oncologic and vascular diseases, respectively.

Conclusion

Additional whole-body CT after coronary CTA may provide adequate image quality. Using additional whole-body CT, 36% of patients with suspected CAD had clinically relevant coexisting findings, including malignancy.

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Funding

This research received no grant from any funding agency in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Department of Radiology, Amakusa Medical Center, Jikiba, Kameba, Amakusa city, Kumamoto, 863-0046, Japan

    Morikatsu Yoshida

  2. Department of Radiology, Yokohama City University School of Medicine, Yokohama, Japan

    Daisuke Utsunomiya

  3. Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

    Taihei Inoue & Takeshi Nakaura

  4. Department of Cardiovascular Medicine, Amakusa Medical Center, Kumamoto, Japan

    Naritsugu Sakaino

  5. Department of Surgery, Amakusa Medical Center, Kumamoto, Japan

    Kazunori Harada

  6. Department of Cardiovascular Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

    Daisuke Sueta & Kenichi Tsujita

  7. Tamana Central Hospital, Tamana, Japan

    Yasuyuki Yamashita

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  1. Morikatsu Yoshida
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  2. Daisuke Utsunomiya
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  3. Taihei Inoue
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Correspondence to Morikatsu Yoshida.

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Cite this article

Yoshida, M., Utsunomiya, D., Inoue, T. et al. Prevalence of extracardiac findings in patients undergoing coronary computed tomography and additional low-dose whole-body computed tomography. Jpn J Radiol 38, 144–153 (2020). https://doi.org/10.1007/s11604-019-00906-3

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  • DOI: https://doi.org/10.1007/s11604-019-00906-3

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