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Cinematic rendering: a new imaging approach for ulcerative colitis

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

Cinematic rendering (CR) is a new technique for visualizing volumetric three-dimensional data. The purpose of this study was to investigate the added value of CR to conventional computed tomography (CT) in the diagnosis and evaluation of ulcerative colitis (UC).

Materials and methods

We retrospectively evaluated the CT data of 48 patients (33 men, 15 women; mean age, 44.35 years) with a definitive diagnosis of UC. All patients underwent conventional CT and CR, and had colonoscopy results. Two radiologists independently reviewed the conventional CT images first without and then with CR. Then, the imaging value of CR was evaluated by both radiologists together. The readers were blinded to the disease extent. The diagnostic performance of CR for both readers was assessed by receiver-operating characteristic (ROC) curve analysis.

Results

There were 23 cases of mild to moderate UC and 25 cases of severe UC, which were divided into two groups. Both readers showed improved diagnostic performance with the addition of CR (the area under the ROC curve improved from 0.676 to 0.804, P = 0.0255, and from 0.679 to 0.826, P = 0.0049, for readers 1 and 2, respectively). Full view of the lesion and contrast enhancement was not significantly different between the two groups (P > 0.05). Increased mesenteric vascularity and the comb sign on CR were more clearly observed in the severe group (P < 0.05).

Conclusion

Adding CR to conventional CT improved the diagnostic performance of evaluating the extent of UC.

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Acknowledgements

The authors would like to thank Dianke Du for his help in the process of CR construction.

Funding

This study was supported by the National Natural Science Foundation of China (Grant No. 81703155 and 81460264), the Yunnan Applied Basic Research Projects-KMU Joint Special Project (Grant No. 2017FE468 (-071)) and Yunnan Health Training Project of High Level Talents (H-2017005).

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Authors and Affiliations

  1. Department of Radiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, No. 519 Kunzhou Road, Xishan District, Kunming, 650118, Yunnan, People’s Republic of China

    Jun Yang, Chengde Liao & Qinqing Li

  2. Department of Medical Imaging, The First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Road, Kunming, 650032, Yunnan, People’s Republic of China

    Jun Yang, Xu Liu & Dan Han

Authors
  1. Jun Yang
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  2. Xu Liu
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  3. Chengde Liao
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  4. Qinqing Li
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  5. Dan Han
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Corresponding authors

Correspondence to Qinqing Li or Dan Han.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This research carried out in accordance with the ethical standards our institutional committee. This was a retrospective, single-center study approved by our institutional review board, and the requirement for informed written consent was waived.

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Yang, J., Liu, X., Liao, C. et al. Cinematic rendering: a new imaging approach for ulcerative colitis. Jpn J Radiol 37, 590–596 (2019). https://doi.org/10.1007/s11604-019-00844-0

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  • DOI: https://doi.org/10.1007/s11604-019-00844-0

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