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A novel utility of 99mTc-GSA SPECT/CT fusion imaging: detection of inadequate portal vein embolization

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Abstract

Purpose

Our aim was to determine the utility of Tc-99m-diethylenetriaminepentaacetic acid-galactosyl human serum albumin single-photon-emission computed tomography (99mTc-GSA SPECT/CT) fusion imaging for detecting incomplete portal vein embolization (PVE).

Materials and methods

Fifty-five candidates underwent PVE. Among them, five underwent second PVE. Detectability of first inadequate PVE using CT and 99mTc-GSA SPECT/CT fusion imaging was analyzed.

Results

Cases of inadequate PVE were detected in three patients using CT and in five using 99mTc-GSA SPECT/CT fusion imaging. Fusion imaging detected two cases of insufficient PVE in which portal branches were apparently well embolized on CT. Median value for volumetric rate in the embolized liver was 63.3% after the first PVE and 54.7% after the second (P < 0.01). Median functional rate value in embolized liver was 60.1% after the first PVE and 49.4% after the second (P < 0.01). Median value for change of volumetric and functional rates in embolized liver after the second PVE was 7.1 and 10.3%, respectively, and change of functional rate was greater than that of volumetric rate (P < 0.01).

Conclusions

99mTc-GSA SPECT/CT fusion imaging was useful for detecting inadequate PVE, and second PVE was effective for increasing volumetric and functional rates.

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Kochi Health Sciences Center, 2125 Ike, Kochi, Japan

    Tatsuaki Sumiyoshi, Yasuo Shima, Takehiro Okabayashi, Yuichi Saisaka & Kenta Sui

  2. Department of Radiology, Kochi Health Sciences Center, Kochi, Japan

    Yasuhiro Hata, Yoshihiro Noda, Michihiko Kouno & Sojiro Morita

  3. Department of Medical Oncology, Kochi Health Sciences Center, Kochi, Japan

    Yuji Negoro

  4. Department of Surgery, Applied Life Sciences Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

    Taijiro Sueda

Authors
  1. Tatsuaki Sumiyoshi
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  2. Yasuo Shima
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  3. Takehiro Okabayashi
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  4. Yasuhiro Hata
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  5. Yoshihiro Noda
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  6. Michihiko Kouno
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  7. Yuichi Saisaka
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  8. Kenta Sui
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  9. Sojiro Morita
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  10. Yuji Negoro
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  11. Taijiro Sueda
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Corresponding author

Correspondence to Tatsuaki Sumiyoshi.

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Sumiyoshi, T., Shima, Y., Okabayashi, T. et al. A novel utility of 99mTc-GSA SPECT/CT fusion imaging: detection of inadequate portal vein embolization. Jpn J Radiol 35, 748–754 (2017). https://doi.org/10.1007/s11604-017-0689-9

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  • DOI: https://doi.org/10.1007/s11604-017-0689-9

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