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A new endovascular strategy utilizing a hybrid procedure for long segmental occlusion by acute arterial thromboembolism in the lower extremity

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Abstract

Purpose

To evaluate a new endovascular strategy utilizing a hybrid procedure for long segmental arterial thromboembolism in a lower extremity by historical comparison with conventional endovascular strategy.

Materials and methods

In a new endovascular strategy, a hybrid procedure was performed for long segmental thromboembolism (longer than 15 cm) and an endovascular procedure for short segmental thromboembolism. The new strategy group (Group A) consisted of 24 procedures (13 hybrid procedures, 11 endovascular procedures) in 19 patients. Data were retrospectively collected from 24 consecutive procedures in 23 patients treated with the conventional strategy (Group B).

Result

The technical success of Groups A and B was 24/24 and 20/24, respectively (p = 0.11). Major amputation or mortality was not observed in Group A, whereas 3 major amputations and 4 deaths occurred in Group B. Clinical failure in Groups A and B was 0/24 and 7/24, respectively (p < 0.05). Continuous urokinase (UK) infusion was needed in 1/24 in Group A and 14/24 in Group B (p < 0.05). Mean procedure time was 4 h 17 min for Group A and 21 h 30 min for Group B (p < 0.05).

Conclusion

The hybrid procedure may be faster and more effective than the conventional treatment in long segmental arterial thromboembolisms, while the conventional treatment is still effective for short segmental occlusions.

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References

  1. Setacci C, De Donato G, Setacci F, Sirignano P, Galzerano G. Hybrid procedures for acute limb ischemia. J Cardiovasc Surg (Torino). 2012;53(1 Suppl 1):133–43.

    CAS  PubMed  Google Scholar 

  2. Creager MA, Kaufman JA, Conte MS. Clinical practice. Acute limb ischemia. N Engl J Med. 2012;366:2198–206.

    Article  CAS  PubMed  Google Scholar 

  3. Argyriou C, Georgakarakos E, Georgiadis GS, Antoniou GA, Schoretsanitis N, Lazarides M. Hybrid revascularization procedures in acute limb ischemia. Ann Vasc Surg. 2014;28:1456–62.

    Article  PubMed  Google Scholar 

  4. Matsagkas M, Kouvelos G, Arnaoutoglou E, Papa N, Labropoulos N, Tassiopoulos A. Hybrid procedures for patients with critical limb ischemia and severe common femoral artery atherosclerosis. Ann Vasc Surg. 2011;25:1063–9.

    Article  PubMed  Google Scholar 

  5. Sacks D, Marinelli DL, Martin LG, Spies JB, Society of Interventional Radiology Technology Assessment C. Reporting standards for clinical evaluation of new peripheral arterial revascularization devices. J Vasc Interv Radiol. 2003;14(9 Pt 2):S395–404.

  6. Patel N, Sacks D, Patel RI, Moresco KP, Ouriel K, Gray R, et al. SIR reporting standards for the treatment of acute limb ischemia with use of transluminal removal of arterial thrombus. J Vasc Interv Radiol. 2003;14(9 Pt 2):S453–65.

    Article  PubMed  Google Scholar 

  7. Argyriou C, Georgakarakos E, Georgiadis GS, Antoniou GA, Schoretsanitis N, Lazarides M. Hybrid revascularization procedures in acute limb ischemia. Ann Vasc Surg. 2014;28:1456–62.

    Article  PubMed  Google Scholar 

  8. Hynes BG, Margey RJ, Ruggiero N 2nd, Kiernan TJ, Rosenfield K, Jaff MR. Endovascular management of acute limb ischemia. Ann Vasc Surg. 2012;26:110–24.

    Article  PubMed  Google Scholar 

  9. Blaisdell FW, Steele M, Allen RE. Management of acute lower extremity arterial ischemia due to embolism and thrombosis. Surgery. 1978;84:822–34.

    CAS  PubMed  Google Scholar 

  10. Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischemia of the lower extremity. The STILE trial. Ann Surg. 1994;220:251–66 (discussion 66–8).

  11. Nilsson L, Albrechtsson U, Jonung T, Ribbe E, Thorvinger B, Thorne J, et al. Surgical treatment versus thrombolysis in acute arterial occlusion: a randomised controlled study. Eur J Vasc Surg. 1992;6:189–93.

    Article  CAS  PubMed  Google Scholar 

  12. Ouriel K, Shortell CK, DeWeese JA, Green RM, Francis CW, Azodo MV, et al. A comparison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia. J Vasc Surg. 1994;19:1021–30.

    Article  CAS  PubMed  Google Scholar 

  13. Ouriel K, Veith FJ, Sasahara AA. Thrombolysis or peripheral arterial surgery: phase I results. TOPAS Investigators. J Vasc Surg. 1996;23:64–73 (discussion 4–5).

    Article  CAS  PubMed  Google Scholar 

  14. Ouriel K, Veith FJ, Sasahara AA. A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators. N Engl J Med. 1998;338:1105–11.

  15. de Donato G, Setacci F, Sirignano P, Galzerano G, Massaroni R, Setacci C. The combination of surgical embolectomy and endovascular techniques may improve outcomes of patients with acute lower limb ischemia. J Vasc Surg. 2014;59:729–36.

    Article  PubMed  Google Scholar 

  16. Swischuk JL, Fox PF, Young K, Hussain S, Smouse B, Castaneda F, et al. Transcatheter intra-arterial infusion of rt-PA for acute lower limb ischemia: results and complications. J Vasc Interv Radiol. 2001;12:423–30.

    Article  CAS  PubMed  Google Scholar 

  17. Ouriel K, Gray B, Clair DG, Olin J. Complications associated with the use of urokinase and recombinant tissue plasminogen activator for catheter-directed peripheral arterial and venous thrombolysis. J Vasc Interv Radiol. 2000;11:295–8.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to HwanHoon Chung.

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Kwak, J., Chung, H., Lee, S. et al. A new endovascular strategy utilizing a hybrid procedure for long segmental occlusion by acute arterial thromboembolism in the lower extremity. Jpn J Radiol 34, 494–502 (2016). https://doi.org/10.1007/s11604-016-0542-6

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  • DOI: https://doi.org/10.1007/s11604-016-0542-6

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