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One-step preparation of carbon quantum dots-reduced graphene oxide nanocomposite–modified glass carbon electrode for the simultaneous detection of ascorbic acid, dopamine, and uric acid

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Abstract

In this manuscript, carbon quantum dots-reduced graphene oxide (CQDs-rGO) nanocomposite was modified on the surface of glass carbon electrode (GCE) via an one-step co-deposition method to fabricate an effective electrochemical senor for the simultaneous detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA). Due to the strong synergetic effect between CQDs and rGO, the sensor exhibited good selectivity and high catalytic activity toward AA, DA, and UA. The peak potential differences of simultaneous detection for AA-DA, DA-UA, and AA-UA were calculated as 0.147 V, 0.135 V, and 0.282 V, respectively. And the linear responses of AA, DA, and UA were found in the ranges of 0.2–0.9 mM (R2 = 0.99) and 1.4–4.2 mM (R2 = 0.99), 5–9 μM (R2 = 0.98) and 11–81 μM (R2 = 0.99), and 20–90 μM (R2 = 0.99) and 140–300 μM (R2 = 0.99), respectively. The as-prepared sensor contributed a fresh idea to the simultaneous detection of AA, DA, and UA, and has a broad prospect in practical application.

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Funding

Financial supports from the National Natural Science Foundation of China (Grant Nos. 81973944, 81503636, and 81704146) and the National S&T Major Project (No. 2018ZX09201011) are acknowledged.

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Author notes

  1. Yuyun Wei and Zhifang Xu contributed equally to this work.

Authors and Affiliations

  1. Research Center of Experimental Acupuncture Science, College of Acumox and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China

    Yuyun Wei, Zhifang Xu, Shenjun Wang, Yangyang Liu & Yuxin Fang

  2. College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, People’s Republic of China

    Di Zhang

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  1. Yuyun Wei
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Correspondence to Di Zhang or Yuxin Fang.

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Wei, Y., Xu, Z., Wang, S. et al. One-step preparation of carbon quantum dots-reduced graphene oxide nanocomposite–modified glass carbon electrode for the simultaneous detection of ascorbic acid, dopamine, and uric acid. Ionics 26, 5817–5828 (2020). https://doi.org/10.1007/s11581-020-03703-5

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