Abstract
Motor adaptation is the ability to develop new motor skills that makes performing a consolidated motor task under different psychophysical conditions possible. There exists a proven relationship between prior brain activity at rest and motor adaptation. However, the brain activity at rest is highly variable both between and within subjects. Here we hypothesize that the cortical activity during the original task to be later adapted is a more reliable and stronger determinant of motor adaptation. Consequently, we present a study to find cortical areas whose activity, both at rest and during first-person virtual reality simulation of bicycle riding, characterizes the subjects who did and did not adapt to ride a reverse steering bicycle, a complex motor adaptation task involving all limbs and balance. The results showed that cortical activity differences during the simulated task were higher, more significant, spatially larger, and spectrally wider than at rest for good performers. In this sense, the activity of the left anterior insula, left dorsolateral and ventrolateral inferior prefrontal areas, and left inferior premotor cortex (action understanding hub of the mirror neuron circuit) during simulated bicycle riding are the areas with the most descriptive power for the ability of adapting the motor task.
Trials registration Trial was registered with the NIH Clinical Trials Registry (clinicaltrials.gov), with the registration number NCT02999516 (21/12/2016).
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According to the funding institutions and informed consent, the authors do not have permission to publicly share the data taken from the subjects in the study. Data can be individually delivered upon direct request after consideration.
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We would like to express our sincere gratitude to all volunteers who were involved in the study.
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This work was supported by the Programas de Actividades I + D en la Comunidad de Madrid and cofunded by Structural Funds of the EU under grant RoboCity2030-DIH-CM Madrid Robotics Digital Innovation Hub “Robótica aplicada a la mejora de la calidad de vida de los ciudadanos. fase IV” [S2018/NMT-4331].
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JIS: Conceptualization; Data curation; Formal analysis; Software; Validation; Visualization; Roles/Writing—original draft; Writing—review & editing. DM-G: Conceptualization; Funding acquisition; Investigation; Methodology; Project administration; Resources; Supervision; Validation; Writing—original draft; Writing—review & editing. RF-P: Investigation; Methodology; Validation; Writing—original draft. VD: Investigation; Methodology; Validation; Writing—original draft. MB: Investigation; Methodology; Validation; Writing—original draft. MB: Investigation; Methodology; Validation; Writing—original draft. MDC: Conceptualization; Formal analysis; Resources; Validation; Visualization; Writing—review and editing.
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Serrano, J.I., Muñoz-García, D., Ferrer-Peña, R. et al. Prior cortical activity differences during an action observation plus motor imagery task related to motor adaptation performance of a coordinated multi-limb complex task. Cogn Neurodyn 14, 769–779 (2020). https://doi.org/10.1007/s11571-020-09633-2
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DOI: https://doi.org/10.1007/s11571-020-09633-2