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Evaluation of capillary blood volume in the lower limb muscles after exercise by intravoxel incoherent motion

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Abstract

Purpose

The purpose of this study was to evaluate the change in capillary blood volume in the muscles of the lower limbs, before and after exercise, using intravoxel incoherent motion (IVIM).

Materials and methods

Diffusion-weighted images were obtained (with 16 b values) from the thigh and leg muscles of 11 subjects. The imaging was obtained before and immediately exercise; additionally, imaging was performed at 3 h, 6 h, and 24 h after exercise, and an IVIM index was calculated. The exercise involved walking up and down a flight of stairs (140 steps) ten times. The IVIM of each time course—before and after the exercise—was compared. In addition, we examined the correlation of IVIM measurements with the degree of the muscle ache that occurred at 24 h following the exercise.

Results

The IVIM index significantly increased after exercise compared with that before exercise (P < 0.01). IVIM decreased at 3 h following exercise, but increased again at 24 h. A correlation was found between the IVIM index at 24 h after exercise and the degree of the muscle ache (r = 0.80)

Conclusions

The capillary blood volume significantly increased after exercise when compared to before exercise. The capillary blood volume decreased after exercise at 3 h and 6 h following exercise, but it increased again at 24 h. There was a correlation between the degree of muscle ache and the amount of capillary blood volume measured from the femoral muscle at 24 h after exercise.

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Funding

The authors state that this work has not received any funding.

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Authors and Affiliations

  1. Graduate School, Gunma Prefectural College of Health Sciences, 323-1, Kamioki-machi, Maebashi, Gunma, Japan

    Akio Ogura, Hana Sotome, Ayumi Asai & Atsuya Fuju

  2. Department of Radiology, Fujioka General Hospital, Fujioka, Japan

    Hana Sotome

  3. Department of Radiology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan

    Ayumi Asai

  4. Department of Radiology, Kiryu Kosei General Hospital, Kiryu, Japan

    Atsuya Fuju

Authors
  1. Akio Ogura
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  2. Hana Sotome
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Correspondence to Akio Ogura.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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The scientific guarantor of this publication is Dr. Kuniaki Takada.

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Ogura, A., Sotome, H., Asai, A. et al. Evaluation of capillary blood volume in the lower limb muscles after exercise by intravoxel incoherent motion. Radiol med 125, 474–480 (2020). https://doi.org/10.1007/s11547-020-01163-5

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  • DOI: https://doi.org/10.1007/s11547-020-01163-5

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