Abstract
Fungicides based on dithiocarbamates have been used to protect crops from fungal diseases for more than half a century. The purpose of this work was to show the potential impact of improper potato storage on the analysis of mancozeb and other dithiocarbamates. The resulting field samples were divided into two parts. The first part was subjected to sample preparation without violation of storage conditions. Sample preparation of the second part of the sample was carried out after artificially simulated storage violation conditions. The method for the analysis of dithiocarbamates is based on the acid hydrolysis of the sample with the formation of carbon disulphide and its subsequent analysis using GC-FPD. The results of the analysis showed the content in the experimental and control samples of a large amount of carbon disulphide, which is not a product of the hydrolysis of mancozeb. Thus, it is not possible to estimate the correct amount of mancozeb.
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References
1.2997—12. Determination of residual amounts of dithiocarbamates (tiram, mankoceba, metiram and tsineb) in soil and water by gas chromatographic vapor phase [WWW Document], 2015. URL https://www.rospotrebnadzor.ru/bitrix/redirect.php?event1=file&event2=download&event3=muk-4.1.2997_12.doc&goto=/upload/iblock/46b/muk-4.1.2997_12.doc. Accessed 6 Feb 2022
Abakerli RB, Sparrapan R, Sawaya ACHF, Eberlin MN, Jara JLP, Rodrigues NR, Fay EF, Luiz AJB, Galvão TDL, Martins DDS, Yamanishi OK, Toledo HHB (2015) Carbon disulfide formation in papaya under conditions of dithiocarbamate residue analysis. Food Chem 188:71–76. https://doi.org/10.1016/j.foodchem.2015.04.059
Anastassiadou M, Bernasconi G, Brancato A, Carrasco Cabrera L, Ferreira L, Greco L, Jarrah S, Kazocina A, Leuschner R, Magrans JO, Miron I, Nave S, Pedersen R, Reich H, Rojas A, Sacchi A, Santos M, Theobald A, Vagenende B, Verani A (2020) Review of the existing maximum residue levels for chlorantraniliprole according to Article 12 of Regulation (EC) No 396/2005. EFSA J 18:6235. https://doi.org/10.2903/J.EFSA.2020.6235
Barba FJ, Nikmaram N, Roohinejad S, Khelfa A, Zhu Z, Koubaa M (2016) Bioavailability of glucosinolates and their breakdown products: impact of processing. Front Nutr 3:24. https://doi.org/10.3389/FNUT.2016.00024/BIBTEX
EPA (1993) Method 630.1: the determination of dithiocarbamates pesticides in municipal and industrial wastewater [WWW Document]. URL https://www.epa.gov/sites/default/files/2015-10/documents/method_630-1_1993.pdf. Accessed 29 Feb 2022
Ermete R (2012) Clinical trials and communicating safely. Clin J Oncol Nurs 16:25–27. https://doi.org/10.1188/12.CJON.25-27
European Food Safety Authority (EFSA) (2019) The 2017 European Union report on pesticide residues in food. EFSA Journal. Eur. Food Saf. Auth. 17, e05743. https://doi.org/10.2903/j.efsa.2019.5743
Fungicides Market (Mancozeb, Chlorothalonil, Metalaxyl, Strobilurin, and Others) for Cereals & Grains, Oilseeds & Pulses, Fruits & Vegetables, and Other Crops - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2015 - 2023 [WWW Document], n.d. URL https://www.prnewswire.com/news-releases/fungicides-market-mancozeb-chlorothalonil-metalaxyl-strobilurin-and-others-for-cereals--grains-oilseeds--pulses-fruits--vegetables-and-other-crops---global-industry-analysis-size-share-growth-trends-and-forecast-20-300243678.html. Accessed 5.29.22
Galuchie L, Stewart C, Meloni F (2021) Protocol deviations: a holistic approach from defining to reporting. Ther Innov Regul Sci 55:733–742. https://doi.org/10.1007/s43441-021-00269-w
Ghooi R, Bhosale N, Wadhwani R, Divate P, Divate U (2016) Assessment and classification of protocol deviations. Perspect Clin Res 7:132. https://doi.org/10.4103/2229-3485.184817
Halimehjani AZ, Hooshmand SE, Shamiri EV (2014) Synthesis of α-phthalimido-α′-dithiocarbamato propan-2-ols via a one-pot, three-component epoxide ring-opening in water. Tetrahedron Lett 55:5454–5457. https://doi.org/10.1016/j.tetlet.2014.08.017
Holland PT, Hamilton D, Ohlin B, Skidmore M (1994) Pesticides report 31: effects of storage and processing on pesticide residues in plant products (technical report). Pure Appl Chem 66:335–356. https://doi.org/10.1351/pac199466020335
Hwang ES, Bornhorst GM, Oteiza PI, Mitchell AE (2019a) Assessing the fate and bioavailability of glucosinolates in kale (Brassica oleracea) using simulated human digestion and Caco-2 cell uptake models. J Agric Food Chem 67:9492–9500. https://doi.org/10.1021/acs.jafc.9b03329
Hwang IM, Park B, Dang YM, Kim SY, Seo HY (2019b) Simultaneous direct determination of 15 glucosinolates in eight Brassica species by UHPLC-Q-Orbitrap-MS. Food Chem 282:127–133. https://doi.org/10.1016/j.foodchem.2018.12.036
Kakitani A, Yoshioka T, Nagatomi Y, Harayama K (2017) A rapid and sensitive analysis of dithiocarbamate fungicides using modified QuEChERS method and liquid chromatography-tandem mass spectrometry. J Pestic Sci 42:145–150. https://doi.org/10.1584/JPESTICS.D17-025
Liu J, Sun Z, Zou Y, Li W, He F, Huang X, Lin C, Cai Q, Wisniewski M, Wu X (2022) Pre- and postharvest measures used to control decay and mycotoxigenic fungi in potato (Solanum tuberosum L.) during storage. Crit Rev Food Sci Nutr 62:415–428. https://doi.org/10.1080/10408398.2020.1818688
Mikhaylikova VV, Strebkova NS, Pustovalova EA (2020) Active substances – the basis of chemical plant protection. Agrochemistry 44–46. https://doi.org/10.31857/S0002188120050105
Musita CN, Okoth MW, Abong’ GO (2019) Postharvest handling practices and perception of potato safety among potato traders in Nairobi, Kenya. Int J Food Sci 2019, 2342619. https://doi.org/10.1155/2019/2342619
Németh AG, Keserű GM, Ábrányi-Balogh P (2019) A novel three-component reaction between isocyanides, alcohols or thiols and elemental sulfur: a mild, catalyst-free approach towards O -thiocarbamates and dithiocarbamates. Beilstein J Org Chem 15:1523–1533. https://doi.org/10.3762/bjoc.15.155
Nikitin A (2012) Mancozeb [WWW Document]. Newsp. Artic. Plant Prot. URL https://www.agroxxi.ru/gazeta-zaschita-rastenii/zrast/mankoceb.html. Accessed 6 May 2022
Pecháček R, Velísek J, Hrabcová H (1997) Decomposition products of allyl isothiocyanate in aqueous solutions. J Agric Food Chem 45:4584–4588. https://doi.org/10.1021/jf970316z
Perz RC, Van Lishaut H, Schwack W (2000) CS2 blinds in Brassica crops: false positive results in the dithiocarbamate residue analysis by the acid digestion method. J Agric Food Chem 48:792–796. https://doi.org/10.1021/jf9905323
Popov S, Dorozhkina LA, Kalinin VA (2003) Fundamentals of chemical plant protection. Art-Lion, Moscow
Ranu BC, Saha A, Banerjee S (2008) Catalysis by ionic liquids: significant rate acceleration with the use of [pmIm]Br in the three-component synthesis of dithiocarbamates. Eur J Org Chem 2008:519–523. https://doi.org/10.1002/ejoc.200700842
Rawani A, Ghosh A, Laskar S, Chandra G (2014) Glucosinolate from leaf of Solanum nigrum L. (Solanaceae) as a new mosquito larvicide. Parasitol Res 113:4423–4430. https://doi.org/10.1007/s00436-014-4120-5
Roy K-M (2000) Thiols and organic sulfides. In: Ullmann’s encyclopedia of industrial chemistry. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. https://doi.org/10.1002/14356007.a26_767
Safa KD, Tavakkoli Osgoei S, Alyari M (2014) Synthesis of novel dithiocarbamyl-containing organosilicon compounds. J Sulfur Chem 35:683–690. https://doi.org/10.1080/17415993.2014.953163
Salerno SM, Wrenn KD, Slovis CM (1991) Monitoring EMS protocol deviations: a useful quality assurance tool. Ann Emerg Med 20:1319–1324. https://doi.org/10.1016/s0196-0644(05)81074-1
Tausz M, Gullner G, Kömives T, Grill D (2003) The role of thiols in plant adaptation to environmental stress. In: Sulphur in plants. Springer, Netherlands, pp 221–244. https://doi.org/10.1007/978-94-017-0289-8_12
Yigit N, Velioglu YS (2020) Effects of processing and storage on pesticide residues in foods. Crit Rev Food Sci Nutr 60:3622–3641. https://doi.org/10.1080/10408398.2019.1702501
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EA: concept, technical research work, chromatographic studies, data analysis, and writing and AK: field work, sampling, chromatographic studies, data analysis, and writing. All authors read and approved the final manuscript.
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Alekseev, E., Komarova, A. Effect of Potato Storage Conditions on the Quality of Dithiocarbamate Analysis. Potato Res. (2023). https://doi.org/10.1007/s11540-023-09666-0
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DOI: https://doi.org/10.1007/s11540-023-09666-0