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Effect Modification of Illicit Drug Use on Symptoms of a Major Depressive Episode to Better Understand Binge Drinking by Adolescents and Adults in the United States

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Abstract

The association between symptoms of a major depressive episode (MDE) and binge drinking has mixed results. This study examined the association between binge drinking and symptoms of an MDE and other substance use such as illicit drug use and marijuana use. Data were extracted from the 2019 National Survey on Drug Use and Health. A weighted multivariable logistic regression analysis was used to determine the association between binge drinking and MDE symptoms. Weighted moderation analyses were performed to determine whether the effects of MDE symptoms on binge drinking varied by needing treatment for substance use disorders, other substances use, and sociodemographic factors. People who engaged in binge drinking were within ages 18–25 or 26–34, males, non-Hispanic Whites, had some college credit but no degree, and had a total family income of $75,000 or more. People who had MDE symptoms had lower odds of binge drinking, but people who needed treatment for illicit drug or alcohol use, used marijuana, and used illicit drug other than marijuana had higher odds of binge drinking. Race/ethnicity and illicit drug use other than marijuana moderated the association between MDE symptoms and binge drinking, respectively. The hypothesis that binge drinking and symptoms of an MDE and other substance use could be associated was partially supported by our findings. Future longitudinal studies could be useful to further assess whether changes in symptoms of an MDE and other substances use will lead to increases in binge drinking behavior.

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Data Availability

Publicly available at data and material at https://www.samhsa.gov/data/data-we-collect/nsduh-national-survey-drug-use-and-health.

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  1. Center for Health Promotion and Prevention Research (CHPPR), School of Public Health, The University of Texas Health Science Center at Houston (UTHealth), 7000 Fannin, Suite 2672C, Houston, TX, 77030, USA

    David Adzrago, Su-Wei Wong & Johnny Michael Wilkerson

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  1. David Adzrago
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  2. Su-Wei Wong
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  3. Johnny Michael Wilkerson
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DA served as the leading author, conceived the study, performed the statistical analyses, conducted the literature review, drafted the manuscript, and coordinated writing the manuscript. SW and JMW reviewed the previous manuscript. All authors provided critical revisions to the manuscript and approved publication of the manuscript.

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Correspondence to David Adzrago.

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Adzrago, D., Wong, SW. & Wilkerson, J.M. Effect Modification of Illicit Drug Use on Symptoms of a Major Depressive Episode to Better Understand Binge Drinking by Adolescents and Adults in the United States. Int J Ment Health Addiction 21, 2999–3016 (2023). https://doi.org/10.1007/s11469-022-00770-9

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