Abstract
Sensors for detecting glucose concentrations are crucial to medical testing. Here, we introduce silver nanoparticles (Ag NPs) uniformly distributed in space to investigate the sensing properties for detecting glucose by using the finite-different time-domain (FDTD) and experimental methods. The results show that the transmittance of dip for the proposed structural model gradually decreases as the number of Ag NPs increases, when the concentration of glucose is constant. And the transmission spectrum shows slight red shift with the increasing of the glucose concentration. Moreover, the simulation results are in agreement with the experimental results. Especially, the maximum sensitivity S = 1144.07407 nm/RIU can be realized for glucose concentration variation from 0.3 to 0.4 mol/L. The research results reveal an excellent sensing property that has important application value in medical detection.
Similar content being viewed by others
Availability of Data and Material
The data generated by the simulations and experiments during the current study are not publicly available.
Code Availability
The codes for the current study are not available.
References
Lin X, Lin W, Yang M et al (2018) Rapid colorimetric glucose detection via chain reaction amplification of acrylic functionalized Ag@SiO2 nanoparticles. RSC Adv 8(66):37729–37734
Adleman JR, Boyd DA, Goodwin DG et al (2009) Heterogenous catalysis mediated by plasmon heating. Nano Lett 9(12):4417–4423
Ma L, Liang S, Liu XL et al (2015) Synthesis of dumbbell-like gold-metal sulfide core-shell nanorods with largely enhanced transverse plasmon resonance in visible region and efficiently improved photocatalytic activity. Adv Func Mater 25(6):898–904
Alivisatos P (2004) The use of nanocrystals in biological detection. Nat Biotechnol 22(1):47–52
Nikoobakht B, El-Sayed MA (2003) Preparation and growth mechanism of gold nanorods (NRs) using seed-mediated growth method. Chem Mater 15(10):1957–1962
Hong W, Zhang Y, Gan L et al (2015) Control of plasmonic fluorescence enhancement on self-assembled 2-D colloidal crystals. J Mater Chem C 3(24):6185–6191
Homola J, Koudela I, Yee SS (1999) Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison. Sens Actuators B Chem 54(1–2):16–24
Li Z, Miao X, Cheng Z et al (2017) Hybridization chain reaction coupled with the fluorescence quenching of gold nanoparticles for sensitive cancer protein detection. Sens Actuators B Chem 243:731–737
Miao X, Cheng Z, Ma H et al (2018) Label-free platform for MicroRNA detection based on the fluorescence quenching of positively charged gold nanoparticles to silver nanoclusters. Anal Chem 90(2):1098–1103
Gao Y, Wu Y, Di J (2017) Colorimetric detection of glucose based on gold nanoparticles coupled with silver nanoparticles. Spectrochim Acta A Mol Biomol Spectrosc 173:207–212
He H, Xu X, Wu H et al (2012) Enzymatic plasmonic engineering of Ag/Au bimetallic nanoshells and their use for sensitive optical glucose sensing. Adv Mater 24(13):1736–1740
Liu A, Li M, Wang J et al (2020) Ag@Au core/shell triangular nanoplates with dual enzyme-like properties for the colorimetric sensing of glucose. Chin Chem Lett 31(5):1133–1136
Zhang X, Wei M, Lv B et al (2016) Sensitive colorimetric detection of glucose and cholesterol by using Au@Ag core–shell nanoparticles. RSC Adv 6(41):35001–35007
Chen YW, Periasamy AP, Chen CF et al (2019) Quantification of glucose via in situ growth of Cu2O/Ag nanoparticles. Sens Actuators B Chem 285:224–231
Adnan S, Kalwar NH, Abbas MW et al (2019) Enzyme-free colorimetric sensing of glucose using l-cysteine functionalized silver nanoparticles. SN Appl Sci 1(2):144
Chen Q, Fu Y, Zhang W et al (2017) Highly sensitive detection of glucose: a quantitative approach employing nanorods assembled plasmonic substrate. Talanta 165:516–521
Pan Z, Yang J, Song W et al (2021) Au@Ag nanoparticle sensor for sensitive and rapid detection of glucose. New J Chem 45(6):3059–3066
Tashkhourian J, Hormozi-Nezhad MR, Khodaveisi J et al (2011) A novel photometric glucose biosensor based on decolorizing of silver nanoparticles. Sens Actuators B Chem 158(1):185–189
Xu G, Zhu Y, Pang J (2017) Sensitive and simple detection of glucose based on single plasmonic nanorod. Anal Sci 33(2):223–227
Jang H, Min DH (2015) Highly precise plasmonic and colorimetric sensor based on enzymatic etching of nanospheres for the detection of blood and urinary glucose. RSC Adv 5(19):14330–14332
Akafzade H, Hozhabri N, Sharma SC (2021) Highly sensitive plasmonic sensor fabricated with multilayer Ag/Si3N4/Au nanostructure for the detection of glucose in glucose/water solutions. Sensors Actuators A Phys 317:112430
Cai T, Gao Y, Yan J et al (2017) Visual detection of glucose using triangular silver nanoplates and gold nanoparticles. RSC Adv 7(46):29122–29128
Heidarzadeh H (2020) Highly sensitive plasmonic biosensor based on ring shape nanoparticles for the detection of ethanol and D-glucose concentration. IEEE Trans Nanotechnol 19:397–404
Rakhshani MR, Tavousi A, Mansouri-Birjandi MA (2018) Design of a plasmonic sensor based on a square array of nanorods and two slot cavities with a high figure of merit for glucose concentration monitoring. Appl Opt 57(27):7798–7804
Hu C, Zhu Z, Zhu J (2012) Study on the relationship between density and refractive index of glucose solution by light beat method. College Phys Experiment 25(06):3–5
Funding
This work was supported by the National Natural Science Foundation of China (NSFC) (Grant No. 62065017) and the Education Department Program of Shaanxi (21JK0981).
Author information
Authors and Affiliations
Contributions
This research was planned by Zhihui He and Lingqiao Li. Numerical simulation was performed by Wei Cui, Hui He, and Lingqiao Li. Lingqiao Li did the experiments. The authors Zhihui He, Hui He, and Lingqiao Li discussed the results. Lingqiao Li wrote the original manuscript.
Corresponding author
Ethics declarations
Ethics Approval
Not applicable.
Consent to Participate
Not applicable.
Consent for Publication
Not applicable.
Competing Interests
The authors declare no competing interests.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Li, L., Cui, W., He, Z. et al. Plasmonic Sensor Based on Silver Nanoparticles for the Detection of Glucose. Plasmonics 17, 1231–1234 (2022). https://doi.org/10.1007/s11468-022-01617-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11468-022-01617-8