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Effect of resistance training on C-reactive protein, blood glucose and lipid profile in older women with differing levels of RT experience

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Abstract

The purpose of this study was to analyze the effects of a progressive resistance training (RT) program on C-reactive protein (CRP), blood glucose (GLU), and lipid profile in older women with differing levels of RT experience. Sixty-five older women (68.9 ± 6.1 years, 67.1 ± 13.1 kg) were separated according to RT experience: an advanced group composed by 35 participants who previously carried out 24 weeks of RT and a novice group composed by 30 participants without previous experience in RT (n = 30). Both groups performed a RT program comprised of eight exercises targeting all the major muscles. Training was carried out 3 days/week for 8 weeks. Serum triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), GLU, and CRP concentrations were determined pre- and post- intervention after 12 h fasting. A significant group by time interaction (P < 0.05) for the TC (novice = −1.9 % vs. advanced = 1.0 %), and CRP (novice = −22.9 % vs. advanced = −54.5 %) was observed. A main effect of time (P < 0.05) was identified for the GLU (novice = −2.6 % vs. advanced = −6.6 %), TG (novice = −12.9 % vs. advanced = −5.7 %), HDL-C (novice = +6.7 % vs. advanced = +2.6 %), and LDL-C (novice = −34.0 % vs. advanced = −25.4 %). These results suggest that RT improves the metabolic profile of older women and that training for a longer period of time seems to produce more pronounced reductions mainly on CRP.

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Authors and Affiliations

  1. Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil

    Alex S. Ribeiro, Crisieli M. Tomeleri, Mariana F. Souza, Fábio Luiz C. Pina, Matheus A. Nascimento & Edilson S. Cyrino

  2. Exercise Science Department, CUNY Lehman College, Bronx, New York, USA

    Brad J. Schoenfeld

  3. Clinical Analyses Laboratory, Londrina State University, Londrina, Brazil

    Danielle Venturini & Décio S. Barbosa

  4. Paraná State University, Paranavaí, Brazil

    Matheus A. Nascimento

  5. Rua Carmela Dutra 862, Jataizinho, PR, 86210-000, Brazil

    Alex S. Ribeiro

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  1. Alex S. Ribeiro
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  2. Crisieli M. Tomeleri
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  3. Mariana F. Souza
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  4. Fábio Luiz C. Pina
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  6. Matheus A. Nascimento
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  8. Décio S. Barbosa
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  9. Edilson S. Cyrino
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Corresponding author

Correspondence to Alex S. Ribeiro.

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Written informed consent was obtained from all participants after a detailed description of study procedures was provided. This investigation was conducted according to the Declaration of Helsinki and was approved by the local University Ethics Committee.

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Ribeiro, A.S., Tomeleri, C.M., Souza, M.F. et al. Effect of resistance training on C-reactive protein, blood glucose and lipid profile in older women with differing levels of RT experience. AGE 37, 109 (2015). https://doi.org/10.1007/s11357-015-9849-y

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