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Multiresidue method for the determination of high production volume plastic additives in river waters

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Abstract

The aim of this study was to develop a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)-based method for the multiresidue analysis of 21 plastic additives in river water. Analysed compounds included phthalates, benzophenone, bisphenol A and long- and short-chain alkylphenols (APs), which are of relevance because most of them are high production volume chemicals largely used in the plastic industry. These compounds can reach river waters due to direct discharge from wastewater treatment plants and leaching from plastic materials and microplastics present in rivers. In a first step, ionisation and acquisition parameters were optimised to obtain high sensitivity and structural information. Then, different solid-phase extraction cartridges and elution conditions were tested using Milli-Q and river water. With the optimised conditions, quality control parameters (recoveries, limits of detection, intra- and inter-day variability and blank contribution) proved that the method was accurate and selective for the trace monitoring of these compounds in river water. For nonylphenol, octylphenol and bis(2-ethylhexyl)phthalate, included in the Water Framework Directive, limits of detection were below environmental quality standard concentrations considering blank contributions. All other compounds were efficiently detected at trace levels, and focus was given to o- and p-substituted and di- and tri-substituted APs, which are first reported in the present study. A pilot survey was finally carried out to determine the occurrence of plastic additives in river waters surrounding the city of Barcelona.

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References

  • Brossa L, Marcé RM, Borrull F, Pocurull E (2005) Occurrence of twenty-six endocrine-disrupting compounds in environmental water samples from Catalonia, Spain. Environ Toxicol Chem 24:261–267

    Article  CAS  Google Scholar 

  • Capdeville MJ, Budzinski H (2011) Trace-level analysis of organic contaminants in drinking waters and groundwaters. TrAC Trends Anal Chem 30:586–606. https://doi.org/10.1016/j.trac.2010.12.006

    Article  CAS  Google Scholar 

  • Careghini A, Mastorgio AF, Saponaro S, Sezenna E (2015) Bisphenol a, nonylphenols, benzophenones, and benzotriazoles in soils, groundwater, surface water, sediments, and food: a review. Environ Sci Pollut Res 22(8):5711–5741. https://doi.org/10.1007/s11356-014-3974-5

    Article  CAS  Google Scholar 

  • Casajuana N, Lacorte S (2003) Presence and release of phthalic esters and other endocrine disrupting compounds in drinking water. Chromatographia 57:649–655. https://doi.org/10.1007/BF02491744

    Article  CAS  Google Scholar 

  • Česena M, Lenarčič K, Mislej V, Levstek M, Kovačiča A, Cimrmančič V, Uranjek N, Kosjek T, Heath D, Sollner Dolenc M, Heath E (2018) The occurrence and source identification of bisphenol compounds in wastewaters. Sci Total Environ 616–617:744–752

    Article  Google Scholar 

  • Céspedes R, Lacorte S, Ginebreda A, Barceló D (2006) Chemical monitoring and occurrence of alkylphenols, alkylphenol ethoxylates, alcohol ethoxylates, phthalates and benzothiazoles in sewage treatment plants and receiving waters along the Ter River basin (Catalonia, N. E. Spain). Anal Bioanal Chem 385(6):992–1000. https://doi.org/10.1007/s00216-006-0448-8

    Article  CAS  Google Scholar 

  • Chen D, Kannan K, Tan H, Zheng Z, Feng Y-L, Wu Y, Widelka M (2016) Bisphenol analogues other than BPA: environmental occurrence, human exposure, and toxicity—a review. Environ Sci Technol 50:5438–5453

    Article  CAS  Google Scholar 

  • Corrales J, Kristofco LA, Baylor Steele W, Yates BS, Breed CS, Spencer Williams E, Brooks BW (2015) Global assessment of bisphenol A in the environment: review and analysis of its occurrence and bioaccumulation (2015). Dose-Response:1–29. https://doi.org/10.1177/1559325815598308

  • Cortina-Puig M, Bolivar-Subirats G, Barata C, Lacorte S (2014) Transformation products of alkylphenols, in Transformation products of emerging contaminants in the environment: analysis, Processes, Occurrence, Effects and Risks. Wiley Online Books, pp. 577–612. https://doi.org/10.1002/9781118339558.ch19

  • Deblonde T, Cossu-Leguille C, Hartemann P (2011) Emerging pollutants in wastewater: a review of the literature. Int J Hyg Environ Health 214:442–448. https://doi.org/10.1016/j.ijheh.2011.08.002

    Article  CAS  Google Scholar 

  • Directive 2013/39/EU of the European Parliament and of the Council of 12 August 2013 amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy

  • ECHA (2019) Substance infocard. https://echa.europa.eu/es/substance-information/-/substanceinfo/100.001.133. Visited June 2020

  • European Commission Directive 2003/53/EC of the European Parliament and of the Council of 18 June 2003 amending for the 26th time Council Directive 76/769/EEC relating to restrictions on the marketing and use of certain dangerous substances and preparations (nonylphenol, nonylphenol ethoxylate and cement), Official Journal of the European Union L178/24 (2003), pp. 0024–0027

  • Fromme H, Kuchler T, Otto Pilz K, Muller J, Wenzel A (2002) Occurrence of phthalates and bisphenol A and F in the environment. Water Res 36(6):1429–1438. https://doi.org/10.1016/S0043-1354(01)00367-0

    Article  CAS  Google Scholar 

  • Gallart-Ayala H, Moyano E, Galceran MT (2010) Recent advances in mass spectrometry analysis of phenolic endocrine disruptors and related compounds. Mass Spectrom Rev 29:776–805. https://doi.org/10.1002/mas.20234

    Article  CAS  Google Scholar 

  • Gallart-Ayala H, Nuñez O, Moyano E, Galceran MT, Martins CPB (2011) Preventing false negatives with high-resolution mass spectrometry: the benzophenone case. Rapid Commun Mass Spectrom 25(20):3161–3166. https://doi.org/10.1002/rcm.5200

    Article  CAS  Google Scholar 

  • Guart A, Wagner M, Mezquida A, Lacorte S, Oehlmann J, Borrell A (2013) Migration of plasticisers from Tritan™ and polycarbonate bottles and toxicological evaluation. Food Chem 141:373–380. https://doi.org/10.1016/j.foodchem.2013.02.129

    Article  CAS  Google Scholar 

  • Guart A, Bono-Blay F, Borrel A, Lacorte S (2014) Effect of bottling and storage on the migration of plastic constituents in Spanish bottled waters. Food Chem 156:73–80. https://doi.org/10.1016/J.FOODCHEM.2014.01.075

    Article  CAS  Google Scholar 

  • Huang PC, Lee CC (2008) Occurrence of phthalates in sediment and biota: relationship to aquatic factors and the biota-sediment accumulation factor. Chemosphere 73(4):539–544. https://doi.org/10.1016/J.CHEMOSPHERE.2008.06.019

    Article  CAS  Google Scholar 

  • Kong L, Kadokami K, Wang S, Duong HT, Chau HTC (2015) Monitoring of 1300 organic micro-pollutants in surface waters from Tianjin, North China. Chemosphere 122:125–130. https://doi.org/10.1016/j.chemosphere.2014.11.025

    Article  CAS  Google Scholar 

  • Magdouli S, Daghrir R, Brar SK, Drogui P, Tyagi RD (2013) Di 2-ethylhexylphtalate in the aquatic and terrestrial environment: a critical review. J Environ Manag 127:36–49. https://doi.org/10.1016/j.jenvman.2013.04.013

    Article  CAS  Google Scholar 

  • Paluselli A, Fauvelle V, Schmidt N, Galgani F, Net S, Sempéré R (2018) Distribution of phthalates in Marseille Bay (NW Mediterranean Sea). Sci Total Environ 621:578–587. https://doi.org/10.1016/J.SCITOTENV.2017.11.306

    Article  CAS  Google Scholar 

  • Pérez-Albaladejo E, Fernandes D, Lacorte S, Porte C (2017) Comparative toxicity, oxidative stress and endocrine disruption potential of plasticizers in JEG-3 human placental cells. Toxicol in Vitro 38:41–48. https://doi.org/10.1016/j.tiv.2016.11.003

    Article  CAS  Google Scholar 

  • Pérez-Albaladejo E, Lacorte S, Porte C (2019) Differential toxicity of alkylphenols in JEG-3 human placental cells: alteration of P450 aromatase and cell lipid composition. Toxicol Sci 167:336–346. https://doi.org/10.1093/toxsci/kfy243

    Article  CAS  Google Scholar 

  • Plastic additives for polymers (2017) https://doi.org/10.1016/S0306-3747(17)30137-9

  • Ramos S, Homem V, Alves A, Santos L (2015) Advances in analytical methods and occurrence of organic UV-filters in the environment — a review. Sci Total Environ 526:278–311. https://doi.org/10.1016/j.scitotenv.2015.04.055

    Article  CAS  Google Scholar 

  • Rocha MJ, Cruzeiro C, Reis M, Pardal MA, Rocha E (2014) Spatial and seasonal distribution of 17 endocrine disruptor compounds in an urban estuary (Mondego River, Portugal): evaluation of the estrogenic load of the area. Environ Monit Assess 186(6):3337–3350. https://doi.org/10.1007/s10661-014-3621-0

    Article  CAS  Google Scholar 

  • Salgueiro-González N, Concha-Graña E, Turnes-Carou I, Muniategui-Lorenzo S, López-Mahía P, Prada-Rodríguez D (2012) Blank and sample handling troubleshooting in ultratrace analysis of alkylphenols and bisphenol A by liquid chromatography tandem mass spectrometry. Talanta 101:413–419. https://doi.org/10.1016/J.TALANTA.2012.09.050

    Article  Google Scholar 

  • Salgueiro-González N, Muniategui-Lorenzo S, López-Mahía P, Prada-Rodríguez D (2017) Trends in analytical methodologies for the determination of alkylphenols and bisphenol A in water samples. Anal Chim Acta 962:1–14. https://doi.org/10.1016/j.aca.2017.01.035

    Article  CAS  Google Scholar 

  • Salgueiro-González N, Castiglioni S, Zuccato E, Turnes-Carou I, López-Mahía P, Muniategui-Lorenzo S (2018) Recent advances in analytical methods for the determination of 4-alkylphenols and bisphenol a in solid environmental matrices: a critical review. Anal Chim Acta 1024:39–51

    Article  Google Scholar 

  • Sánchez-Avila J, Bonet J, Velasco G, Lacorte S (2009) Determination and occurrence of phthalates, alkylphenols, bisphenol A, PBDEs, PCBs and PAHs in an industrial sewage grid discharging to a municipal wastewater treatment plant. Sci Total Environ 407:4157–4167

    Article  Google Scholar 

  • Schirinzia GF, Köck-Schulmeyer M, Cabrera M, González-Fernández D, Hanke G, Farré M, Barceló D (2020) Riverine anthropogenic litter load to the Mediterranean Sea near the metropolitan area of Barcelona, Spain. Sci Total Environ 714:136807. https://doi.org/10.1016/j.scitotenv.2020.136807

    Article  CAS  Google Scholar 

  • Sheikh IA, Beg MA (2019) Structural characterization of potential endocrine disrupting activity of alternate plastic additives di-(2-ethylhexyl) adipate (DEHA), acetyl tributyl citrate (ATBC) and 2,2,4-trimethyl 1,3-pentanediol diisobutyrate (TPIB) with human sex hormone-binding globulin. Reprod Toxicol 83:46–53

    Article  CAS  Google Scholar 

  • Wagner M, Scherer C, Alvarez-Muñoz D, Brennholt N, Bourrain X, Buchinger S, Fries E, Grosbois C, Klasmeier J, Marti T, Rodriguez-Mozaz S, Urbatzka R, Vethaak AD, Winther-Nielsen M, Reifferscheid G (2014) Microplastics in freshwater ecosystems: what we know and what we need to know. Environ Sci Eur 26:12–20

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Environmental Chemistry, IDAEA-CSIC, Jordi Girona 18-26, 08034, Barcelona, Catalonia, Spain

    Gabino Bolívar-Subirats, Montserrat Cortina-Puig & Sílvia Lacorte

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  1. Gabino Bolívar-Subirats
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  2. Montserrat Cortina-Puig
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  3. Sílvia Lacorte
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Correspondence to Sílvia Lacorte.

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Responsible editor: Philippe Garrigues

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Bolívar-Subirats, G., Cortina-Puig, M. & Lacorte, S. Multiresidue method for the determination of high production volume plastic additives in river waters. Environ Sci Pollut Res 27, 41314–41325 (2020). https://doi.org/10.1007/s11356-020-10118-2

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  • DOI: https://doi.org/10.1007/s11356-020-10118-2

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