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Developmental toxicity of carbon nanoparticles during embryogenesis in chicken

  • Nanotechnology, Nanopollution, Nanotoxicology and Nanomedicine (NNNN)
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Abstract

Nanoparticles (NPs) are very small particles present in a wide range of materials. There is a dearth of knowledge regarding their potential secondary effects on the health of living organisms and the environment. Increasing research attention, however, has been directed toward determining the effects on humans exposed to NPs in the environment. Although the majority of studies focus on adult animals or populations, embryos of various species are considered more susceptible to environmental effects and pollutants. Hence, research studies dealing mainly with the impacts of NPs on embryogenesis have emerged recently, as this has become a major concern. Chicken embryos occupy a special place among animal models used in toxicity and developmental investigations and have also contributed significantly to the fields of genetics, virology, immunology, cell biology, and cancer. Their rapid development and easy accessibility for experimental observance and manipulation are just a few of the advantages that have made them the vertebrate model of choice for more than two millennia. The early stages of chicken embryogenesis, which are characterized by rapid embryonic growth, provide a sensitive model for studying the possible toxic effects on organ development, body weight, and oxidative stress. The objective of this review was to evaluate the toxicity of various types of carbon black nanomaterials administered at the beginning of embryogenesis in a chicken embryo model. In addition, the effects of diamond and graphene NPs and carbon nanotubes are reviewed.

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Acknowledgments

The authors extend thanks to their respective institutes and universities.

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Authors and Affiliations

  1. Department of Veterinary Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, Egypt

    Dalia H. Samak & Yasser S. El-Sayed

  2. Department of Pharmacology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, Egypt

    Hazem M. Shaheen

  3. Department of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, Egypt

    Ali H. El-Far

  4. Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt

    Mohamed E. Abd El-Hack

  5. Department of Histology and Cytology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, Egypt

    Ahmed E. Noreldin

  6. Department of Nutrition and Veterinary Clinical Nutrition, Faculty of Veterinary Medicine, Alexandria University, Edfina, 22758, Egypt

    Karima El-Naggar

  7. Department of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt

    Sameh A. Abdelnour

  8. Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt

    Essa M. Saied

  9. Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom, Egypt

    Hesham R. El-Seedi

  10. Pharmacognosy Group, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden

    Hesham R. El-Seedi

  11. Chrono-Environment Laboratory, UMR CNRS 6249, Bourgogne Franche-Comté University, 25030, Besançon Cedex, France

    Lotfi Aleya

  12. Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt

    Mohamed M. Abdel-Daim

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  1. Dalia H. Samak
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  2. Yasser S. El-Sayed
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  3. Hazem M. Shaheen
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  4. Ali H. El-Far
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  5. Mohamed E. Abd El-Hack
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  6. Ahmed E. Noreldin
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  7. Karima El-Naggar
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  8. Sameh A. Abdelnour
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  10. Hesham R. El-Seedi
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  11. Lotfi Aleya
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  12. Mohamed M. Abdel-Daim
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Correspondence to Mohamed E. Abd El-Hack.

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Samak, D.H., El-Sayed, Y.S., Shaheen, H.M. et al. Developmental toxicity of carbon nanoparticles during embryogenesis in chicken. Environ Sci Pollut Res 27, 19058–19072 (2020). https://doi.org/10.1007/s11356-018-3675-6

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