Skip to main content
SpringerLink
Log in

Feasibility of Nondestructive Measurement of 3D Vascular Intramural Strains by Optical Coherence Elastography Based on Distortion Correction and Digital Volume Correlation

  • Research paper
  • Published:
Experimental Mechanics Aims and scope Submit manuscript

Abstract

Background

The displacements and strains in the cylindrical coordinate system provide information easier to correlate to the pathologic feature of the tubular blood vessel than those in the Cartesian coordinate system. However, distortions and speckle decorrelation have obstructed accurate vascular strain measurement.

Objective

This study is to introduce an improved optical coherence elastography (OCE) method based on digital volume correlation (DVC) and correction of distortions to measure the full-field vascular deformation.

Methods

Refractive index normalization together with refractive distortion correction based on the Fermat’s principle was proposed to recover the actual shape of the vascular wall imaged by optical coherence tomography (OCT). Meanwhile, the displacement fields calculated by DVC were also corrected. The cylindrical coordinate system was created with the origin at the central line of the vascular phantom or sample. Then the full-field 3D displacements in cylindrical coordinates were obtained through coordinate transformation and strains were calculated.

Results

A vascular phantom and a porcine artery inflated from 80 mmHg to 85 mmHg were measured. 3D intramural displacements and strains were obtained. The absolute difference between the measured and theoretically calculated strains of the phantom is less than 0.2%. The standard deviation is less than 0.2% as well. A stripe is shown on the radial strain image, which is consistent with the feature of the layered structure.

Conclusions

To the best of our knowledge, this is the first experimental study of the 3D intramural vascular deformation under inflation. The proposed DVC-OCE method based on distortion correction and coordinate transformation has the potential to be further developed as an effective full-field nondestructive measurement method of vascular mechanics.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13

Similar content being viewed by others

Data Availability

The data that support the findings of this study are available from the corresponding author upon reasonable request.

References

  1. Xu L, Cao T, Liu X, Zhang L, Wang J, Chen S, Liu J, Duan Y (2010) The value of vascular circumferential strain in evaluating carotid elasticity in patients with hypertension. Chin J Ultrasonogr 19(10):842–845 (in Chinese)

    Google Scholar 

  2. Larin KV, Sampson DD (2017) Optical coherence elastography-OCT at work in tissue biomechanics. Biomed Opt Express 8(2):1172–1202

    Article  Google Scholar 

  3. Marrese M, Antonovaite N, Nelemans BKA, Smit TH, Iannuzzi D (2019) Micro-indentation and optical coherence tomography for the mechanical characterization of embryos: experimental setup and measurements on chicken embryos. Acta Biomater 97:524–534

    Article  Google Scholar 

  4. Sun C, Standish B, Yang VX (2011) Optical coherence elastography: current status and future applications. J Biomed Opt 16(4):1–13

    Article  Google Scholar 

  5. Giuseppe MD, Zingales M, Pasta S, Avril S (2021) In vitro measurement of strain localization preceding dissection of the aortic wall subjected to radial tension. Exp Mech 61:119–130

    Article  Google Scholar 

  6. Acosta Santamaría VA, Flechas García M, Molimard J, Avril S (2018) Three-dimensional full-field strain measurements across a whole porcine aorta subjected to tensile loading using optical coherence tomography-digital volume correlation. Front Mech Eng 4(3):1–14

  7. Santamaria VAA, Garcia MF, Molimard J, Avril S (2020) Characterization of chemoelastic effects in arteries using digital volume correlation and optical coherence tomography. Acta Biomater 102:127–137

    Article  Google Scholar 

  8. Pillalamarri NR, Patnaik SS, Piskin S, Gueldner P, Finol EA (2021) Ex vivo regional mechanical characterization of porcine pulmonary arteries. Exp Mech 61(1):285–303

    Article  Google Scholar 

  9. Teng ZZ, Zhang YX, Huang Y, Feng JX, Yuan JM, Lu QS, Sutcliffe MPF, Brown AJ, Jing ZP, Gillard JH (2014) Material properties of components in human carotid atherosclerotic plaques: a uniaxial extension study. Acta Biomater 10(12):5055–5063

    Article  Google Scholar 

  10. Sommer G, Regitnig P, Költringer L, Holzapfel GA (2010) Biaxial mechanical properties of intact and layer-dissected human carotid arteries at physiological and supraphysiological loadings. AJP Heart Circ Physiol 298(3):H898-912

    Article  Google Scholar 

  11. Brunet J, Pierrat B, Adrien J, Maire E, Curt N, Badel P (2020) A novel method for in vitro 3D imaging of dissecting pressurized arterial segments using x-ray microtomography. Exp Mech 61(1):147–157

    Article  Google Scholar 

  12. Arévalo L, Palero V, Lobera J, Andrés N, Arroyo MP (2015) Combining endoscopes with PIV and digital holography for the study of vessel model mechanics. Meas Sci Technol 26(11):115701

  13. Korte CLD, Steen AFWVD, Céspedes EI, Pasterkamp G, Carlier SG, Mastik F, Schoneveld AH, Serruys PW, Bom N (2000) Characterization of plaque components and vulnerability with intravascular ultrasound elastography. Phys Med Biol 45(6):1465–1475

    Article  Google Scholar 

  14. Korte CLD, Steen AFWVD (2002) Intravascular ultrasound elastography: an overview. Ultrasonics 40(1–8):859–865

    Article  Google Scholar 

  15. Schaar JA, Korte C, Mastik F et al (2003) Intravascular palpography for high-risk vulnerable plaque assessment. Herz 28(6):488–495

    Article  Google Scholar 

  16. Wan J, He F, Zhao Y et al (2014) Non-invasive vascular radial/circumferential strain imaging and wall shear rate estimation using video images of diagnostic ultrasound. Ultrasound Med Biol 40(3):622–636

    Article  Google Scholar 

  17. Saijo Y, Tanaka S, Owada N, Akino Y, Nitta S (2004) Tissue velocity imaging of coronary artery by rotating-type intravascular ultrasound. Ultrasonics 42(1–9):753–757

    Article  Google Scholar 

  18. Korte CLD, Carlier SG, Mastik F, Doyley MM, Steen AFWVD, Serruys PW, Bom N (2002) Morphological and mechanical information of coronary arteries obtained with intravascular elastography. Feasibility study in vivo. Eur Heart J 23(5):405–413

    Article  Google Scholar 

  19. Janssen CRM, Korte CLD, Heiden MSVD, Wapenaar CP, Steen AFWVD (2000) Angle matching in intravascular elastography. Ultrasonics 38(1–8):417–423

    Article  Google Scholar 

  20. Seong D, Ki W, Kim P et al (2022) Virtual intraoperative optical coherence tomography angiography integrated surgical microscope for simultaneous imaging of morphological structures and vascular maps in vivo. Opt Laser Eng 151:106943

    Article  Google Scholar 

  21. Tanaka M, Hirano M, Murashima K et al (2015) 1.7-µm spectroscopic spectral-domain optical coherence tomography for imaging lipid distribution within blood vessel. Opt Express 23(5):6645–6655

    Article  Google Scholar 

  22. Fu J, Haghighi-Abayneh M, Pierron F, Ruiz PD (2016) Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation. Exp Mech 56(7):1203–1217

    Article  Google Scholar 

  23. Meng F, Chen C, Hui S, Wang J, Feng Y, Sun C (2019) Three-dimensional static optical coherence elastography based on inverse compositional Gauss-Newton digital volume correlation. J Biophoton 12(9):e201800422

  24. Lan H, Min LQ (2012) Improved snake model algorithm with application in liver image segmentation. Appl Mech Mater 263–266:2643–2648

  25. Kang K, Weitzel WF, Rubin JM et al (2004) Vascular intramural strain imaging using arterial pressure equalization. Ultrasound Med Biol 30(6):761–771

    Article  Google Scholar 

  26. Peycheva MV, Zahariev ZI, Velkova KG et al (2019) Characteristics of unstable carotid plaques - new image modalities. Folia Med 61(1):26–33

    Article  Google Scholar 

  27. Bu RF, Balakrishnan S, Price H, Zdanski C, Mitran S, Oldenburg AL (2019) Localized compliance measurement of the airway wall using anatomic optical coherence elastography. Opt Express 27(12):16751–16766

    Article  Google Scholar 

Download references

Acknowledgements

The work was supported by the National Natural Science Foundation of China (Nos. 11972249, 11872267, 11890680, 12021002), and Tianjin Science and Technology Planning Project (No. 20jczdjc00760).

Author information

Authors and Affiliations

  1. Department of Mechanical Engineering, Tianjin Key Laboratory of Modern Engineering Mechanics, Tianjin University, No.135 Yaguan Road, Tianjin, 300354, China

    J. Chen, H. Wang, H. Zhang, Q. Guo, X. Lin, H. Liu & C. Sun

Authors
  1. J. Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Q. Guo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. X. Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. H. Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. C. Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to C. Sun.

Ethics declarations

Conflict of Interest

The authors declare no conflict of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chen, J., Wang, H., Zhang, H. et al. Feasibility of Nondestructive Measurement of 3D Vascular Intramural Strains by Optical Coherence Elastography Based on Distortion Correction and Digital Volume Correlation. Exp Mech 63, 915–923 (2023). https://doi.org/10.1007/s11340-023-00960-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11340-023-00960-z

Keywords

Search

Navigation