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Mandibular advancement devices used with morning occlusal guides for treating obstructive sleep apnea—changed incisor inclination and its associated factors

  • Dentistry • Original Article
  • Published:
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Abstract

Purpose

Mandibular advancement devices (MADs) effectively treat patients with obstructive sleep apnea (OSA). Although the use of morning occlusal guides (MOGs) along with MADs is recommended to prevent dental side effects, there is no evidence to support this. The aim of this study was to evaluate the change in incisor inclination in patients with OSA treated with MADs and MOGs, and to identify its predictive factors.

Methods

Patients with OSA who received MAD and MOG therapy and had a reduction in their apnea–hypopnea index greater than 50% were analyzed. Cephalometric measurements were performed at baseline and at a 1-year follow-up or longer to assess the dentoskeletal side effects of MAD/MOG treatment. Multivariable linear regression analysis was used to assess the association between the change in incisor inclination and the independent variables that may cause the observed side effects.

Results

Among 23 patients enrolled in the study, there was significant upper incisor retroclination (U1-SN: 2.83° ± 2.68°, U1-PP: 2.86° ± 2.46°; P < 0.05) and significant lower incisor proclination (L1-SN: 3.04° ± 3.29°, L1-MP: 1.74° ± 3.13°; P < 0.05). However, no significant skeletal changes were observed. Multivariable linear regression revealed that advancement ≥ 95% of the patients’ maximal mandibular protrusion was associated with greater upper incisor retroclination. Increased treatment duration was also associated with increased upper incisor retroclination. No \measured variables were associated with the change in lower incisor inclination.

Conclusions

Dental side effects occurred in patients who used MADs with MOGs. The amount of mandibular protrusion by MADs and treatment duration were predictive factors associated with upper incisor retroclination.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Funding

This study was supported by Faculty Research Grant (DRF63024), Faculty of Dentistry, Chulalongkorn University.

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Authors and Affiliations

  1. Department of Orthodontics, Faculty of Dentistry, Chulalongkorn University, Henri-Dunant Road, Wangmai, Patumwan, Bangkok, 10330, Thailand

    Prapaporn Zheng & Chidsanu Changsiripun

  2. Department of Oral Diagnostic Science, Faculty of Dentistry, Prince of Songkla University, Kanjanavanich Road, Hat Yai, Songkhla, 90110, Thailand

    Premthip Chalidapongse

  3. Dental Center, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Rama 4 Road, Patumwan, Bangkok, 10330, Thailand

    Premthip Chalidapongse

Authors
  1. Prapaporn Zheng
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  2. Premthip Chalidapongse
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  3. Chidsanu Changsiripun
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Corresponding author

Correspondence to Chidsanu Changsiripun.

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Ethics approval

The Institutional Review Board of the Faculty of Medicine, Chulalongkorn University and the Faculty of Dentistry, Prince of Songkla University, approved the study protocol (approval number 432/63 and EC6304-1010, respectively).

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Informed consent was obtained from every participant in the study.

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The authors declare no competing interests.

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Zheng, P., Chalidapongse, P. & Changsiripun, C. Mandibular advancement devices used with morning occlusal guides for treating obstructive sleep apnea—changed incisor inclination and its associated factors. Sleep Breath 27, 2059–2067 (2023). https://doi.org/10.1007/s11325-023-02796-2

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  • DOI: https://doi.org/10.1007/s11325-023-02796-2

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