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Evaluating the performance of five scoring systems for prescreening obstructive sleep apnea-hypopnea syndrome

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Abstract

Purpose

A comparison of all scoring systems used for screening for obstructive sleep apnea-hypopnea syndrome (OSAHS) is lacking. The aim of this investigation was to evaluate the performance of five scoring systems for screening for OSAHS, as well as to validate the use of the NoSAS and SACS in the Chinese population.

Methods

Data were retrospectively collected from hospital-based, manned, overnight sleep monitoring studies for 105 consecutive outpatients using a portable monitor (PM) device.

Results

The 105 participants had an average age of 46 years and were mostly men (75%). STOP-Bang, SACS, and NoSAS scoring exhibited moderate predictive values at different AHI cutoffs (AUC 0.761–0.853, 0.722–0.854, and 0.724–0.771 respectively), followed by the STOP and Berlin questionnaire (AUC 0.680–0.781vs 0.624–0.724). Both STOP-Bang and SACS showed excellent sensitivity (89.5–100% vs 93.4–94.6%) and negative predictive value (68–100% vs 77.3–90.9%), while STOP-Bang, STOP, and SACS showed low negative likelihood ratios (− LR) (0–0.2).

Conclusions

Our study indicated that the STOP-Bang questionnaire and the SACS both show better predictive value than other scoring systems among the five screening tools for OSAHS. Both scoring systems are simple and easy to implement for screening for OSAHS in the community and in hospitals.

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Data Availability

The data supporting the findings of the article is available from the corresponding author by request. Statistical analyses were performed using SPSS v25.0 and GraphPad Prism v8.0.2.

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Acknowledgments

We thank the international research fund of Philips-Respironics for supporting us with portable sleep monitoring devices.

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Authors and Affiliations

  1. Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Wenjing Wang, Jehane Michael Le Grange, Haiying Zheng & Jinnong Zhang

  2. Department of Emergency Medicine, Renmin Hospital of Wuhan University, Wuhan, 430022, China

    Shan Yuan

  3. Department of Emergency Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Tianci Yao

  4. Salt Lake Regional Medical Center, Heart and Lung Institute of Utah, Salt Lake City, UT, 84108, USA

    Wei Peng

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  1. Wenjing Wang
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Contributions

Jinnong Zhang, Wenjing Wang, and Wei Peng conceived and designed the study. Jinnong Zhang supervised the overall study. Shan Yuan collected sleep data. Haiying Zheng and Tianci Yao conducted sleep test and questionnaire survey. Wenjing Wang analyzed the data. Jinnong Zhang and Wenjing Wang wrote the manuscript. Jinnong Zhang, Wenjing Wang, and Jehane Michael Le Grange revised the manuscript.

Corresponding author

Correspondence to Jinnong Zhang.

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The authors declare that they have no conflict of interest.

Ethical approval

This study was approved by the Medical Ethics Committee of Tongji Medical College, Huazhong University of Science and Technology and performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. Written informed consent was waived by the Medical Ethics Committee.

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Wang, W., Yuan, S., Le Grange, J. et al. Evaluating the performance of five scoring systems for prescreening obstructive sleep apnea-hypopnea syndrome. Sleep Breath 25, 1685–1692 (2021). https://doi.org/10.1007/s11325-020-02227-6

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