Skip to main content

Advertisement

Log in

Use of CPAP in patients with obstructive sleep apnea admitted to the general ward: effect on length of stay and readmission rate

  • Epidemiology • Original Article
  • Published:
Sleep and Breathing Aims and scope Submit manuscript

Abstract

Background

Obstructive sleep apnea (OSA) has been associated with multiple cardiovascular comorbidities. Despite increased awareness of OSA and its treatments, the management of OSA in the hospital setting remains below expectations.

Methods

We retrospectively reviewed the demographics, clinical characteristics, and hospital course on 413 consecutive patients with a history of OSA on domiciliary CPAP therapy admitted to the general medical ward and analyzed the prevalence of CPAP use and its effect on length of stay (LOS), 30-day readmission rate, and time-to-readmission in our tertiary care teaching hospital.

Results

Of the 413 study participants, 264 (64.0 %) patients were receiving CPAP during their hospital admission. Patients who were receiving CPAP therapy during their hospitalization had a significantly higher body mass index (BMI) (41.4 vs. 36.8 kg/m2, p < 0.001) and were more likely to be African-American (p = 0.01) and have congestive heart failure (CHF) (42.0 vs. 31.0 %, p = 0.038) peripheral vascular disease (PVD) (26.0 vs. 15.0 %, p = 0.013), and uncomplicated diabetes mellitus (p = 0.001) than those who were not. CPAP therapy in the hospital setting did not affect LOS (4.7 vs. 4.0 days, p = 0.291), readmission rate (11.0 % for both groups), or time-to-readmission (20.8 vs. 22.3 days, p = 0.762).

Conclusion

The majority of patients who are on domiciliary CPAP therapy were receiving CPAP therapy while admitted to the general medical ward of a tertiary care academic hospital. Presence of comorbid conditions such as obesity and certain cardiovascular diseases may have increased the likelihood of prescribing CPAP therapy while in the hospital. In-hospital CPAP therapy did not appear to significantly influence short-term outcomes such as hospital LOS, readmission rate, or time-to-readmission.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Lee W, Nagubadi S, Kryger MH, Mokhlesi B (2008) Epidemiology of obstructive sleep apnea: a population-based perspective. Expert Review of Respiratory Medicine 2(3):349–364. doi:10.1586/17476348.2.3.349

    Article  PubMed  PubMed Central  Google Scholar 

  2. Ye L, Pien GW, Ratcliffe SJ, Bjornsdottir E, Arnardottir ES, Pack AI, Benediktsdottir B, Gislason T (2014) The different clinical faces of obstructive sleep apnoea: a cluster analysis. The European Respiratory Journal 44(6):1600–1607. doi:10.1183/09031936.00032314

    Article  PubMed  Google Scholar 

  3. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328(17):1230–1235

    Article  CAS  PubMed  Google Scholar 

  4. Peppard PE, Young, T., Barnet, J. H., Palta, M., Hagen, E. W., Hla, K. M. (2013) Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 177(9):1006–1014. doi:10.1093/aje/kws342

  5. Bue AL, Salvaggio A, Isidoro SI, Romano S, Marrone O, Insalaco G (2014) Usefulness of reinforcing interventions on continuous positive airway pressure compliance. BMC Pulmonary Medicine 14:78. doi:10.1186/1471-2466-14-78

    Article  PubMed  PubMed Central  Google Scholar 

  6. Ou Q, Chen Y, Zhuo S, Tian X, He C, Lu X, Gao X (2015) Continuous positive airway pressure treatment reduces mortality in elderly patients with moderate to severe obstructive severe sleep apnea: a cohort study. PLoS one 10(6)

  7. Kanimozhi S, Balaji C, Saravanan A, K KR (2015) Effect of short term CPAP therapy in obstructive sleep apnea patients with metabolic syndrome. J Clin Diagn Res 9(4):cc7-cc10

  8. Fleetham J, Ayas N, Bradley D, Ferguson K, Fitzpatrick M, George C, Hanly P, Hill F, Kimoff J, Kryger M, Morrison D, Series F, Tsai W (2006) Canadian Thoracic Society guidelines: diagnosis and treatment of sleep disordered breathing in adults. Can Respir J 13(7):387–392

    Article  PubMed  PubMed Central  Google Scholar 

  9. Durán-Cantolla J, Aizpuru F, Montserrat J, Ballester E, Terán-Santos J, Aguirregomoscorta J, Gonzalez M, Lloberes P, Masa J, Peña MDL, Carrizo S, Mayos M, Barbé F (2010) Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: randomised controlled trial. BMJ 341:c5991

    Article  PubMed  Google Scholar 

  10. Hussain SF, Irfan M, Waheed Z, Alam N, Mansoor S, Islam M (2014) Compliance with continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea among privately paying patients- a cross sectional study. BMC Pulmonary Medicine 14:188. doi:10.1186/1471-2466-14-188

    Article  PubMed  PubMed Central  Google Scholar 

  11. Spurr KF, Graven MA, Gilbert RW (2008) Prevalence of unspecified sleep apnea and the use of continuous positive airway pressure in hospitalized patients, 2004 National Hospital Discharge Survey. Sleep & Breathing = Schlaf & Atmung 12(3):229–234. doi:10.1007/s11325-007-0166-2

    Article  Google Scholar 

  12. Sorscher AJ, Caruso EM (2012) Frequency of provision of CPAP in the inpatient setting: an observational study: "CPAP provision in the inpatient setting". Sleep & Breathing = Schlaf & Atmung 16(4):1147–1150. doi:10.1007/s11325-011-0621-y

    Article  Google Scholar 

  13. Spurr K, Morrison D, Graven M, Webber A, Gilbert R (2010) Analysis of hospital discharge data to characterize obstructive sleep apnea and its management in adult patients hospitalized in Canada: 2006 to 2007. Can Respir J 17(5):213–218

    Article  PubMed  PubMed Central  Google Scholar 

  14. Proczko MA, Stepaniak PS, de Quelerij M, van der Lely FH, Smulders JF, Kaska L, Soliman Hamad MA (2014) STOP-bang and the effect on patient outcome and length of hospital stay when patients are not using continuous positive airway pressure. J Anesth 28(6):891–897. doi:10.1007/s00540-014-1848-0

    Article  PubMed  PubMed Central  Google Scholar 

  15. Mutter TC, Chateau, D., Moffatt, M., Ramsey, C., Roos, L. L., Kryger, M. (2014) A matched cohort study of postoperative outcomes in obstructive sleep apnea: could preoperative diagnosis and treatment prevent complications? Anesthesiology 121(4):707–718. doi:10.1097/aln.0000000000000407

  16. Abdelsattar ZM, Hendren, S., Wong, S. L., Campbell, D. A., Jr., Ramachandran, S. K. (2015) The impact of untreated obstructive sleep apnea on cardiopulmonary complications in general and vascular surgery: a cohort study. Sleep 38(8):1205–1210. doi:10.5665/sleep.4892

  17. Nagappa M, Mokhlesi, B., Wong, J., Wong, D. T., Kaw, R., Chung, F. (2015) The effects of continuous positive airway pressure on postoperative outcomes in obstructive sleep apnea patients undergoing surgery: a systematic review and meta-analysis. Anesth Analg 120(5):1013–1023. doi:10.1213/ane.0000000000000634

  18. Miguel-Díez Jd, Carrasco-Garrido P, Jiménez-García R, Puente-Maestu L, Hernández-Barrera V, Andrés ALd (2015) Obstructive sleep apnea among hospitalized patients in Spain, analysis of hospital discharge datas 2008–2012. Sleep & breathing = Schlaf & Atmung. doi:10.1007/s11325–014-1104-8

  19. Charlson M, Pompei P, Ales K, MacKenzie C (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373–383

    Article  CAS  PubMed  Google Scholar 

  20. Charlson M, Szatrowski T, Peterson J, Gold J (1994) Validation of a combined comorbidity index. J Clin Epidemiol 47(11):1245–1251

    Article  CAS  PubMed  Google Scholar 

  21. Smith DF, Spiceland CP, Pringle LC, Mattare KL, Benke JR, Ishman SL (2014) Financial incentive of home continuous positive airway pressure machine use in the inpatient hospital setting. Laryngoscope 124(9):2200–2204. doi:10.1002/lary.24604

    Article  PubMed  Google Scholar 

  22. Holmqvist F, Guan N, Zhu Z, Kowey PR, Allen LA, Fonarow GC, Hylek EM, Mahaffey KW, Freeman JV, Chang P, Holmes DN, Peterson ED, Piccini JP, Gersh BJ (2015) Impact of obstructive sleep apnea and continuous positive airway pressure therapy on outcomes in patients with atrial fibrillation—results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF). American heart journal 169(5):647–654.e642. doi:10.1016/j.ahj.2014.12.024

  23. Nishihata Y, Takata Y, Usui Y, Kato K, Yamaguchi T, Shiina K, Yamashina A (2015) Continuous positive airway pressure treatment improves cardiovascular outcomes in elderly patients with cardiovascular disease and obstructive sleep apnea. Heart Vessel 30(1):61–69. doi:10.1007/s00380-013-0451-x

    Article  Google Scholar 

  24. Kasai T, DYumino, Redolfi S, Su MC, Ruttanaumpawan P, Mak S, Newton GE, Floras JS, Bradley TD (2015) Overnight effects of obstructive sleep apnea and its treatment on stroke volume in patients with heart failure. The Canadian Journal of Cardiology 31(7):832–838. doi:10.1016/j.cjca.2015.01.001

  25. Khayat R, Jarjoura D, Porter K, Sow A, Wannemacher J, Dohar R, Pleister A, Abraham WT (2015) Sleep disordered breathing and post-discharge mortality in patients with acute heart failure. Eur Heart J 36(23):1463–1469. doi:10.1093/eurheartj/ehu522

    Article  PubMed  PubMed Central  Google Scholar 

  26. Kauta SR, Keenan BT, Goldberg L, Schwab RJ (2014) Diagnosis and treatment of sleep disordered breathing in hospitalized cardiac patients: a reduction in 30-day hospital readmission rates. Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy Of Sleep Medicine 10(10):1051–1059. doi:10.5664/jcsm.4096

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. Kamel.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

No ethical approval was required for this study.

Funding

No funding was received for this research.

Informed consent

No informed consent was required for this study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kamel, G., Munzer, K. & Espiritu, J. Use of CPAP in patients with obstructive sleep apnea admitted to the general ward: effect on length of stay and readmission rate. Sleep Breath 20, 1103–1110 (2016). https://doi.org/10.1007/s11325-016-1328-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11325-016-1328-x

Keywords

Navigation