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Radiological evaluation of the periosteal reactions in the jaws: a retrospective CBCT study

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Abstract

Objectives

The objective of this study is to evaluate the relationship between the radiological features of periosteal reactions (PR) and histopathological features of the lesions.

Methods

A total of 4605 CBCT images were evaluated and they were classified according to their radiological differential diagnosis. Images with pathologies were listed according to their histopathological examinations as cystic lesions, benign tumours, malignant tumours, fibro-osseous lesions and osteonecrosis, while images without pathologies were listed as traumas and others. All groups were reclassified as with or without the presence of detected PR.

Results

Pathologies and traumas were detected in 1801 of 4605 patients. There were 3 PR in 1140 cystic lesions, 4 PR in 102 benign tumours, 16 PR in 43 malignant tumours, 67 PR in 156 osteonecrosis/osteomyelitis cases and 3 PR in 262 trauma cases. As a result of the chi-square test between groups, there was a significant relationship between histopathologic diagnoses and periosteal reaction patterns (p = 0.000).

Conclusions

Although there is a significant overlap between the patterns of PRs, PRs can be used to narrow the possibilities in the differential diagnosis. However, PRs alone are not sufficient variables for differential diagnosis in the absence of cortical bone destruction, localization, clinical and systemic findings.

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Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Department of Dentomaxillofacial Radiology, Istanbul University, Istanbul, Turkey

    Gürkan Ünsal & İlknur Özcan

  2. Institute of Graduate Studies in Health Sciences, Istanbul University, Istanbul, Turkey

    Gürkan Ünsal

  3. Institute of Oncology, Department of Tumour Pathology, Istanbul University, Istanbul, Turkey

    Merva Soluk-Tekkeşin

  4. Department of Oral and Maxillofacial Surgery, Istanbul University, Istanbul, Turkey

    Kıvanç Bektaş-Kayhan

Authors
  1. Gürkan Ünsal
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  2. Merva Soluk-Tekkeşin
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  3. Kıvanç Bektaş-Kayhan
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  4. İlknur Özcan
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Correspondence to Gürkan Ünsal.

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Conflict of interest statement

Gürkan Ünsal, Merva Soluk-Tekkeşin, Kıvanç Bektaş-Kayhan and İlknur Özcan declare that they have no conflict of interest.

Human rights statements and informed consent

All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study, file number 2018/71, was found ethically appropriate at the meeting of Istanbul University, Faculty of Dentistry, Clinical Research Ethics Committee dated 18.07.2018. Informed consent was obtained from all individual participants included in the study.

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Ünsal, G., Soluk-Tekkeşin, M., Bektaş-Kayhan, K. et al. Radiological evaluation of the periosteal reactions in the jaws: a retrospective CBCT study. Oral Radiol 38, 497–508 (2022). https://doi.org/10.1007/s11282-021-00580-0

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  • DOI: https://doi.org/10.1007/s11282-021-00580-0

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