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Osteoporotic mandibular changes caused by type 2 diabetes mellitus: a comparative study by cone beam computed tomography imaging

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Abstract

Objectives

Studies on bone mineral density and fracture risk in diabetic patients have attracted interest in the last few years. This study was aimed at comparing mandibular osteoporotic changes assessed by qualitative and quantitative radiographic methods in the mandibles of type 2 diabetes mellitus patients with those of non-diabetic subjects using cone beam computed tomographic images.

Methods

This quantitative and qualitative study of mandibular bone in diabetic patients included 23 type 2 diabetes mellitus patients and an equal number of healthy subjects. Radiomorphometric measurements were performed for each subject using cone beam computed tomography images. Changes in cortical bone thickness were determined by measuring bone area. Fractal dimension analysis was applied to evaluate the trabecular structure of the bone.

Results

No statistically significant difference could be established between the type 2 diabetes mellitus group and the control group in regard to either radiomorphometric measurements or fractal dimension analysis. Quantitative assessment of mandibular bone indicated a thinning of the cortical bone, with a statistically significant difference between the type 2 diabetes mellitus patients and the healthy controls.

Conclusions

Bone condition related to diabetes involves complex pathophysiological mechanisms; thus, radiographic imaging parameters may be useful as an adjunct to clinical parameters.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Karadeniz Technical University, 64 Farabi St, 61080, Trabzon, Turkey

    Saadettin Kayipmaz, Saliha Akçay & Ömer Said Sezgin

Authors
  1. Saadettin Kayipmaz
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  2. Saliha Akçay
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  3. Ömer Said Sezgin
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Correspondence to Saadettin Kayipmaz.

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Conflict of interest

Saadettin Kayıpmaz, Saliha Akçay and Ömer Said Sezgin declare that they have no conflict of interest.

Human rights statement

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions.

Informed consent

Informed consent was obtained from all patients for being included in the study.

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Kayipmaz, S., Akçay, S. & Sezgin, Ö.S. Osteoporotic mandibular changes caused by type 2 diabetes mellitus: a comparative study by cone beam computed tomography imaging. Oral Radiol 33, 108–116 (2017). https://doi.org/10.1007/s11282-016-0252-x

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  • DOI: https://doi.org/10.1007/s11282-016-0252-x

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