Skip to main content

Advertisement

Log in

Deep Learning Approaches for Analysing Papsmear Images to Detect Cervical Cancer

  • Published:
Wireless Personal Communications Aims and scope Submit manuscript

Abstract

The main reason for leading death in female is cervical cancer. The human Papillomavirus is responsible for all cervical cancer cases. There are several diagnostic procedures to find cervical cancer that includes Pap test, liquid-based cytology, colposcopy and HPV test. Early diagnosis is crucial for successful treatment and improved survival rates. In medical image analysis, methods of deep learning are showing promising results for the identification and grading of cervical carcinoma. The work uses dataset of cervical smear images and three cutting-edge deep learning models like ResNet50V2, InceptionV3, and Xception are applied and analysed for prediction of cervical cancer. The Models are verified using cross-validation and the performance are assessed using metrics like accuracy, precision, recall, and F1 score. According to the analysis, ResNet50V2 shows the highest accuracy. The obtained results imply that without the need for invasive procedures, deep learning techniques have the ability to accurately classify cervical cancer and greatly enhance early diagnosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12

Similar content being viewed by others

Data Availability

No associated data. The study is performed on open access database.

References

  1. American Cancer Society. (2021). Cervical Cancer. Retrieved from https://www.cancer.org/cancer/cervical-cancer.html

  2. Cheng, F. H., & Hsu, N. R. (2017). A computer-aided pap smear screening system. In 2017 International Conference on Computational Science and Computational Intelligence (CSCI). IEEE, 2017.

  3. Kuko, M., & Pourhomayoun, M. (2019). An ensemble machine learning method for single and clustered cervical cell classification. In 2019 IEEE 20th International Conference on Information Reuse and Integration for Data Science (IRI). IEEE, 2019.

  4. Dillak, R. Y., & Sudarmadji, P. W. (2021) Cervical Cancer classification using elman recurrent neural network and genetic algorithm. In 2021 5th International Conference on Informatics and Computational Sciences (ICICoS). IEEE, 2021.

  5. Li, D., Zhang, Y., Liu, Q., & Hu, X. (2019). Deep learning for cervical cancer detection and classification: A review. Current Medical Imaging Reviews, 15(3), 230–237.

    Google Scholar 

  6. Erkaymaz, O., & Palabaş, T. (2018). Classification of cervical cancer data and the effect of random subspace algorithms on classification performance. In 2018 26th Signal Processing and Communications Applications Conference (SIU). IEEE, 2018.

  7. Chen, L., Wang, M., & Yang, W. (2021). Deep learning approaches for cervical cancer screening: A systematic review. Frontiers in Oncology, 11, 683160.

    Google Scholar 

  8. Zhi, L., & Carneiro, G. (2017). Evaluation of three algorithms for the segmentation of overlapping cervical cells. IEEE Journal of Biomedical and Health Informatics, 21(2), 441–450. https://doi.org/10.1109/JBHI.2016.2519686

    Article  Google Scholar 

  9. Huang, Y., Qiu, X., & Lv, W. (2019). Deep learning for cervical cancer screening: A systematic review. Journal of gynecologic oncology, 30(5), e75. https://doi.org/10.3802/jgo.2019.30.e75

    Article  Google Scholar 

  10. Omone, O. M., Gbenimachor, A. U., Kovács, L., & Kozlovszky, M. (2021) Knowledge estimation with HPV and cervical cancer risk factors using logistic regression. in 2021 IEEE 15th International Symposium on Applied Computational Intelligence and Informatics (SACI), Timisoara, Romania, pp. 000381–000386 https://doi.org/10.1109/SACI51354.2021.9465585

  11. Andersen, K. K., Kjaerulff, C. M., Larsen, L. E. B., & Andersen, L. S. (2006). Segmentation of cervical cell nuclei in high-resolution microscope images: A new algorithm and a web-based software framework. Computerized Medical Imaging and Graphics, 30(4), 231–242. https://doi.org/10.1016/j.compmedimag.2006.05.004

    Article  Google Scholar 

  12. Lee, H. S., Kim, Y. J., Kim, J. K., Kim, K. H., & Park, H. K. (2019). Cervical cancer detection using deep learning-based analysis of cytology images: A review. Journal of Clinical Medicine, 8(9), 1370.

    Google Scholar 

  13. Liu, M., Yu, L., Zhang, X., & Yu, Q. (2021). Deep learning for cervical cancer diagnosis: A systematic review and meta-analysis. Frontiers in Oncology, 11, 644672.

    Google Scholar 

  14. Elakkiya, R., Subramaniyaswamy, V., Vijayakumar, V., & Mahanti, A. (2022). Cervical cancer diagnostics healthcare system using hybrid object detection adversarial networks. IEEE Journal of Biomedical and Health Informatics, 26(4), 1464–1471. https://doi.org/10.1109/JBHI.2021.3094311. Epub 2022 Apr 14 PMID: 34214045.

    Article  Google Scholar 

  15. Das, N. R., Devi, T. H., & Singh, K. R. (2019). Automated cervical cancer detection and diagnosis using deep learning techniques: A systematic review. Journal of Ambient Intelligence and Humanized Computing, 10(5), 1989–2007.

    Google Scholar 

  16. Liu, J., Ding, L., Li, C., Yang, J., & Lin, X. (2019). Deep learning for cervical cancer diagnosis using histology images: A comprehensive review. IEEE access, 7, 66760–66777. https://doi.org/10.1109/access.2019.2918428

    Article  Google Scholar 

  17. Mehta, S., & Shukla, A. (2020). Deep learning in cervical cancer screening and diagnosis: A review. Expert Review of Anticancer Therapy, 20(8), 657–664. https://doi.org/10.1080/14737140.2020.1790926

    Article  Google Scholar 

  18. Alghamdi, N., Al-Rahbi, A., Al-Widyan, M., Alsubaie, M., & Alsharif, M. (2020). Deep learning for cervical cancer classification and segmentation: A review. Healthcare (Basel), 8(4), 449.

    Google Scholar 

  19. Kumawat, G., Vishwakarma, S. K., Chakrabarti, P., Chittora, P., Chakrabarti, T., & Lin, J. C. (2023). Prognosis of cervical cancer disease by applying machine learning techniques. Journal of Circuits, Systems and Computers, 32(01), 2350019.

    Article  Google Scholar 

  20. Saha, S. K., Banik, S., Basu, S., & Sarkar, R. (2020). Automated cervical cancer diagnosis using convolutional neural networks. Biomedical Signal Processing and Control, 55, 101644.

    Google Scholar 

  21. Srivastava, S. C., Tiwari, P., & Agarwal, S. (2020). Deep learning for cervical cancer detection: A comprehensive review. Journal of Ambient Intelligence and Humanized Computing, 11(6), 2565–2583.

    Google Scholar 

  22. Sharma, A., Mishra, A., Singh, A. K., & Anand, A. (2020). Recent advances in deep learning for cervical cancer diagnosis and classification. Journal of Ambient Intelligence and Humanized Computing, 11(6), 2451–2467.

    Google Scholar 

  23. Sharma, R., Pachori, R. B., & Acharya, U. R. (2019). Cervical cancer detection using deep learning techniques: A systematic review and meta-analysis. Computers in Biology and Medicine, 109, 1–10.

    Google Scholar 

  24. Zhang, S., et al. (2021). Deep learning for cervical cancer screening: A systematic review and meta-analysis. Frontiers in Oncology, 11, 9776. https://doi.org/10.3389/fonc.2021.659776

    Article  Google Scholar 

  25. Le Ngoc, H., & Huyen, K. V. (2023). An approach of cervical cancer diagnosis using class weighting and oversampling with Keras. TELKOMNIKA Telecommunication Computing Electronics and Control, 21(1), 142–149.

    Article  Google Scholar 

  26. Usha Rani, K., Harish, M. P., & Kumari, R. P. (2021). Automated cervical cancer detection using deep learning based on multispectral images. Journal of Ambient Intelligence and Humanized Computing, 12(4), 4201–4212.

    Google Scholar 

  27. Yadav, R. K., Garg, R., & Tiwari, A. (2021). Automated detection of cervical cancer using deep learning techniques: A review. Journal of Medical Systems, 45(3), 1–12.

    Google Scholar 

  28. Zhang, Y., et al. (2021). Deep learning for cervical cancer detection using whole-slide pathological images: A comprehensive review. Frontiers in Oncology, 11, 72242. https://doi.org/10.3389/fonc.2021.672242

    Article  Google Scholar 

  29. Chen, Y., et al. (2020). Deep learning for cervical cancer screening and diagnosis: A comprehensive review. International Journal of Environmental Research and Public Health, 17(19), 7008. https://doi.org/10.3390/ijerph17197008

    Article  Google Scholar 

  30. Zhang, X., Zhang, S., & Zhang, Q. (2019). Deep learning for cervical cancer diagnosis: A review and meta-analysis. Journal of healthcare engineering, 2019, 3642582. https://doi.org/10.1155/2019/3642582

    Article  Google Scholar 

  31. Ghoneim, A., Muhammad, G., & Hossain, M. S. (2020). Cervical cancer classification using convolutional neural networks and extreme learning machines. Future Generation Computer Systems, 102, 643–649.

    Article  Google Scholar 

  32. Alsubai, S., Alqahtani, A., Sha, M., Almadhor, A., Abbas, S., Mughal, H., & Gregus, M. (2023). Privacy preserved cervical cancer detection using convolutional neural networks applied to pap smear images. Computational and Mathematical Methods in Medicine, 8(2023), 9676206. https://doi.org/10.1155/2023/9676206.PMID:37455684;PMCID:PMC10349677

    Article  Google Scholar 

  33. Tan, S. L., Selvachandran, G., Ding, W., et al. (2024). Cervical cancer classification from pap smear images using deep convolutional neural network models. Interdiscip Sci Comput Life Sci, 16, 16–38. https://doi.org/10.1007/s12539-023-00589-5

    Article  Google Scholar 

  34. Kalbhor, M., Shinde, S., Joshi, H., & Wajire, P. (2023). Pap smear-based cervical cancer detection using hybrid deep learning and performance evaluation. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 11(5), 1615–1624. https://doi.org/10.1080/21681163.2022.2163704

    Article  Google Scholar 

  35. Rastogi, P., Khanna, K., & Singh, V. (2023). Classification of single‐cell cervical pap smear images using EfficientNet. Expert Systems. https://doi.org/10.1111/exsy.13418

    Article  Google Scholar 

  36. Priyankaa, J., & Bhadri Rajub, M. S. V. S. (2021). Machine learning approach for prediction of cervical cancer. Turkish Journal of Computer and Mathematics Education (TURCOMAT), 12, 3050–3058.

    Google Scholar 

  37. Tripathi, A. (2021) Classification of cervical cancer using deep learning algorithm. In Proceedings of the Fifth International Conference on Intelligent Computing and Control Systems (ICICCS 2021), Madurai, India, pp. 1210–1218.

  38. Singh, S. K., & Goyal, A. (2022). Performance analysis of machine learning algorithms for cervical cancer detection. In Research Anthology on Medical Informatics in Breast and Cervical Cancer, IGI Global, pp. 347–370.

  39. Madhukar, R. K., Joshi, R. C., & Dutta, M. K. (2021) A robust deep learning and feature fusion-based multi-class classification of cervical cells.

  40. Moldovan, D. (2020) Cervical cancer diagnosis using a chicken swarm optimization based machine learning method. In International Conference on eHealth and Bioengineering (EHB), IASI, Romania

  41. Alpan, K. (2021). Performance evaluation of classification algorithms for early detection of behavior determinant based cervical cancer. In 5th International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT), pp. 706–710.

Download references

Funding

No funding is associated with this study.

Author information

Authors and Affiliations

Authors

Contributions

Somasundaram Devaraj—Experimentation and supervision, Nirmala Madian*—implementation of research, result analysis, manuscript drafting, M Menagadevi—manuscript drafting and database management, R Remya—database analysis and supervision.

Corresponding author

Correspondence to Nirmala Madian.

Ethics declarations

Conflict of interest

Authors have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Devaraj, S., Madian, N., Menagadevi, M. et al. Deep Learning Approaches for Analysing Papsmear Images to Detect Cervical Cancer. Wireless Pers Commun 135, 81–98 (2024). https://doi.org/10.1007/s11277-024-10986-8

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11277-024-10986-8

Keywords

Navigation