Abstract
The microbiota represents a crucial area of research in maintaining human health due to its potential for uncovering novel biomarkers, therapies, and molecular mechanisms relevant to population identification and experimental model characterization. Among these microorganisms, Enterococcus faecalis, a Gram-positive bacterium found in the gastrointestinal tract of humans and animals, holds particular significance. Strains of this bacterial species have sparked considerable debate in the literature due to their dual nature; they can either be utilized as probiotics in the food industry or demonstrate resistance to antibiotics, potentially leading to severe illness, disability, and death. Given the diverse characteristics of Enterococcus faecalis strains, this review aims to provide a comprehensive understanding of their impact on various systems within the host, including the immunological, cardiovascular, metabolic, and nervous systems. Furthermore, we summarize the bacterium-host interaction characteristics and molecular effects to highlight their targets, features, and overall impact on microbial communities and host health.
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Acknowledgements
A.M.B. is supported by a scholarship from CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). A.M.B. was also supported with a scholarship from CAPES/PRINT for Sandwich Doctorate at Karolinska Institutet. G.S.I. is supported by a postdoctoral fellowship from CAPES/PRINT.
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A.M.B. is supported by a scholarship from CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior). A.M.B. was also supported with a scholarship from CAPES/PRINT for Sandwich Doctorate at Karolinska Institutet. G.S.I. is supported by a postdoctoral fellowship from CAPES/PRINT.
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Boeder, A.M., Spiller, F., Carlstrom, M. et al. Enterococcus faecalis: implications for host health. World J Microbiol Biotechnol 40, 190 (2024). https://doi.org/10.1007/s11274-024-04007-w
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DOI: https://doi.org/10.1007/s11274-024-04007-w