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Detrusor underactivity influences the efficacy of TURP in patients with BPO

  • Urology - Original Paper
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Abstract

Purpose

To investigate the effect of detrusor underactivity on the efficacy of TURP in patients with benign prostate obstruction.

Methods

A retrospective study of 350 patients with benign prostate obstruction who underwent TURP was carried out. Different degrees of bladder outlet obstruction were grouped by the bladder outlet obstruction index. ROC curves were used to calculate the optimal cut-off point for the bladder contractility index used to divide the DU patients into mild DU and severe DU patients. The effect of DU on the efficacy of TURP in benign prostate obstruction patients was studied by comparing the subjective and objective parameters preoperatively and 3 months postoperatively between severe DU, mild DU and non-DU benign prostate obstruction patients in two obstruction groups (20 ≤ BOOI < 40 and BOOI ≥ 40).

Results

According to the ROC curve, the optimal cut-off point for the bladder contractility index was 82; thus, 69 patients were considered mild DU patients (82 ≤ BCI < 100), 67 patients were considered severe DU patients (BCI < 82), and 214 patients were considered non-DU patients (BCI ≥ 100). Both the postoperative subjective and objective parameters of the non-DU, mild DU and severe DU patients significantly improved in two obstruction groups. However, in the 20 ≤ BOOI < 40 group, the successful improvement rates for the IPSS, IPSS-S, IPSS-V, QoL and fQmax in the severe DU patients were only 38.2%, 38.2%, 44.1%, 41.2% and 38.2%, respectively.

Conclusion

Patients with varying degrees of benign prostate obstruction can benefit from TURP, but for patients with severe DU in the 20 ≤ BOOI < 40 group, TURP should be considered only after deliberation.

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Acknowledgements

Thanks all related hospital staff and patients involved in the study.

Funding

There is not related project funding for this topic.

Author information

Author notes

  1. Yan Zhu and Yao-Rui Zhao have contributed equally to this work.

Authors and Affiliations

  1. Graduate School, Tianjin Medical University, No. 1 Guang Dong Road, Tianjin, 300203, China

    Yan Zhu & Ping Zhong

  2. Department of Urology, Characteristic Medical Center of Chinese People’s Armed Police (Original Work Unit: The Second Hospital of Tianjin Medical University and Tianjin Institute of Urology (1990.10~2013.12)), No. 220 Cheng Lin Road, Tianjin, 300162, China

    Yao-Rui Zhao

  3. Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, No. 23 Ping Jiang Road, Tianjin, 300211, China

    Bao-Min Qiao, Zhi-Qiang Yang & Yuan-Jie Niu

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  1. Yan Zhu
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  2. Yao-Rui Zhao
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Contributions

Y.Z.: Conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content and statistical analysis; Y.R.Z.: Conception and design, analysis and interpretation of data, critical revision of the manuscript for important intellectual content, administrative, technical or material support and supervision; P.Z.: Conception and design, acquisition of data and analysis and interpretation of data; B.M.Q.: Critical revision of the manuscript for important intellectual content, administrative, technical or material support and supervision; Z.Q.Y.: Acquisition of data, administrative, technical or material support; Y.J.N.: Acquisition of data, administrative, technical or material support; All authors read and approved the final manuscript.

Corresponding author

Correspondence to Yao-Rui Zhao.

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The authors have no relevant financial or non-financial interests to disclose.

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This is an observational study. The Research Ethics Committee has confirmed that no ethical approval is required.

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Verbal informed consent was obtained prior to the interview.

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Zhu, Y., Zhao, YR., Zhong, P. et al. Detrusor underactivity influences the efficacy of TURP in patients with BPO. Int Urol Nephrol 53, 835–841 (2021). https://doi.org/10.1007/s11255-020-02750-1

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  • DOI: https://doi.org/10.1007/s11255-020-02750-1

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