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Chromatographic Separation of Racemates of Alcohols Using Porous Coordination Compounds of Zinc and Vanadium(IV) with Lactate and β-Cyclodextrin

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It was shown that the efficiency of chromatographic separation of the racemates of 2-butanol, 2-hexanol, 3-hexanol, and 1-phenylethanol on columns with coordination compounds [Zn2(bdc)(S-Lact)(DMF)]n (bdc2– = 1,4-benzenedicarboxylate, S-Lact– = (S)-lactate) and Na7{(VO)7Na7(H2O)7(β-CD)2} (β-CD = β-cyclodextrin) does not depend on the size of the alcohol molecule. It was found that in the case of the 1-phenylethanol racemate separation with [Zn2(bdc)(S-Lact)(DMF)]n the enantiomeric excess of the alcohol varies inversely with the viscosity of the solvent.

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Authors and Affiliations

  1. L. V. Pysarzhevsky Institute of Physical Chemistry, National Academy of Sciences of Ukraine, Prospekt Nauky, 31, Kyiv, 03028, Ukraine

    Yu. A. Satska, R. A. Polunin & S. V. Kolotilov

  2. Enamine Ltd., Vul. Oleksandra Matrosova, 23, Kyiv, 01103, Ukraine

    N. P. Komarova, K. S. Gavrilenko & O. V. Manoylenko

  3. ChembioCenter, National Taras Shevchenko University of Kyiv, Vul. Chervonotkats’ka, 61, Kyiv, 02094, Ukraine

    K. S. Gavrilenko

Authors
  1. Yu. A. Satska
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  2. N. P. Komarova
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  3. K. S. Gavrilenko
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  4. R. A. Polunin
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  5. O. V. Manoylenko
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  6. S. V. Kolotilov
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Correspondence to Yu. A. Satska.

Additional information

Translated from Teoreticheskaya i Éksperimental’naya Khimiya, Vol. 53, No. 3, pp. 192-197, May-June, 2017.

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Satska, Y.A., Komarova, N.P., Gavrilenko, K.S. et al. Chromatographic Separation of Racemates of Alcohols Using Porous Coordination Compounds of Zinc and Vanadium(IV) with Lactate and β-Cyclodextrin. Theor Exp Chem 53, 204–209 (2017). https://doi.org/10.1007/s11237-017-9517-7

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  • DOI: https://doi.org/10.1007/s11237-017-9517-7

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