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Surface Plasmon Resonance Sensors: Methods of Surface Functionalization and Sensitivity Enhancement

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Theoretical and Experimental Chemistry Aims and scope

Surface plasmon resonance (SPR) has proven to be an exceedingly powerful technique for real-time monitoring of biomolecular reactions. Methods for the immobilization of biomolecules on the surface of SPR sensors and graphene are surveyed. Approaches are offered for functionalization of the surface of nanoparticles used for the excitation of local SPR (LSPR). Examples are examined for the amplification of SPR by the combined use of metal nanoparticles and graphene. The feasibility of combining SPR and electrochemical methods was demonstrated.

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Notes

  1. Small nucleic acid molecules, which may act as highly specific receptors of low-molecular-weight organic compounds.

  2. Tropism is the orientation reaction of a cell, i.e., the direction of growth or movement of cells relative to an irritant.

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The authors express their gratitude to G. V. Beketov for a useful discussion of this work. Dr. Shynkarenko thanks the Swiss National Science Fund (Berne, SNSF) for support and partial financing of the present work in Project IZ73Z0_152661 (SCOPES).

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  1. V. E. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine, Prospekt Nauky, 41, Kyiv, 03028, Ukraine

    O. V. Shynkarenko & S. A. Kravchenko

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  1. O. V. Shynkarenko
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Correspondence to O. V. Shynkarenko.

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Translated from Teoreticheskaya i Éksperimental’naya Khimiya, Vol. 51, No. 5, pp. 265–283, September-October, 2015.

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Shynkarenko, O.V., Kravchenko, S.A. Surface Plasmon Resonance Sensors: Methods of Surface Functionalization and Sensitivity Enhancement. Theor Exp Chem 51, 273–292 (2015). https://doi.org/10.1007/s11237-015-9427-5

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